Search Results - "Kassem, Ahmed Alaa"
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Niosomes as a potential drug delivery system for increasing the efficacy and safety of nystatin
Published in Drug development and industrial pharmacy (01-12-2011)“…Nonionic surfactant (NIS) vesicles (niosomes) formed from self-assembly of hydrated synthetic NIS monomers are capable of entrapping a variety of drugs and…”
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Benzocaine loaded solid lipid nanoparticles: Formulation design, in vitro and in vivo evaluation of local anesthetic effect
Published in Current drug delivery (01-12-2015)“…The aim of the present work is the development and evaluation of solid lipid nanoparticles (SLNs) as carrier system for topical delivery of benzocaine (BZC)…”
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3
Boswellia carterii liquisolid systems with promoted anti-inflammatory activity
Published in Current drug delivery (01-01-2015)“…(BC) Birdwood oleogum resin is an ancient remedy of inflammation processes known since Ancient Egyptian time. Of boswellic acids, 3-acetyl-11-keto-β-boswellic…”
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4
Comparative study of liposomes, ethosomes and transfersomes as carriers for enhancing the transdermal delivery of diflunisal: In vitro and in vivo evaluation
Published in International journal of pharmaceutics (30-05-2019)“…[Display omitted] The current study aimed to develop an effective transdermal nanovesicular carrier of diflunisal that provides enhanced delivery through the…”
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5
Development of acetazolamide loaded bilosomes for improved ocular delivery: Preparation, characterization and in vivo evaluation
Published in Journal of drug delivery science and technology (01-10-2020)“…Acetazolamide (ACZ), a carbonic anhydrase inhibitor, is employed to decrease the intraocular pressure (IOP) in glaucoma patients. ACZ is characterized by low…”
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Enhancement of 8-methoxypsoralen topical delivery via nanosized niosomal vesicles: Formulation development, in vitro and in vivo evaluation of skin deposition
Published in International journal of pharmaceutics (30-01-2017)“…[Display omitted] The aim of the present study is to enhance the skin penetration and deposition of 8-methoxypsoraln (8-MOP) via niosomal vesicles to increase…”
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7
Topical nanostructured lipid carriers/inorganic sunscreen combination for alleviation of all-trans retinoic acid-induced photosensitivity: Box-Behnken design optimization, in vitro and in vivo evaluation
Published in European journal of pharmaceutical sciences (15-06-2019)“…All-trans retinoic acid is a natural retinoid and the physiologically active metabolite of vitamin A. The aim of the present study is to develop and optimize a…”
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8
Self-nanoemulsifying drug delivery system (SNEDDS) with enhanced solubilization of nystatin for treatment of oral candidiasis: Design, optimization, in vitro and in vivo evaluation
Published in Journal of molecular liquids (01-06-2016)“…The aim of the present study is to develop and optimize self-nanoemulsifying drug delivery systems (SNEDDSs) to improve the per-oral bioavailability of poorly…”
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9
Chitosan/β-glycerophosphate in situ forming thermo-sensitive hydrogel for improved ocular delivery of moxifloxacin hydrochloride
Published in European journal of pharmaceutical sciences (01-12-2021)“…The aim of the current work is to develop a thermo-sensitive hydrogel system of moxifloxacin hydrochloride (MOX) for improved ocular delivery. Fifteen…”
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Formulation and optimization of cationic nanoemulsions for enhanced ocular delivery of dorzolamide hydrochloride using Box-Behnken design: In vitro and in vivo assessments
Published in Journal of drug delivery science and technology (01-02-2022)“…The present study was designed to develop dorzolamide HCl (DRZ) loaded cationic nanoemulsions (CNEs) for enhanced ocular delivery. CNEs were prepared employing…”
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Topical caffeine-loaded nanostructured lipid carriers for enhanced treatment of cellulite: A 32 full factorial design optimization and in vivo evaluation in rats
Published in International journal of pharmaceutics (25-08-2023)“…[Display omitted] The goal of this study was the development and evaluation of semisolid caffeine (CAF) loaded nanostructured lipid carriers (NLCs) for topical…”
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12
Hydrophobic ion pair loaded self-emulsifying drug delivery system (SEDDS): A novel oral drug delivery approach of cromolyn sodium for management of bronchial asthma
Published in International journal of pharmaceutics (30-07-2020)“…[Display omitted] The aim of the present study is to develop a self-emulsifying drug delivery system (SEDDS) for the hydrophobic ion pair (HIP) complex of…”
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13
Chrysin-phospholipid complex-based solid dispersion for improved anti-aging and neuroprotective effects in mice
Published in Pharmaceutical development and technology (02-01-2023)“…The present study aimed to improve the neuroprotective effect of chrysin (CHR) by combining two formulation techniques, phospholipid (PL) complexation and…”
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14
Phospholipid complex enriched micelles: A novel drug delivery approach for promoting the antidiabetic effect of repaglinide
Published in European journal of pharmaceutical sciences (01-03-2017)“…To enhance the oral antidiabetic effect of repaglinide (RG), a newly emerging approach, based on the combination of phospholipid complexation and micelle…”
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Vitamin D3-Loaded Nanoemulsions as a Potential Drug Delivery System for Autistic Children: Formulation Development, Safety, and Pharmacokinetic Studies
Published in AAPS PharmSciTech (09-02-2023)“…The aim of the current study is the development of a vitamin D 3 (VD3)-loaded nanoemulsion (NE) formulation to improve VD3 oral bioavailability for management…”
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Improved hepatoprotective activity of Beta vulgaris L. leaf extract loaded self-nanoemulsifying drug delivery system (SNEDDS): in vitro and in vivo evaluation
Published in Drug development and industrial pharmacy (02-10-2020)“…Beta vulgaris L. (beetroot) is a vegetable plant rich in phytochemical compounds such as phenolic acids, carotenoids and flavonoids. The objective of the…”
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Design and evaluation of bioenhanced oral tablets of Dunaliella salina microalgae for treatment of liver fibrosis
Published in Journal of drug delivery science and technology (01-10-2020)“…The application of Dunaliella salina (D. salina) microalgae in nutraceutical products is limited due to poor aqueous solubility and consequently low…”
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Development of folic acid-loaded nanostructured lipid carriers for topical delivery: preparation, characterisation and ex vivo investigation
Published in Journal of microencapsulation (03-07-2020)“…The present work is designed to achieve efficient localised skin delivery of folic acid (FA)-loaded nanostructured lipid carriers (NLCs) to infer efficient…”
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Topical caffeine-loaded nanostructured lipid carriers for enhanced treatment of cellulite: A 3 2 full factorial design optimization and in vivo evaluation in rats
Published in International journal of pharmaceutics (25-07-2023)“…The goal of this study was the development and evaluation of semisolid caffeine (CAF) loaded nanostructured lipid carriers (NLCs) for topical treatment of…”
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20
Transdermal cumin essential oil nanoemulsions with potent antioxidant and hepatoprotective activities: In-vitro and in-vivo evaluation
Published in Journal of molecular liquids (01-12-2015)“…Cumin is an annual herb from Apiaceae family. Cumin seeds possess good content of phenolic compounds which show considerable free radical scavenging activity…”
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