Search Results - "Kassis, Haifa"
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Medical Writing for Continuing Education in the Health Professions: A Competency Model
Published in Journal of CME (31-12-2024)“…Medical writers assist continuing medical education (CME)/continuing professional development (CPD) providers in planning and delivering educational…”
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MicroRNA-146a Promotes Oligodendrogenesis in Stroke
Published in Molecular neurobiology (01-01-2017)“…Stroke induces new myelinating oligodendrocytes that are involved in ischemic brain repair. Molecular mechanisms that regulate oligodendrogenesis have not been…”
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MicroRNA profiling in subventricular zone after stroke: MiR-124a regulates proliferation of neural progenitor cells through Notch signaling pathway
Published in PloS one (26-08-2011)“…The Notch signaling pathway regulates adult neurogenesis under physiological and pathophysiological conditions. MicroRNAs are small non-coding RNA molecules…”
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MicroRNA-17-92 Cluster Mediates the Proliferation and Survival of Neural Progenitor Cells after Stroke
Published in The Journal of biological chemistry (03-05-2013)“…The role of microRNAs (miRNAs) in mediating adult neurogenesis after stroke has not been extensively studied. The present study investigated the function of…”
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Epigenetics in Stroke Recovery
Published in Genes (27-02-2017)“…While the death rate from stroke has continually decreased due to interventions in the hyperacute stage of the disease, long-term disability and…”
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Targeting histone deacetylation for recovery of maternal deprivation-induced changes in BDNF and AKAP150 expression in the VTA
Published in Experimental neurology (01-11-2018)“…Severe early life stressors increase the probability of developing psychiatric disorders later in life through modifications in neuronal circuits controlling…”
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Stroke Induces Nuclear Shuttling of Histone Deacetylase 4
Published in Stroke (1970) (01-07-2015)“…BACKGROUND AND PURPOSE—Histone deacetylases (HDACs) 4 and 5 are abundantly expressed in the brain and have been implicated in the regulation of…”
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Histone deacetylase expression in white matter oligodendrocytes after stroke
Published in Neurochemistry international (01-11-2014)“…•Stroke-induced oligodendrogenesis is associated with distinct profiles of HDACs.•Stroke increases HDAC1, HDAC2 and HDAC4 positive OPCs.•A decrease in HDAC1…”
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Combination Therapy With VELCADE and Tissue Plasminogen Activator Is Neuroprotective in Aged Rats After Stroke and Targets MicroRNA-146a and the Toll-Like Receptor Signaling Pathway
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2012)“…OBJECTIVE—Activation of the toll-like receptor (TLR) signaling pathway exacerbates ischemic brain damage. The present study tested the hypothesis that…”
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MicroRNAs in the axon locally mediate the effects of chondroitin sulfate proteoglycans and cGMP on axonal growth
Published in Developmental neurobiology (Hoboken, N.J.) (01-12-2015)“…ABSTRACT Axonal miRNAs locally regulate axonal growth by modulating local protein composition. Whether localized miRNAs in the axon mediate the inhibitory…”
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Morphine-induced synaptic plasticity in the VTA is reversed by HDAC inhibition
Published in Journal of neurophysiology (01-09-2016)“…Dopamine (DA) dysfunction originating from the ventral tegmental area (VTA) occurs as a result of synaptic abnormalities following consumption of drugs of…”
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Valproic acid increases white matter repair and neurogenesis after stroke
Published in Neuroscience (18-09-2012)“…Highlights ► We assessed the effect of HDAC inhibitor–VPA on post-stroke recovery. ► The administration of VPA starting 24 h after stroke improved neurological…”
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Class IIa histone deacetylases affect neuronal remodeling and functional outcome after stroke
Published in Neurochemistry international (01-06-2016)“…We have previously demonstrated that stroke induces nuclear shuttling of class IIa histone deacetylase 4 (HDAC4). Stroke-induced nuclear shuttling of HDAC4 is…”
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HDAC4 Shuttling Promotes Neuronal Remodeling After Stroke (S5.007)
Published in Neurology (06-04-2015)“…Abstract only…”
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HDAC4 Shuttling Promotes Neuronal Remodeling After Stroke (I10-1C)
Published in Neurology (06-04-2015)“…Abstract only…”
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Abstract W P107: HDAC4 Shuttling in Interneurons and Pyramidal Neurons is Associated with Improved Axonal Density and Myelination after Stroke
Published in Stroke (1970) (01-02-2015)“…Abstract only Background: We have previously demonstrated that stroke induces nuclear shuttling of histone deacetylase 4 (HDAC4) in neurons during stroke…”
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Abstract T P69: Stroke Induces HDAC4 Nuclear Shuttling in Neurons
Published in Stroke (1970) (01-02-2014)“…Abstract only Background: Nuclear shuttling of class II histone deacetylases (HDACs) in neurons regulates apoptosis and facilitates neuronal recovery in…”
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Abstract 127: Class IIa Histone Deacetylases Are Essential for Neuronal Remodeling and Functional Recovery After Stroke
Published in Stroke (1970) (01-02-2016)“…Abstract only Background: Histone deacetylases (HDACs) have recently emerged as a potential therapeutic target for stroke. We have previously demonstrated that…”
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Abstract TMP71: Role Of Histone Deacetylases in Stroke-induced Oligodendrogenesis
Published in Stroke (1970) (01-02-2013)“…Abstract only Background: Histone deacetylases (HDACs) are a superfamily of isoforms that deacetylate lysine residues in histones. HDAC activity is essential…”
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Abstract 134: Agonaute 2 Regulates Neurogenesis In Ischemic Neural Progenitor Cells
Published in Stroke (1970) (01-02-2013)“…Abstract only Background: Molecular mechanisms underlying stroke-induced neurogenesis have not been fully investigated. Argonaute 2 (Ago2) is the central…”
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