Search Results - "Kashtanova, D"

Tackling APOE's structural challenges via in silico modeling in the era of neural networks: Can AlphaFold II help circumvent the problem of lacking full-length protein structure? by Mamchur, A.A., Ivanov, M.V., Matkava, L.R., Yudin, V.S., Keskinov, A.A., Yudin, S.M., Kashtanova, D.A.

“…The APOE gene, encoding apolipoprotein E, is a predictor of longevity and age-related diseases. Despite numerous genetic studies, the data on molecular…”
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Cognitive impairment in long-living adults: a genome-wide association study, polygenic risk score model and molecular modeling of the APOE protein by Kashtanova, D. A., Mamchur, A. A., Dzhumaniyazova, I. H., Ivanov, M. V., Erema, V. V., Zelenova, E. A., Yakovchik, A. Y., Gusakova, M. S., Rumyantseva, A. M., Terekhov, M. V., Matkava, L. R., Akopyan, A. A., Strazhesko, I. D., Yudin, V. S., Makarov, V. V., Kraevoy, S. A., Tkacheva, O. N., Yudin, S. M.

“…Background Cognitive impairment is an irreversible, aging-associated condition that robs people of their independence. The purpose of this study was to…”
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Molecular Dynamics Simulation of the Conformational Mobility of the Lipid-Binding Site in the Apolipoprotein E Isoforms ε2, ε3, and ε4 by Mamchur, A. A., Erema, V. V., Kashtanova, D. A., Ivanov, M. V., Yudin, V. S., Keskinov, A. A., Kraevoy, S. A., Yudin, S. M.

“…Neurodegenerative disorders, particularly Alzheimer’s disease, have become a major global healthcare issue. Despite extensive research, the molecular…”
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The phenomenon of intestinal permeability and its association with cardiovascular disease. Current status by Kashtanova, D. A., Tkacheva, O. N.

“…Changes in the intestinal permeability in various pathologies are widely discussed in the scientific community. There is still no consensus on whether high…”
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Short telomere length is associated with arterial aging in patients with type 2 diabetes mellitus by Dudinskaya, E N, Tkacheva, O N, Shestakova, M V, Brailova, N V, Strazhesko, I D, Akasheva, D U, Isaykina, O Y, Sharashkina, N V, Kashtanova, D A, Boytsov, S A

“…It is known that glucose disturbances contribute to micro- and macrovascular complications and vascular aging. Telomere length is considered to be a cellular…”
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Structure of circulatory system diseases and their genetic predictors in athletes with high intensity of training and competitive load by Zholinsky, A. V., Kadykova, A. I., Gladyshev, N. S., Terekhov, M. V., Ivashechkin, A. A., Maksyutina, V. V., Nekrasova, A. I., Mitrofanov, S. I., Ivanov, M. V., Kashtanova, D. A., Yudin, V. S., Keskinov, A. A., Yudin, S. M., Deev, R. V., Skvortsova, V. I.

“…Introduction: Morphofunctional changes of the circulatory system organs detected in athletes may remain without due attention, as clinical (phenotypic) signs…”
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New variant of PRDM16 gene nucleotide sequence in a family with various phenotypic manifestations of the non-compacted myocardium by Myasnikov, R. P., Bukaeva, A. A., Kulikova, O. V., Ershova, A. I., Petukhova, A. V., Zotova, E. D., Meshkov, A. N., Mershina, E. A., Kiseleva, A. V., Divashuk, M. G., Pilyus, P. S., Kharlap, M. S., Mikova, V. M., Koretsky, S. N., Gandaeva, L. A., Sinitsyn, V. E., Basargina, E.. N., Boytsov, S. A., Snigir, E. A., Akinshina, A. I., Kashtanova, D. A., Makarov, V. V., Yudin, V. S., Drapkina, O. M.

“…The article presents the examination of three generations of a family with diagnosed left ventricular noncompaction (LVNC) and various phenotypic…”
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GUT MICROBIOTA AND CARDIOVASCULAR RISK FACTORS. PART III. LIPID PROFILE, CARBOHYDRATE METABOLISM AND GUT MICROBIOTA by Tkacheva, O. N., Kashtanova, D. A., Boytsov, S. A.

“…Of the main significantly prevalent modifiable risk factors of cardiovascular risk are carbohydrate and lipid metabolism disorders. Recent years have shown…”
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Gut microbiota and cardiovascular risk factors. Part IV. Arterial hypertension, smoking and the gut microbiota by Kashtanova, D. A., Tkacheva, O. N., Boytsov, S. A.

“…The collected data on the interaction of human-as-host and their gut microbiota reveals new opportunities for further investigation and translation to practice…”
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THE STUDY OF LONGEVITY: RECENT UPDATES AND FURTHER DIRECTION. PART 2 by Kotovskaya, Yu. V., Tkacheva, О. N., Runikhina, N. К., Kashtanova, D. A., Boytsov, S. A.

“…Regardless the global demographic tendencies of life duration increase, longevity and super longevity remain quite understudied and non-fully understood…”
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GUT MICROBIOTA AND CARDIOVASCULAR RISK FACTORS. PART 1. GUT MICROBIOTA, AGE AND SEX by Kashtanova, D. A., Tkacheva, O. N., Boytsov, S. A.

“…The experience of the recent decade has led to ability of complex evaluation of human health, including not only external influences, genetic determinants, but…”
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GUT MICROBIOTA AND CARDIOVASCULAR RISK FACTORS. PART 2. GUT MICROBIOTA AND OBESITY by Kashtanova, D. A., Tkacheva, O. N., Boytsov, S. A.

“…The importance of adipose tissue is much greater than it has been expected. Adipose tissue is a large endocrine organ, value of which is difficult to…”
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THE STUDY OF LONGEVITY: RECENT UPDATES AND FURTHER DIRECTION. PART 1 by Kotovskaya, Yu. V., Tkacheva, О. N., Runikhina, N. К., Kashtanova, D. A., Boytsov, S. A.

“…The increase  of life duration leads to a sharp growth of the older and senile persons number. Differences in chronological and biological ages, of the…”
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GUT MICROBIOTA AND ITS RELATIONS WITH CARDIOVASCULAR RISK FACTORS IN ALMOST HEALTHY INHABITANTS OF MOSCOW AND MOSCOW REGION by Kashtanova, D. A., Tkacheva, О. N., Popenko, A. S., Tyakht, A. V., Alexeev, D. G., Kotovskaya, Yu. V., Boytsov, S. А.

“…Aim. To investigate on the relation of microbiota content  and cardiovascular  risk factors  among  persons  with no  clinical signs  of cardiovascular…”
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THE ROLE OF VITAMIN D IN THE PATHOGENESIS OF CHRONIC NON-COMMUNICABLE DISEASES by Egshatyan, L V, Dudinskaya, E N, Tkacheva, O N, Kashtanova, D A

“…This review shows the role of vitamin D in the regulation of not only the level of calcium, but also in the pathogenesis of chronic systemic inflammation,…”
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VASCULAR WALL CONDITION, GUT MICROBIOTA COMPOSITION, AND DIET IN PATIENTS WITHOUTCARDIOVASCULAR DISEASES by Kashtanova, D A, Tkacheva, O N, Egshatyan, L V, Plokhova, E V, Popenko, A S, Tyakht, A V, Alexeev, D G, Kotovskaya, Yu V, Boytsov, S А

“…Purpose of the study. To study the relationship between the gut microbiota composition, the state of the vascular wall and nutrient intake in patients without…”
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P297Gut microbiota and cardiovascular risk factors: Moscow study by Kashtanova, D A, Tkacheva, O N, Boytsov, S A

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P2251Association between low-grade inflammation, metabolic factors, vascular biomarkers and gut microbiota in different age groups by Kashtanova, D, Tkacheva, O N, Kotovskaya, Y U V, Dudinskaya, E N, Brailova, N V, Plokhova, E V, Onuchina, Y U S, Sharashkina, N V, Eruslanova, K A

“…Abstract Background Despite the growing interest to the theme, the gut microbiota (GM) composition and functional capacity in relation to cardiovascular…”
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P4419Gut microbiota composition, low-grade inflammation, and subclinical atherosclerosis in apparently healthy individuals from moscow by Kashtanova, D A, Tkacheva, O N, Kotovskaya, Y U V, Popenko, A S, Tyaht, A V, Alekseev, D G, Boytsov, S A

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A clinical case of reverse left ventricular remodeling in patient with pathogenic TTN mutation. Case report by Nasonova, S N, Meshkov, A N, Zhirov, I V, Osmolovskaya, Y F, Shoshina, A A, Gagloev, A V, Dzhumaniiazova, I H, Zelenova, E A, Erema, V V, Gusakova, M S, Ivanov, M V, Terekhov, M V, Kashtanova, D A, Nekrasova, A I, Mitrofanov, S I, Shingaliev, A S, Yudin, V S, Keskinov, A A, Gomyranova, N V, Chubykina, U V, Ezhov, M V, Tereshchenko, S N, Yudin, S M, Boytsov, S A

“…Dilated cardiomyopathy (DCM) is a leading cause of heart failure, sudden cardiac death, and heart transplantation in young patients. The causes of DCM are…”
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