Search Results - "Kassmer, Susannah"
-
1
Cellular and molecular mechanisms of regeneration in colonial and solitary Ascidians
Published in Developmental biology (15-04-2019)“…Regenerative ability is highly variable among the metazoans. While many invertebrate organisms are capable of complete regeneration of entire bodies and…”
Get full text
Journal Article -
2
Evidence that ABC transporter-mediated autocrine export of an eicosanoid signaling molecule enhances germ cell chemotaxis in the colonial tunicate Botryllus schlosseri
Published in Development (Cambridge) (07-08-2020)“…The colonial ascidian regenerates the germline during repeated cycles of asexual reproduction. Germline stem cells (GSCs) circulate in the blood and migrate to…”
Get full text
Journal Article -
3
Integrin-alpha-6+ Candidate stem cells are responsible for whole body regeneration in the invertebrate chordate Botrylloides diegensis
Published in Nature communications (07-09-2020)“…Colonial ascidians are the only chordates able to undergo whole body regeneration (WBR), during which entire new bodies can be regenerated from small fragments…”
Get full text
Journal Article -
4
Colonial ascidians as model organisms for the study of germ cells, fertility, whole body regeneration, vascular biology and aging
Published in Current opinion in genetics & development (01-08-2016)“…Colonial ascidians are marine invertebrate chordates that are the closest invertebrate relative to the vertebrates. Colonies of Botryllus schlosseri undergo a…”
Get full text
Journal Article -
5
Very small embryonic-like cells: Biology and function of these potential endogenous pluripotent stem cells in adult tissues
Published in Molecular reproduction and development (01-08-2013)“…Very small embryonic‐like cells (VSELs), found in murine bone marrow and other adult tissues, are small, non‐hematopoietic cells expressing markers of…”
Get full text
Journal Article -
6
Gonad development and hermaphroditism in the ascidian Botryllus schlosseri
Published in Molecular reproduction and development (01-02-2017)“…SUMMARY The colonial ascidian Botryllus schlosseri is an ideal model organism for studying gonad development and hermaphroditism. B. schlosseri has been reared…”
Get full text
Journal Article -
7
Migration of germline progenitor cells is directed by sphingosine-1-phosphate signalling in a basal chordate
Published in Nature communications (12-10-2015)“…The colonial ascidian Botryllus schlosseri continuously regenerates entire bodies in an asexual budding process. The germ line of the newly developing bodies…”
Get full text
Journal Article -
8
Very Small Embryonic‐Like Stem Cells from the Murine Bone Marrow Differentiate into Epithelial Cells of the Lung
Published in Stem cells (Dayton, Ohio) (01-12-2013)“…The view that adult stem cells are lineage restricted has been challenged by numerous reports of bone marrow (BM)‐derived cells giving rise to epithelial…”
Get full text
Journal Article -
9
Whole body regeneration and developmental competition in two botryllid ascidians
Published in EvoDevo (15-12-2021)“…Botryllid ascidians are a group of marine invertebrate chordates that are colonial and grow by repeated rounds of asexual reproduction to form a colony of…”
Get full text
Journal Article -
10
Nonhematopoietic Cells are the Primary Source of Bone Marrow-Derived Lung Epithelial Cells
Published in Stem cells (Dayton, Ohio) (01-03-2012)“…Previous studies have demonstrated that bone marrow (BM)‐derived cells differentiate into nonhematopoietic cells of multiple tissues. To date, it remains…”
Get full text
Journal Article -
11
Detection of bone marrow–derived lung epithelial cells
Published in Experimental hematology (01-07-2010)“…Studies on the ability of bone marrow−derived cells to adopt the morphology and protein expression pattern of epithelial cells in vivo have expanded rapidly…”
Get full text
Journal Article -
12
Vascular regeneration in a basal chordate is due to the presence of immobile, bi-functional cells
Published in PloS one (01-04-2014)“…The source of tissue turnover during homeostasis or following injury is usually due to proliferation of a small number of resident, lineage-restricted stem…”
Get full text
Journal Article -
13
Vascular Aging in the Invertebrate Chordate, Botryllus schlosseri
Published in Frontiers in molecular biosciences (08-04-2021)“…Vascular diseases affect over 1 billion people worldwide and are highly prevalent among the elderly, due to a progressive deterioration of the structure of…”
Get full text
Journal Article -
14
A new antibody for the study of human CD157 expression and function
Published in The Journal of immunology (1950) (01-05-2023)“…CD157 is an ectoenzyme that has both cyclic ADP-ribose hydrolase and ADP-ribosyl cyclase activities. In the human hematopoietic system, CD157 is prevalently…”
Get full text
Journal Article -
15
Evidence that ABC-transporter-mediated autocrine export of an eicosanoid signaling molecule enhances germ cell chemotaxis in the colonial tunicate Botryllus schlosseri
Published in Development (Cambridge) (01-01-2020)“…The colonial ascidian Botryllus schlosseri regenerates the germline during repeated cycles of asexual reproduction. Germline stem cells (GSCs) circulate in the…”
Get full text
Journal Article -
16
Mechanisms of Vertebrate Germ Cell Determination
Published in Advances in experimental medicine and biology (01-01-2017)“…Two unique characteristics of the germ line are the ability to persist from generation to generation and to retain full developmental potential while…”
Get more information
Journal Article -
17
Aging in the colonial chordate, Botryllus schlosseri
Published in Invertebrate reproduction & development (30-01-2015)“…What mechanisms underlie aging? One theory, the wear-and-tear model, attributes aging to progressive deterioration in the molecular and cellular machinery…”
Get full text
Journal Article -
18
Bone Marrow Derived Lung Epithelial Cells Are Derived Predominantly From Nonhematopoietic Cells
Published in Blood (19-11-2010)“…Abstract 2615 Since 1998, there have been many discoveries that bone marrow derived cells (BMDC) possess the ability to cross lineage barriers and…”
Get full text
Journal Article -
19
The stromal cell‐derived factor‐1α dependent migration of human cord blood CD34+ haematopoietic stem and progenitor cells switches from protein kinase C (PKC)‐α dependence to PKC‐α independence upon prolonged culture in the presence of Flt3‐ligand and interleukin‐6
Published in British journal of haematology (01-09-2008)“…Summary Addition of the inflammatory cytokine interleukin (IL)‐6 to the culture medium of human cord blood haematopoietic stem and progenitor cells (HSPCs) has…”
Get full text
Journal Article -
20
The stromal cell-derived factor-1 alpha dependent migration of human cord blood CD34 super(+) haematopoietic stem and progenitor cells switches from protein kinase C (PKC)- alpha dependence to PKC- alpha independence upon prolonged culture in the presence of Flt3-ligand and interleukin-6
Published in British journal of haematology (01-09-2008)“…Addition of the inflammatory cytokine interleukin (IL)-6 to the culture medium of human cord blood haematopoietic stem and progenitor cells (HSPCs) has been…”
Get full text
Journal Article