Search Results - "Kasper, Piotr T"
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Mass Spectrometric Analysis of Intact Human Monoclonal Antibody Aggregates Fractionated by Size-Exclusion Chromatography
Published in Pharmaceutical research (01-10-2010)“…Purpose The aim of this study was to develop a method to characterize intact soluble monoclonal IgG1 antibody (IgG) oligomers by mass spectrometry. Methods IgG…”
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Metabolite Identification Using Automated Comparison of High-Resolution Multistage Mass Spectral Trees
Published in Analytical chemistry (Washington) (03-07-2012)“…Multistage mass spectrometry (MS n ) generating so-called spectral trees is a powerful tool in the annotation and structural elucidation of metabolites and is…”
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Elemental composition determination based on MSn
Published in Bioinformatics (Oxford, England) (01-09-2011)Get full text
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Computer‐assisted mass spectrometric analysis of naturally occurring and artificially introduced cross‐links in proteins and protein complexes
Published in The FEBS journal (01-01-2006)“…A versatile software tool, virtualmslab, is presented that can perform advanced complex virtual proteomic experiments with mass spectrometric analyses to…”
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Mild and Chemoselective Peptide-Bond Cleavage of Peptides and Proteins at Azido Homoalanine
Published in Angewandte Chemie International Edition (09-12-2005)“…A gentle break: Cleavage of peptides containing the non‐natural but proteogenic amino acid azido homoalanine can be accomplished by phosphine‐ or…”
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Elemental composition determination based on MS(n)
Published in Bioinformatics (Oxford, England) (01-09-2011)“…Identification of metabolites is essential for its use as biomarkers, for research in systems biology and for drug discovery. The first step before a structure…”
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Fragmentation trees for the structural characterisation of metabolites
Published in Rapid communications in mass spectrometry (15-10-2012)“…Metabolite identification plays a crucial role in the interpretation of metabolomics research results. Due to its sensitivity and widespread implementation, a…”
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An Aptly Positioned Azido Group in the Spacer of a Protein Cross-Linker for Facile Mapping of Lysines in Close Proximity
Published in Chembiochem : a European journal of chemical biology (23-07-2007)“…Cross‐links between amino acid residues in close proximity can provide distance constraints for the validation of models of the 3D structure proteins. The…”
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Quantitation of newly synthesized proteins by pulse labeling with azidohomoalanine
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2011)“…Measuring protein synthesis and degradation rates on a proteomic scale is an important step toward modeling the kinetics in complicated cellular response…”
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Elemental composition determination based on MS n
Published in Bioinformatics (Oxford, England) (01-09-2011)“…Abstract Motivation: Identification of metabolites is essential for its use as biomarkers, for research in systems biology and for drug discovery. The first…”
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Mild and Chemoselective Peptide-Bond Cleavage of Peptides and Proteins at Azido Homoalanine
Published in Angewandte Chemie (09-12-2005)“…Ein sanfter Bruch: Peptide, die die nichtnatürliche, aber proteogene Aminosäure Azidohomoalanin enthalten, lassen sich durch Phosphan‐ oder Dithiol‐vermittelte…”
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Mild and Chemoselective Peptide‐Bond Cleavage of Peptides and Proteins at Azido Homoalanine
Published in Angewandte Chemie (09-12-2005)Get full text
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