Search Results - "Kasten, Georgia"

Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine by Kasten, Georgia, Nouri, Khatera, Grohganz, Holger, Rades, Thomas, Löbmann, Korbinian

“…[Display omitted] The introduction of a highly water soluble amino acid as co-amorphous co-former has previously been shown to significantly improve the…”
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In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine by Kasten, Georgia, Lobo, Lonita, Dengale, Swapnil, Grohganz, Holger, Rades, Thomas, Löbmann, Korbinian

“…[Display omitted] Liquid-assisted grinding (LAG) and dry ball milling (DBM) have recently been used to obtain different physical forms of drug-amino acid salts…”
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The use of molecular descriptors in the development of co-amorphous formulations by Meng-Lund, Helena, Kasten, Georgia, Jensen, Katrine Tarp, Poso, Antti, Pantsar, Tatu, Rades, Thomas, Rantanen, Jukka, Grohganz, Holger

“…Co-amorphous systems consisting of a drug and an amino acid have been investigated extensively for the enhancement of drug solubility and amorphous stability…”
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Co-former selection for co-amorphous drug-amino acid formulations by Kasten, Georgia, Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas

“…[Display omitted] We have previously developed a fast screening method on the ability of twenty amino acids (AA) to form co-amorphous formulations with six…”
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Development of a screening method for co-amorphous formulations of drugs and amino acids by Kasten, Georgia, Grohganz, Holger, Rades, Thomas, Löbmann, Korbinian

“…Using amino acids (AA) as low molecular weight excipients in the preparation of co-amorphous blends with the aim to stabilize the drug in the amorphous form…”
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The Role of Glass Transition Temperatures in Coamorphous Drug–Amino Acid Formulations by Kissi, Eric Ofosu, Kasten, Georgia, Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger

“…The improved physical stability associated with coamorphous drug–amino acid (AA) formulations may indicate a decrease in mobility of the amorphous drug…”
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Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations by Siqueira, Scheyla D.V.S., Müllertz, Anette, Gräeser, Kirsten, Kasten, Georgia, Mu, Huiling, Rades, Thomas

“…ABSTRACT The aim of this work was to evaluate the influence of drug load and physical form of cinnarizine (CIN) in self-nanoemulsifying drug delivery systems…”
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Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations by Kasten, Georgia, Duarte, Íris, Paisana, Maria, Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger

“…The feasibility of upscaling the formulation of co-amorphous indomethacin-lysine from lab-scale to pilot-scale spray drying was investigated. A 2² full…”
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Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery by Kasten, Georgia, Silva, Luis Felipe Costa, Lemos-Senna, Elenara

“…Context: The development of low-density polymeric microparticles may be a useful approach to deliver antibiotics such as azithromycin into the lung. Objective:…”
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Development of low density azithromycin-loaded polycaprolactone microparticles for pulmonary delivery by Kasten, Georgia, Silva, Luis Felipe Costa, Lemos-Senna, Elenara

“…The development of low-density polymeric microparticles may be a useful approach to deliver antibiotics such as azithromycin into the lung. The aim of this…”
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Preparation and characterization of quercetin-loaded solid lipid microparticles for pulmonary delivery by Silva, Luis Felipe Costa, Kasten, Georgia, de Campos, Carlos Eduardo Maduro, Chinelatto, Adilson Luiz, Lemos-Senna, Elenara

“…The aim of this study was to develop quercetin-loaded solid lipid microparticles intended to be inhaled. The microparticles were prepared from a mixture of…”
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