Search Results - "Kask, Ants"

The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y by Kask, Ants, Harro, Jaanus, von Hörsten, Stephan, Redrobe, John P., Dumont, Yvan, Quirion, Rémi

“…This review aims to give a brief overview of NPY receptor distribution and physiology in the brain and summarizes series of studies, test by test and region by…”
Get full text

Novel and sensitive high-performance liquid chromatographic method based on electrochemical coulometric array detection for simultaneous determination of catecholamines, kynurenine and indole derivatives of tryptophan by Vaarmann, Annika, Kask, Ants, Mäeorg, Uno

“…A novel and simple method has been developed for the simultaneous quantification of tryptophan, kynurenine and indole derivatives as well as four…”
Get full text

Chronic variable stress and partial 5-HT denervation by parachloroamphetamine treatment in the rat: effects on behavior and monoamine neurochemistry by Harro, Jaanus, Tõnissaar, Margus, Eller, Marika, Kask, Ants, Oreland, Lars

“…Chronic variable stress (CVS) and manipulations of 5-HT-ergic neurotransmission are increasingly used as animal models of depression. In the present study, CVS…”
Get full text

Selective Antagonist for the Melanocortin 4 Receptor (HS014) Increases Food Intake in Free-Feeding Rats by Kask, Ants, Rägo, Lembit, Mutulis, Felikss, Pähkla, Rein, Wikberg, Jarl E.S., Schiöth, Helgi B.

“…Recently, we discovered a cyclic analogue of MSH (melanocyte stimulating hormone), HS014, which is the first selective antagonist of the MC4 receptor. We have…”
Get full text

Evidence for involvement of the melanocortin MC4 receptor in the effects of leptin on food intake and body weight by KASK, A, RÄGO, L, WIKBERG, J. E. S, SCHIÖTH, H. B

“…The hypothesis that the melanocortin MC4 receptor mediates the homeostatic effects of leptin was tested. Leptin (0.3 nmol, i.c.v.) lowered food intake at 4 and…”
Get full text

Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y 1 ‐selective antagonist BIBP3226 by Kask, Ants, Rägo, Lembit, Harro, Jaanus

Get full text

Discovery of a Novel Superpotent and Selective Melanocortin-4 Receptor Antagonist (HS024): Evaluation in Vitro and in VivoThis work was supported by grants from the Swedish Medical Research Council (04X-05957), the Swedish Society for Medical Research, and the Estonian Science Foundation (Grant 3267); the Ants ja Maria Silvere ning Sigfried Panti Mälestusstipendium Foundation (to A.K.); and the Swedish Institute (to I.M.) by Kask, Ants, Mutulis, Felikss, Muceniece, Ruta, Pähkla, Rein, Mutule, Ilze, Wikberg, Jarl E. S., Rägo, Lembit, Schiöth, Helgi B.

“…Several novel cyclic MSH analogs were synthesized, and their binding properties were tested on cells transiently expressing the human melanocortin-1 (MC1),…”
Get full text

Transgenic rat model of Huntington's disease by von Hörsten, Stephan, Schmitt, Ina, Nguyen, Huu Phuc, Holzmann, Carsten, Schmidt, Thorsten, Walther, Thomas, Bader, Michael, Pabst, Reinhard, Kobbe, Philipp, Krotova, Jana, Stiller, Detlef, Kask, Ants, Vaarmann, Annika, Rathke-Hartlieb, Silvia, Schulz, Jörg B., Grasshoff, Ute, Bauer, Ingrid, Vieira-Saecker, Ana Maria Menezes, Paul, Martin, Jones, Lesley, Lindenberg, Katrin S., Landwehrmeyer, Bernhard, Bauer, Andreas, Li, Xiao-Jiang, Riess, Olaf

“…Huntington's disease (HD) is a late manifesting neurodegenerative disorder in humans caused by an expansion of a CAG trinucleotide repeat of more than 39 units…”
Get full text

Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1‐selective antagonist BIBP3226 by Kask, Ants, Rägo, Lembit, Harro, Jaanus

“…1 Experiments were conducted to evaluate the effects of the novel non‐peptide neuropeptide Y Y1 receptor antagonist, BIBP3226…”
Get full text

Tonic inhibition of food intake during inactive phase is reversed by the injection of the melanocortin receptor antagonist into the paraventricular nucleus of the hypothalamus and central amygdala of the rat by Kask, Ants, Schiöth, Helgi B.

“…Melanocortins inhibit food intake and melanocortin 4 receptor (MC 4R) antagonists stimulate feeding behaviour. These effects may occur due to stimulation or…”
Get full text

Anxiolytic-like effect of neuropeptide Y (NPY) and NPY13-36 microinjected into vicinity of locus coeruleus in rats by Kask, A, Rägo, L, Harro, J

“…Neuropeptide Y (NPY, 1 and 10 pmol), NPY Y1 receptor agonist [Leu31, Pro34]NPY (10 pmol) and Y2 agonist NPY13-36 (100 pmol) were administered unilaterally into…”
Get full text

Anxiogenic-like effect of the neuropeptide Y Y 1 receptor antagonist BIBP3226: antagonism with diazepam by Kask, Ants, Rägo, Lembit, Harro, Jaanus

“…The effect of the novel non-peptide neuropeptide Y Y 1 receptor antagonist BIBP3226, N 2-(diphenylacetyl)- N-[(4-hydroxy-phenyl)methyl]- d-arginine amide, on…”
Get full text

Effects of partial locus coeruleus denervation and chronic mild stress on behaviour and monoamine neurochemistry in the rat by Häidkind, Riina, Eller, Marika, Harro, Maarike, Kask, Ants, Rinken, Ago, Oreland, Lars, Harro, Jaanus

“…It has been proposed that lesions of the ascending noradrenergic projections render animals more vulnerable to stress. In this study, the effects of partial…”
Get full text

NPY Y1 receptors in the dorsal periaqueductal gray matter regulate anxiety in the social interaction test by Kask, Ants, Rägo, Lembit, Harro, Jaanus

“…WE have reported previously that the NPY Y1 receptor antagonist BIBP3226 applied into the dorsal periaqueductal gray matter (DPAG) has an anxiogenic-like…”
Get full text

Neuropeptide Y Y5 receptor antagonist CGP71683A: the effects on food intake and anxiety-related behavior in the rat by KASK, Ants, VASAR, Eero, HEIDMETS, Lenne-Triin, ALLIKMETS, Lembit, WIKBERG, Jarl E. S

Get full text

α-Helical CRF9-41 prevents anxiogenic-like effect of NPY Y1 receptor antagonist BIBP3226 in rats by Kask, Ants, Rägo, Lembit, Harro, Jaanus

“…WE reported previously that the neuropeptide Y (NPY) Y1 receptor antagonist, N2-(diphenylacetyl)-N-[(4hydroxy-phenyl)methyl]-D-arginine amide (BIBP3226) has an…”
Get full text

Chronic infusion of a melanocortin receptor agonist modulates dopamine receptor binding in the rat brain by Lindblom, Jonas, Kask, Ants, Hägg, Erik, Härmark, Linda, Bergström, Lena, Wikberg, Jarl

“…Previous studies have shown that melanocortin peptides have facilitatory effects on dopaminergic neurotransmission. In the present study we tested the…”
Get full text

Anorexigenic cocaine- and amphetamine-regulated transcript peptide intensifies fear reactions in rats by Kask, Ants, Schiöth, Helgi B., Mutulis, Felikss, Wikberg, Jarl E.S., Rägo, Lembit

“…An increasing number of appetite-regulating peptides are being discovered. The list of regulators inhibiting food intake is considerably longer than that of…”
Get full text

Differential effects of melanocortin peptides on ingestive behaviour in rats: evidence against the involvement of MC3 receptor in the regulation of food intake by KASK, A, RÄGO, L, WIKBERG, J. E. S, SCHIÖTH, H. B

Get full text

Effects of melanocortin receptor ligands on ethanol intake and opioid peptide levels in alcohol-preferring AA rats by Ploj, Karolina, Roman, Erika, Kask, Ants, Hyytiä, Petri, Schiöth, Helgi B, Wikberg, Jarl E.S, Nylander, Ingrid

“…Melanocortin (MC) peptides are suggested to play a role in opiate dependence, where they antagonise the addictive properties of opiates. To further study the…”
Get full text