Search Results - "Kasprowicz, Deborah J"

IL-2Rβ links IL-2R signaling with Foxp3 expression by Soper, David M, Kasprowicz, Deborah J, Ziegler, Steven F

“…Immunological tolerance to self antigens is a tightly regulated process. Recent work has demonstrated that the forkhead family member Foxp3 is a critical…”
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The Generation of Mature, Single-Positive Thymocytes In Vivo Is Dysregulated by CD69 Blockade or Overexpression by Nakayama, Toshinori, Kasprowicz, Deborah J, Yamashita, Masakatsu, Schubert, Lisa A, Gillard, Geoffery, Kimura, Motoko, Didierlaurent, Arnaud, Koseki, Haruhiko, Ziegler, Steven F

“…During development in the thymus, mature CD4+ or CD8+ cells are derived from immature CD4+CD8+ cells through a series of selection events. One of the hallmarks…”
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Cutting Edge: Anti-CD25 Monoclonal Antibody Injection Results in the Functional Inactivation, Not Depletion, of CD4+CD25+ T Regulatory Cells by Kohm, Adam P, McMahon, Jeffrey S, Podojil, Joseph R, Begolka, Wendy Smith, DeGutes, Mathew, Kasprowicz, Deborah J, Ziegler, Steven F, Miller, Stephen D

“…CD4+CD25+ T regulatory (T(R)) cells are an important regulatory component of the adaptive immune system that limit autoreactive T cell responses in various…”
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Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance by Dillon, Stephanie, Agrawal, Sudhanshu, Banerjee, Kaustuv, Letterio, John, Denning, Timothy L, Oswald-Richter, Kyra, Kasprowicz, Deborah J, Kellar, Kathryn, Pare, Jeff, van Dyke, Thomas, Ziegler, Steven, Unutmaz, Derya, Pulendran, Bali

“…Emerging evidence suggests critical roles for APCs in suppressing immune responses. Here, we show that zymosan, a stimulus for TLR2 and dectin-1, regulates…”
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Scurfin (FoxP3) Controls T-Dependent Immune Responses In Vivo Through Regulation of CD4+ T Cell Effector Function by Kasprowicz, Deborah J, Smallwood, P. Scott, Tyznik, Aaron J, Ziegler, Steven F

“…Scurfin, the protein product of the FoxP3 gene, is a forkhead-family transcription factor that negatively regulates T cell function. Mice carrying a…”
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Stimulation of the B Cell Receptor, CD86 (B7-2), and the β2-Adrenergic Receptor Intrinsically Modulates the Level of IgG1 and IgE Produced per B Cell by Kasprowicz, Deborah J., Kohm, Adam P., Berton, Michael T., Chruscinski, Andrezj J., Sharpe, Arlene, Sanders, Virginia M.

“…Abstract Our findings using B cells from either wild-type, CD86-deficient, or β2-adrenergic receptor (β2AR)-deficient mice suggest three mechanisms by which…”
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Dynamic regulation of FoxP3 expression controls the balance between CD4+ T cell activation and cell death by Kasprowicz, Deborah J., Droin, Nathalie, Soper, David M., Ramsdell, Fred, Green, Douglas R., Ziegler, Steven F.

“…The forkhead‐family transcription factor FoxP3 is important for the development and function of CD4+CD25+ regulatory T cells. While the overall phenotypic…”
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Adaptive immunity in mice lacking the β2-adrenergic receptor by Sanders, Virginia M, Kasprowicz, Deborah J, Swanson-Mungerson, Michelle A, Podojil, Joseph R, Kohm, Adam P

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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells by Walker, Mindi R, Kasprowicz, Deborah J, Gersuk, Vivian H, Benard, Angele, Van Landeghen, Megan, Buckner, Jane H, Ziegler, Steven F

“…CD4+CD25+ regulatory T (TR) cells have been described in both humans and mice. In mice, TR are thymically derived, and lack of TR leads to organ-specific…”
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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells by R.Walker, Mindi, Kasprowicz, Deborah J., Gersuk, Vivian H., Bènard, Angéle, Van Landeghen, Megan, Buckner, Jane H., Ziegler, Steven F.

“…CD4 + CD25 + regulatory T (T R ) cells have been described in both humans and mice. In mice, T R are thymically derived, and lack of T R leads to…”
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IL-2Rbeta links IL-2R signaling with Foxp3 expression by Soper, David M, Kasprowicz, Deborah J, Ziegler, Steven F

“…Immunological tolerance to self antigens is a tightly regulated process. Recent work has demonstrated that the forkhead family member Foxp3 is a critical…”
Get full text

IL-2R square links IL-2R signaling with Foxp3 expression by Soper, David M, Kasprowicz, Deborah J, Ziegler, Steven F

“…Immunological tolerance to self antigens is a tightly regulated process. Recent work has demonstrated that the forkhead family member Foxp3 is a critical…”
Get full text

Dynamic regulation of FoxP3 expression controls the balance between CD4 super(+) T cell activation and cell death by Kasprowicz, Deborah J, Droin, Nathalie, Soper, David M, Ramsdell, Fred, Green, Douglas R, Ziegler, Steven F

“…The forkhead-family transcription factor FoxP3 is important for the development and function of CD4 super(+)CD25 super(+) regulatory T cells. While the overall…”
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Adaptive immunity in mice lacking the beta(2)-adrenergic receptor by Sanders, Virginia M, Kasprowicz, Deborah J, Swanson-Mungerson, Michelle A, Podojil, Joseph R, Kohm, Adam P

“…The beta-2-adrenergic receptor (beta(2)AR) is expressed by most lymphocyte populations and binds the sympathetic neurotransmitter norepinephrine (NE)…”
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Anti-CD25 Monoclonal Antibody Injection Results in the Functional Inactivation, Not Depletion, of CD4 super(+)CD25 super(+) T Regulatory Cells by Kohm, Adam P, McMahon, Jeffrey S, Podojil, Joseph R, Begolka, Wendy Smith, DeGutes, Mathew, Kasprowicz, Deborah J, Ziegler, Steven F, Miller, Stephen D

“…CD4 super(+)CD25 super(+) T regulatory (T sub(R)) cells are an important regulatory component of the adaptive immune system that limit autoreactive T cell…”
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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4^sup +^CD25^sup -^ T cells by Walker, Mindi R, Kasprowicz, Deborah J, Gersuk, Vivian H, Benard, Angele

“…CD4+CD25+ regulatory T (TR) cells have been described in both humans and mice. In mice, TR are thymically derived, and lack of TR leads to organ-specific…”
Get full text

Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigenpresenting cells and immunological tolerance by Dillon, Stephanie, Agrawal, Sudhanshu, Banerjee, Kaustuv, Letterio, John, Denning, Timothy L, Oswald-Richter, Kyra, Kasprowicz, Deborah J, Kellar, Kathryn, Pare, Jeff, Dyke, Thomas van, Ziegler, Steven, Unutmaz, Derya, Pulendran, Bali

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Adaptive immunity in mice lacking the β 2-adrenergic receptor by Sanders, Virginia M, Kasprowicz, Deborah J, Swanson-Mungerson, Michelle A, Podojil, Joseph R, Kohm, Adam P

“…The beta-2-adrenergic receptor (β 2AR) is expressed by most lymphocyte populations and binds the sympathetic neurotransmitter norepinephrine (NE). Stimulation…”
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Stimulation of the B Cell Receptor, CD86 (B7-2), and the {beta}2-Adrenergic Receptor Intrinsically Modulates the Level of IgG1 and IgE Produced per B Cell by Kasprowicz, Deborah J, Kohm, Adam P, Berton, Michael T, Chruscinski, Andrezj J, Sharpe, Arlene, Sanders, Virginia M

Get full text