Search Results - "Kasinath, Vivek"

Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival by Uehara, Mayuko, Li, Xiaofei, Sheikhi, Amir, Zandi, Nooshin, Walker, Brian, Saleh, Bahram, Banouni, Naima, Jiang, Liwei, Ordikhani, Farideh, Dai, Li, Yonar, Merve, Vohra, Ishaan, Kasinath, Vivek, Orgill, Dennis P., Khademhosseini, Ali, Annabi, Nasim, Abdi, Reza

“…A primary goal in the management of burn wounds is early wound closure. The use of skin allografts represents a lifesaving strategy for severe burn patients,…”
Get full text

Simultaneous targeting of primary tumor, draining lymph node, and distant metastases through high endothelial venule-targeted delivery by Jiang, Liwei, Jung, Sungwook, Zhao, Jing, Kasinath, Vivek, Ichimura, Takaharu, Joseph, John, Fiorina, Paolo, Liss, Andrew S., Shah, Khalid, Annabi, Nasim, Joshi, Nitin, Akama, Tomoya O., Bromberg, Jonathan S., Kobayashi, Motohiro, Uchimura, Kenji, Abdi, Reza

“…Cancer patients with malignant involvement of tumor-draining lymph nodes (TDLNs) and distant metastases have the poorest prognosis. A drug delivery platform…”
Get full text

Delivery of costimulatory blockade to lymph nodes promotes transplant acceptance in mice by Zhao, Jing, Jung, Sungwook, Li, Xiaofei, Li, Lushen, Kasinath, Vivek, Zhang, Hengcheng, Movahedi, Said N, Mardini, Ahmad, Sabiu, Gianmarco, Hwang, Yoonha, Saxena, Vikas, Song, Yang, Ma, Bing, Acton, Sophie E, Kim, Pilhan, Madsen, Joren C, Sage, Peter T, Tullius, Stefan G, Tsokos, George C, Bromberg, Jonathan S, Abdi, Reza

“…The lymph node (LN) is the primary site of alloimmunity activation and regulation during transplantation. Here, we investigated how fibroblastic reticular…”
Get full text

Ischemia augments alloimmune injury through IL-6-driven CD4+ alloreactivity by Uehara, Mayuko, Solhjou, Zhabiz, Banouni, Naima, Kasinath, Vivek, Xiaqun, Ye, Dai, Li, Yilmam, Osman, Yilmaz, Mine, Ichimura, Takaharu, Fiorina, Paolo, Martins, Paulo N., Ohori, Shunsuke, Guleria, Indira, Maarouf, Omar H., Tullius, Stefan G., McGrath, Martina M., Abdi, Reza

“…Ischemia reperfusion injuries (IRI) are unavoidable in solid organ transplantation. IRI augments alloimmunity but the mechanisms involved are poorly…”
Get full text

Urine podoplanin heralds the onset of ischemia-reperfusion injury of the kidney by Kasinath, Vivek, Yilmam, Osman Arif, Uehara, Mayuko, Yonar, Merve, Jiang, Liwei, Li, Xiaofei, Qiu, Weiliang, Eskandari, Siawosh, Ichimura, Takaharu, Abdi, Reza

“…Ischemia-reperfusion injury represents one of the most common causes of acute kidney injury, a serious and often deadly condition that affects up to 20% of all…”
Get more information

Kidney-Draining Lymph Node Fibrosis Following Unilateral Ureteral Obstruction by Li, Xiaofei, Zhao, Jing, Naini, Said Movahedi, Sabiu, Gianmarco, Tullius, Stefan G, Shin, Su Ryon, Bromberg, Jonathan S, Fiorina, Paolo, Tsokos, George C, Abdi, Reza, Kasinath, Vivek

“…Although the primary organ has been the subject of intense investigation in the field of organ fibrosis over the past several decades, the presence of lymph…”
Get full text

LTβR Signaling Controls Lymphatic Migration of Immune Cells by Piao, Wenji, Kasinath, Vivek, Saxena, Vikas, Lakhan, Ram, Iyyathurai, Jegan, Bromberg, Jonathan S

“…The pleiotropic functions of lymphotoxin (LT)β receptor (LTβR) signaling are linked to the control of secondary lymphoid organ development and structural…”
Get full text

Characterization of Leptin Receptor + Stromal Cells in Lymph Node by Jiang, Liwei, Yilmaz, Mine, Uehara, Mayuko, Cavazzoni, Cecilia B, Kasinath, Vivek, Zhao, Jing, Naini, Said Movahedi, Li, Xiaofei, Banouni, Naima, Fiorina, Paolo, Shin, Su Ryon, Tullius, Stefan G, Bromberg, Jonathan S, Sage, Peter T, Abdi, Reza

“…Lymph node (LN)-resident stromal cells play an essential role in the proper functioning of LNs. The stromal compartment of the LN undergoes significant…”
Get full text

Characterization of CD41 + cells in the lymph node by Dai, Li, Uehara, Mayuko, Li, Xiaofei, LaBarre, Brenna A, Banouni, Naima, Ichimura, Takaharu, Lee-Sundlov, Melissa M, Kasinath, Vivek, Sullivan, Jade A, Ni, Heyu, Barone, Francesca, Giannini, Silvia, Bahmani, Baharak, Sage, Peter T, Patsopoulos, Nikolaos A, Tsokos, George C, Bromberg, Jonathan S, Hoffmeister, Karin, Jiang, Liwei, Abdi, Reza

“…Lymph nodes (LNs) are the critical sites of immunity, and the stromal cells of LNs are crucial to their function. Our understanding of the stromal compartment…”
Get full text

Clathrin light chain‐conjugated drug delivery for cancer by Jung, Sungwook, Jiang, Liwei, Zhao, Jing, Shultz, Leonard D., Greiner, Dale L., Bae, Munhyung, Li, Xiaofei, Ordikhani, Farideh, Kuai, Rui, Joseph, John, Kasinath, Vivek, Elmaleh, David R., Abdi, Reza

“…Targeted drug delivery systems hold the remarkable potential to improve the therapeutic index of anticancer medications markedly. Here, we report a targeted…”
Get full text

Repetitive ischemic injuries to the kidneys result in lymph node fibrosis and impaired healing by Maarouf, Omar H, Uehara, Mayuko, Kasinath, Vivek, Solhjou, Zhabiz, Banouni, Naima, Bahmani, Baharak, Jiang, Liwei, Yilmam, Osman A, Guleria, Indira, Lovitch, Scott B, Grogan, Jane L, Fiorina, Paolo, Sage, Peter T, Bromberg, Jonathan S, McGrath, Martina M, Abdi, Reza

“…The contribution of the kidney-draining lymph node (KLN) to the pathogenesis of ischemia-reperfusion injury (IRI) of the kidney and its subsequent recovery has…”
Get full text

ACTH treatment promotes murine cardiac allograft acceptance by Zhao, Jing, Jiang, Liwei, Uehara, Mayuko, Banouni, Naima, Al Dulaijan, Basmah S, Azzi, Jamil, Ichimura, Takaharu, Li, Xiaofei, Jarolim, Petr, Fiorina, Paolo, Tullius, Stefan G, Madsen, Joren C, Kasinath, Vivek, Abdi, Reza

“…Heart transplantation is the optimal therapy for patients with end-stage heart disease, but its long-term outcome remains inadequate. Recent studies have…”
Get full text

Cellular Mechanisms of Rejection of Optic and Sciatic Nerve Transplants: An Observational Study by Yonar, Merve, Uehara, Mayuko, Banouni, Naima, Kasinath, Vivek, Li, Xiaofei, Jiang, Liwei, Zhao, Jing, Bei, Fengfeng, Shin, Su Ryon, Cetrulo, Curtis L., Annabi, Nasim, Abdi, Reza

“…Organ transplantation is a standard therapeutic strategy for irreversible organ damage, but the utility of nerve transplantation remains generally unexplored,…”
Get full text

Abstract 14756: Outcomes of Cardiac Co-Morbidities in Renal Transplantation: A National Population-Based Cohort Study by Hussain, Bilal, Kasinath, Vivek, Abdi, Reza, Paul, Timir K

“…Background Cardiovascular disease (CVD) is common and associated with higher mortality in end-stage renal disease patients, but its impact on mortality from…”
Get full text

Targeted nanotherapy for kidney diseases: a comprehensive review by Sabiu, Gianmarco, Kasinath, Vivek, Jung, Sungwook, Li, Xiaofei, Tsokos, George C, Abdi, Reza

“…ABSTRACT Kidney diseases represent a major public health problem, affecting millions of people worldwide. Moreover, the treatment of kidney diseases is…”
Get full text

Intra-Organ Delivery of Nanotherapeutics for Organ Transplantation by Hussain, Bilal, Kasinath, Vivek, Madsen, Joren C, Bromberg, Jonathan, Tullius, Stefan G, Abdi, Reza

“…Targeted delivery of therapeutics through the use of nanoparticles (NPs) has emerged as a promising method that increases their efficacy and reduces their side…”
Get full text

Role of lymph node stroma and microenvironment in T cell tolerance by Saxena, Vikas, Li, Lushen, Paluskievicz, Christina, Kasinath, Vivek, Bean, Asher, Abdi, Reza, Jewell, Christopher M., Bromberg, Jonathan S.

“…Lymph nodes (LNs) are at the cross roads of immunity and tolerance. These tissues are compartmentalized into specialized niche areas by lymph node stromal…”
Get full text

The immunoregulatory roles of non-haematopoietic cells in the kidney by Tsokos, George C., Boulougoura, Afroditi, Kasinath, Vivek, Endo, Yushiro, Abdi, Reza, Li, Hao

“…The deposition of immune complexes, activation of complement and infiltration of the kidney by cells of the adaptive and innate immune systems have long been…”
Get full text

Author Correction: The immunoregulatory roles of non-haematopoietic cells in the kidney by Tsokos, George C., Boulougoura, Afroditi, Kasinath, Vivek, Endo, Yushiro, Abdi, Reza, Li, Hao

Get full text

High endothelial venules as potential gateways for therapeutics by Hussain, Bilal, Kasinath, Vivek, Ashton-Rickardt, Gabriel P., Clancy, Thomas, Uchimura, Kenji, Tsokos, George, Abdi, Reza

“…High endothelial venules (HEVs) are specialized blood vessels that support the migration of lymphocytes from the bloodstream into lymph nodes (LNs). They are…”
Get full text