Search Results - "Kasper, M"
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LC3/GABARAP family proteins: autophagy‐(un)related functions
Published in The FASEB journal (01-12-2016)“…ABSTRACT From yeast to mammals, autophagy is an important mechanism for sustaining cellular homeostasis through facilitating the degradation and recycling of…”
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2
Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells
Published in BMC cancer (02-04-2018)“…Mounting evidence suggests that one of the ways that cells adapt to hypoxia is through alternative splicing. The aim of this study was firstly to examine the…”
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3
Double-Headed 2′-Deoxynucleotides That Hybridize to DNA and RNA Targets via Normal and Reverse Watson–Crick Base Pairs
Published in Journal of organic chemistry (15-04-2022)“…Through the use of modified nucleotides, synthetic nucleic acids have found several fields of application within biotechnology and in the pharmaceutical…”
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4
Elevated remnant cholesterol, plasma triglycerides, and cardiovascular and non-cardiovascular mortality
Published in European heart journal (21-04-2023)“…Cholesterol carried in triglyceride-rich lipoproteins, also called remnant cholesterol, is being increasingly acknowledged as an important causal risk factor…”
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5
Estimating disability prevalence and disability-related inequalities: Does the choice of measure matter?
Published in Social science & medicine (1982) (01-03-2021)“…Different measures for quantifying the percentage of people with a disability in surveys result in diverging estimates of prevalence and disability-related…”
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6
EGFR signaling and autophagy dependence for growth, survival, and therapy resistance
Published in Cell cycle (Georgetown, Tex.) (01-01-2014)“…The epidermal growth factor receptor (EGFR) is amplified or mutated in various human epithelial tumors. Its expression and activation leads to cell…”
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7
BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage
Published in Nature communications (14-08-2020)“…Proper chromatin function and maintenance of genomic stability depends on spatiotemporal coordination between the transcription and replication machinery. Loss…”
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8
FUNDAMENTAL LIMITATIONS OF HIGH CONTRAST IMAGING SET BY SMALL SAMPLE STATISTICS
Published in The Astrophysical journal (10-09-2014)“…In this paper, we review the impact of small sample statistics on detection thresholds and corresponding confidence levels (CLs) in high-contrast imaging at…”
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High-accuracy short-term precipitable water-vapour operational forecast at the Very Large Telescope and perspectives for sky background forecast
Published in Monthly notices of the Royal Astronomical Society (01-10-2020)“…ABSTRACT In this article, we present the first results ever obtained by applying the autoregressive (AR) technique to precipitable water vapour (PWV). The…”
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10
Elevated remnant cholesterol and atherosclerotic cardiovascular disease in diabetes: a population-based prospective cohort study
Published in Diabetologia (01-12-2023)“…Aims/hypothesis Elevated remnant cholesterol is observationally and causally associated with increased risk of atherosclerotic cardiovascular disease (ASCVD)…”
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11
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
Published in Proceedings of the National Academy of Sciences - PNAS (19-03-2013)“…Hypoxia is a common feature of tumors and an important contributor to malignancy and treatment resistance. The ability of tumor cells to survive hypoxic stress…”
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12
Lower levels of small HDL particles associated with increased infectious disease morbidity and mortality: a population-based cohort study of 30 195 individuals
Published in Cardiovascular research (02-05-2023)“…Abstract Aims Low levels of HDL cholesterol have been associated with increased risk of infectious disease morbidity and mortality. Nuclear magnetic resonance…”
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13
Voter turnout and municipal amalgamations-evidence from Denmark
Published in Local government studies (03-09-2019)“…The study utilizes evidence from the Danish 2007 municipal reform to inquire into the relationship between municipal amalgamations and voter turnout, that is,…”
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14
Cellular heterogeneity and microenvironmental control of skin cancer
Published in Journal of internal medicine (01-05-2021)“…Healthy tissues harbour a surprisingly high number of cells that carry well‐known cancer‐causing mutations without impacting their physiological function. In…”
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15
HILIC–MRM–MS for Linkage-Specific Separation of Sialylated Glycopeptides to Quantify Prostate-Specific Antigen Proteoforms
Published in Journal of proteome research (02-07-2020)“…Elevated serum prostate-specific antigen (PSA) levels in body fluids may indicate prostate cancer (PCa), but it is noted that the clinical performance is…”
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16
Campaigns Matter: How Voters Become Knowledgeable and Efficacious During Election Campaigns
Published in Political communication (03-04-2014)“…Election campaigns are more than simple competitions for votes; they also represent an opportunity for voters to become politically knowledgeable and engaged…”
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Hypoxic Activation of the PERK/eIF2α Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3
Published in Clinical cancer research (15-11-2013)“…Conditions of poor oxygenation (hypoxia) are present in many human tumors, including cervix cancer, and are associated with increased risk of metastasis and…”
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18
How learning spaces matter in entrepreneurship education: introducing the concept of topopraxis
Published in Entrepreneurship and regional development (15-03-2023)“…Research into entrepreneurship education has explored content, audience and pedagogy but much is still to be studied when it comes to the spatial dimensions of…”
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19
Giant Planet Imaged in the Disk of the Young Star β Pictoris
Published in Science (American Association for the Advancement of Science) (02-07-2010)“…Here, we show that the approximately 10-million-year-old β Pictoris system hosts a massive giant planet, β Pictoris b, located 8 to 15 astronomical units from…”
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Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles
Published in The FASEB journal (01-05-2020)“…Iron homeostasis is essential for mitochondrial function, and iron deficiency has been associated with skeletal muscle weakness and decreased exercise capacity…”
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