Search Results - "Kaslow, D.C."

Meeting Report: WHO consultation on considerations for regulatory expectations of Zika virus vaccines for use during an emergency by Vannice, K.S, Giersing, B.K, Kaslow, D.C, Griffiths, E, Meyer, H, Barrett, A, Durbin, A.P, Wood, D, Hombach, J

“…Abstract On 1 February 2016, in the context of the ongoing Zika virus epidemic, the WHO declared that the recently reported clusters of microcephaly and other…”
Get full text

Stage-specific processing of Pfs230, a Plasmodium falciparum transmission-blocking vaccine candidate by Williamson, K.C., Fujioka, H., Aikawa, M., Kaslow, D.C.

“…During Plasmodium falciparum gametocytogenesis, Pfs230, a malaria transmission-blocking vaccine candidate, is expressed as a 360 kDa protein localized to the…”
Get full text

Plasmodium: parasite chitinase and its role in malaria transmission by Shahabuddin, M, Kaslow, D C

Get more information

Unique Specificity of in Vitro Inhibition of Mosquito Midgut Trypsin-like Activity Correlates with in Vivo Inhibition of Malaria Parasite Infectivity by Shahabuddin, M., Criscio, M., Kaslow, D.C.

“…Synchrony in the egress of Plasmodium ookinetes from the food bolus and enzymatic digestion of the blood meal in the mosquito midgut suggests that digestive…”
Get full text

Identification of two cysteine-rich, lipophilic proteins on the surface of Plasmodium knowlesi ookinetes: Pks20 and Pks24 by Fried, M, Gwadz, R W, Kaslow, D C

Get more information

Cryopreservation of Plasmodium falciparum gametocytes by Keister, D B, Kaslow, D C

Get more information

Developmental arrest of the human malaria parasite Plasmodium falciparum within the mosquito midgut via CTRP gene disruption by Templeton, T.J, Kaslow, D.C, Fidock, D.A

“…Apicomplexan protozoa possess a family of micronemal and cell surface‐associated proteins, each comprised a combination of cell‐adhesive vertebrate von…”
Get full text

Chitinases of the Avian Malaria Parasite Plasmodium gallinaceum, a Class of Enzymes Necessary for Parasite Invasion of the Mosquito Midgut by Vinetz, Joseph M., Valenzuela, Jesus G., Specht, Charles A., Aravind, L., Langer, Rebecca C., Ribeiro, Jose M.C., Kaslow, David C.

“…The Plasmodium ookinete produces chitinolytic activity that allows the parasite to penetrate the chitin-containing peritrophic matrix surrounding the blood…”
Get full text

Cloning and cross-species comparison of the thrombospondin-related anonymous protein (TRAP) gene from Plasmodium knowlesi, Plasmodium vivax and Plasmodium gallinaceum by Templeton, T.J, Kaslow, D.C

“…To examine the structure of the Plasmodium sporozoite micronemal protein, thrombospondin-related anonymous protein (TRAP) we have isolated TRAP genes from…”
Get full text

Antibody-mediated inhibition of Aedes aegypti midgut trypsins blocks sporogonic development of Plasmodium gallinaceum by Shahabuddin, M. (NIH, Bethesda, MD.), Lemos, F.J.A, Kaslow, D.C, Jacobs-Lorena, M

“…The peritrophic matrix (PM) that forms around a blood meal is a potential barrier for Plasmodium development in mosquitoes. Previously, we have shown that to…”
Get full text

A novel 40-kDa membrane-associated EF-hand calcium-binding protein in Plasmodium falciparum by RAWLING, D. J, KASLOW, D. C

“…A 40-kDa sexual stage radiolabeled surface protein of Plasmodium falciparum, Pfs40, was previously identified as a potential target antigen of transmission…”
Get full text

Transition phase in the production of recombinant proteins in yeast under the ADH2 promoter : An important step for reproducible manufacturing of a malaria transmission blocking vaccine candidate by NORONHA, S. B, KASLOW, D. C, SHILOACH, J

“…TBV25H, a malaria transmission blocking vaccine candidate, has been cloned in Saccharomyces cerevisiae under the control of the glucose repressed ADH2…”
Get full text

Transmission-blocking vaccines by Kaslow, David C

Get more information

Comparison of the primary structure of the 25 kDa ookinete surface antigens of Plasmodium falciparum and Plasmodium gallinaceum reveal six conserved regions by Kaslow, D C, Syin, C, McCutchan, T F, Miller, L H

“…The gene encoding the 25 kDa ookinete surface antigen (Pgs25) of Plasmodium gallinaceum has been cloned using an oligonucleotide probe directed against one of…”
Get more information

Plasmodium gallinaceum: Mosquito Peritrophic Matrix and the Parasite-Vector Compatibility by Shahabuddin, M., Kaidoh, T., Aikawa, M., Kaslow, D.C.

“…Transmission of malaria parasites occurs by relatively few species of mosquitoes. One proposed mechanism of refractoriness is an inability of certain…”
Get full text

A novel glucose-6-phosphate dehydrogenase in Plasmodium falciparum: cDNA and primary protein structure by Shahabuddin, M, Rawlings, D J, Kaslow, D C

“…The structure of the parasite-encoded G6PD (PfG6PD) may provide clues about the relative protection against malaria in humans with glucose-6-phosphate…”
Get more information

Comparison of factor IX methylation on human active and inactive X chromosomes: implications for X inactivation and transcription of tissue‐specific genes by Cullen, C.R., Hubberman, P., Kaslow, D.C., Migeon, B.R.

“…Maintenance of dosage compensation for housekeeping genes on the human X chromosome is mediated through differential methylation of clustered CpG nucleotides…”
Get full text

Production, Purification and Immunogenicity of a Malaria Transmission-Blocking Vaccine Candidate: TBV25H Expressed in Yeast and Purified Using Nickel-NTA Agarose by Kaslow, David C, Shiloach, Joseph

“…We have constructed a second generation malaria transmission-blocking vaccine candidate based on Pfs25, the predominate surface protein of Plasmodium…”
Get full text

The need for assays predictive of protection in development of malaria bloodstage vaccines by Miller, L.H., Good, M.F., Kaslow, D.C.

Get full text

The developmental effects of prostaglandin D2 on the pulmonary and systemic circulations in the newborn lamb by Soifer, S J, Morin, 3rd, F C, Kaslow, D C, Heymann, M A

“…Prostaglandin D2 (PGD2) lowers pulmonary arterial blood pressure without changing systemic arterial blood pressure in fetal and newborn lambs but increases…”
Get more information