Search Results - "Kashyap, Dharmendra"

Helicobacter pylori and Epstein-Barr Virus Coinfection Stimulates Aggressiveness in Gastric Cancer through the Regulation of Gankyrin by Kashyap, Dharmendra, Baral, Budhadev, Jakhmola, Shweta, Singh, Anil Kumar, Jha, Hem Chandra

“…Persistent coinfection with Helicobacter pylori and Epstein-Barr virus (EBV) promotes aggressive gastric carcinoma (GC). The molecular mechanisms underlying…”
Get full text

Oral rinses in growth inhibition and treatment of Helicobacter pylori infection by Kashyap, Dharmendra, Baral, Budhadev, Verma, Tarun Prakash, Sonkar, Charu, Chatterji, Debi, Jain, Ajay Kumar, Jha, Hem C

“…Helicobacter pylori (H. pylori) is well-known for its role in chronic gastritis and gastric cancer. Eradication of these carcinogenic bacteria from the gut is…”
Get full text

Comorbidity Assessment Is Essential During COVID-19 Treatment by Jakhmola, Shweta, Indari, Omkar, Baral, Budhadev, Kashyap, Dharmendra, Varshney, Nidhi, Das, Ayan, Chatterjee, Sayantani, Jha, Hem Chandra

“…Coronavirus disease 2019 (COVID-19) caused by SARS-CoV2 is associated with various comorbidities; cardiovascular diseases, hypertension, diabetes, liver, lung…”
Get full text

Mutational analysis of structural proteins of SARS-CoV-2 by Jakhmola, Shweta, Indari, Omkar, Kashyap, Dharmendra, Varshney, Nidhi, Das, Ayan, Manivannan, Elangovan, Jha, Hem Chandra

“…SARS-CoV-2 transmissibility is higher than that of other human coronaviruses; therefore, it poses a threat to the populated communities. We investigated…”
Get full text

Gankyrin: At the crossroads of cancer diagnosis, disease prognosis, and development of efficient cancer therapeutics by Kashyap, Dharmendra, Varshney, Nidhi, Parmar, Hamendra Singh, Jha, Hem Chandra

“…The pattern of Gankyrin expression is dynamic in response to various stimuli; it is known to be upregulated in several types of cancer. Therefore, Gankyrin…”
Get full text

Outer Membrane Vesicles: An Emerging Vaccine Platform by Kashyap, Dharmendra, Panda, Mrutyunjaya, Baral, Budhadev, Varshney, Nidhi, R, Sajitha, Bhandari, Vasundhra, Parmar, Hamendra Singh, Prasad, Amit, Jha, Hem Chandra

“…Vaccine adjuvants are substances that improve the immune capacity of a recombinant vaccine to a great extent and have been in use since the early 1900s; they…”
Get full text

Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates by Baral, Budhadev, Kashyap, Dharmendra, Varshney, Nidhi, Verma, Tarun Prakash, Jain, Ajay Kumar, Chatterji, Debi, Kumar, Vinod, Mishra, Amit, Kumar, Awanish, Jha, Hem Chandra

Get full text

Helicobacter pylori infected gastric epithelial cells bypass cell death pathway through the oncoprotein Gankyrin by Kashyap, Dharmendra, Varshney, Nidhi, Baral, Budhadev, Kandpal, Meenakshi, Indari, Omkar, Jain, Ajay Kumar, Chatterji, Debi, Kumar, Sachin, Parmar, Hamendra Singh, Sonawane, Avinash, Chandra Jha, Hem

“…H. pylori infection can lead to gastric diseases by modulating the various cellular processes such as cellular stress, apoptosis, autophagy, and metabolic…”
Get full text

Recent updates on COVID-19: A holistic review by Jakhmola, Shweta, Indari, Omkar, Kashyap, Dharmendra, Varshney, Nidhi, Rani, Annu, Sonkar, Charu, Baral, Budhadev, Chatterjee, Sayantani, Das, Ayan, Kumar, Rajesh, Jha, Hem Chandra

“…Coronaviruses are large positive-sense RNA viruses with spike-like peplomers on their surface. The Coronaviridae family's strains infect different animals and…”
Get full text

Data on differential pathogenic ability of Helicobacter pylori isolated from distinct gastric niches by Baral, Budhadev, Kashyap, Dharmendra, Varshney, Nidhi, Verma, Tarun Prakash, Jain, Ajay Kumar, Chatterji, Debi, Kumar, Vinod, Mishra, Amit, Kumar, Awanish, Jha, Hem Chandra

“…Helicobacter pylori infection is associated with various gastrointestinal diseases and gastric cancer. Our data shows the H. pylori isolates and their…”
Get full text

Repurposing of metabolic drugs and mitochondrial modulators as an emerging class of cancer therapeutics with a special focus on breast cancer by Tripathi, Versha, Jaiswal, Pooja, Sahu, Khageswar, Majumder, Shovan Kumar, Kashyap, Dharmendra, Chandra Jha, Hem, Dixit, Amit Kumar, Parmar, Hamendra Singh

“…As per facts sheet of WHO, cancer is a leading cause of mortality worldwide accounting nearly 10 million deaths in 2020. However, breast, lung, colon and…”
Get full text

Plant-derived active compounds as a potential nucleocapsid protein inhibitor of SARS-CoV-2: an in-silico study by Kashyap, Dharmendra, Roy, Rajarshi, Kar, Parimal, Jha, Hem Chandra

“…The coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2. This virus has a high mismatch repair proofreading ability due to its unique exonuclease…”
Get full text

Prediction of Rab5B inhibitors through integrative in silico techniques by Kashyap, Dharmendra, Koirala, Suman, Saini, Vaishali, Bagde, Pranit Hemant, Samanta, Sunanda, Kar, Parimal, Jha, Hem Chandra

“…Rab5B is a small monomeric G protein that regulates early endocytosis and controls signaling pathways related to cell growth, survival, and apoptosis…”
Get full text

Unraveling the Aurora kinase A and Epstein-Barr nuclear antigen 1 axis in Epstein Barr virus associated gastric cancer by Varshney, Nidhi, Murmu, Sneha, Baral, Budhadev, Kashyap, Dharmendra, Singh, Siddharth, Kandpal, Meenakshi, Bhandari, Vasundhra, Chaurasia, Anurag, Kumar, Sunil, Jha, Hem Chandra

“…Aurora kinase A (AURKA) is one of the crucial cell cycle regulators associated with gastric cancer. Here, we explored Epstein Barr Virus-induced gastric cancer…”
Get full text

Withania somnifera extract reduces gastric cancerous properties through inhibition of gankyrin in cellular milieu produced by Helicobacter pylori and Epstein Barr virus by Kashyap, Dharmendra, Roy, Rajarshi, Varshney, Nidhi, Baral, Budhadev, Bagde, Pranit Hemant, Kandpal, Meenakshi, Kumar, Sachin, Kar, Parimal, Jha, Hem Chandra

“…Helicobacter pylori and Epstein Barr virus (EBV) are group1 carcinogens and their role in Gastric cancer (GC) is well established. Previously we have shown…”
Get full text

Spectroscopic assessment of biomolecular changes in Helicobacter pylori and Epstein–Barr virus co‐infected gastric epithelial cells by Kashyap, Dharmendra, Tanwar, Manushree, Rani, Chanchal, Bagde, Pranit Hemant, Singh, Siddharth, Varshney, Nidhi, Saini, Vaishali, Mishra, Amit, Kumar, Rajesh, Jha, Hem Chandra

“…Abstract Helicobacter pylori and Epstein–Barr Virus (EBV) are Group 1 carcinogens that can enhance gastric cancer progression. Bioactive substances extracted…”
Get full text

Computational insights into VacA toxin inhibition: harnessing FDA-approved antibiotics against Helicobacter pylori by Kashyap, Dharmendra, Koirala, Suman, Roy, Rajarshi, Saini, Vaishali, Varshney, Nidhi, Bagde, Pranit Hemant, Samanta, Sunanda, Kar, Parimal, Jha, Hem Chandra

“…Cancer is a condition in which a few of the body's cells grow beyond its control and spread to other outward regions. Globally, gastric cancer (GC) is third…”
Get full text

Repurposing of gastric cancer drugs against COVID-19 by Sonkar, Charu, Doharey, Pawan Kumar, Rathore, Anuranjan Singh, Singh, Vishal, Kashyap, Dharmendra, Sahoo, Amaresh Kumar, Mittal, Nitish, Sharma, Bechan, Jha, Hem Chandra

“…Corona Virus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has become a global pandemic. Additionally, the…”
Get full text

Plant derived active compounds as potential anti SARS-CoV-2 agents: an in-silico study by Kashyap, Dharmendra, Jakhmola, Shweta, Tiwari, Deeksha, Kumar, Rajesh, Moorthy, N. S. Hari Narayana, Elangovan, Manivannan, Brás, Natércia F., Jha, Hem Chandra

“…Plants are a valued potential source of drugs for a variety of diseases and are often considered less toxic to humans. We investigated antiviral compounds that…”
Get full text

Comprehensive insight into altered host cell-signaling cascades upon Helicobacter pylori and Epstein–Barr virus infections in cancer by Kashyap, Dharmendra, Rele, Samiksha, Bagde, Pranit Hemant, Saini, Vaishali, Chatterjee, Debi, Jain, Ajay Kumar, Pandey, Rajan Kumar, Jha, Hem Chandra

“…Cancer is characterized by mutagenic events that lead to disrupted cell signaling and cellular functions. It is one of the leading causes of death worldwide…”
Get full text