Search Results - "Kashinath, K"

Physics-informed machine learning: case studies for weather and climate modelling by Kashinath, K, Mustafa, M, Albert, A, Wu, J-L, Jiang, C, Esmaeilzadeh, S, Azizzadenesheli, K, Wang, R, Chattopadhyay, A, Singh, A, Manepalli, A, Chirila, D, Yu, R, Walters, R, White, B, Xiao, H, Tchelepi, H A, Marcus, P, Anandkumar, A, Hassanzadeh, P, Prabhat

“…Machine learning (ML) provides novel and powerful ways of accurately and efficiently recognizing complex patterns, emulating nonlinear dynamics, and predicting…”
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Comprehensive Study on Solomonamides: Total Synthesis, Stereochemical Revision, and SAR Studies toward Identification of Simplified Lead by Jachak, Gorakhnath R., Kashinath, K., Vasudevan, N., Athawale, Paresh R., Choudhury, Rahul, Dange, Santoshkumar S., Agarwal, Heena, Barthwal, Manoj Kumar, Reddy, D. Srinivasa

“…Solomonamides, a pair of macrocyclic peptide natural products originating from marine sources, have garnered significant attention within the synthetic…”
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Total Synthesis of Deoxy-solomonamide B by Mimicking Biogenesis by Vasudevan, N, Kashinath, K, Reddy, D. Srinivasa

“…A total synthesis of Deoxy-solomonamide B was accomplished starting from tryptophan in an efficient manner by mimicking the proposed biogenetic route. The…”
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Total Synthesis of the Marine Natural Product Solomonamide B Necessitates Stereochemical Revision by Kashinath, K, Jachak, Gorakhnath R, Athawale, Paresh R, Marelli, Udaya Kiran, Gonnade, Rajesh G, Reddy, D. Srinivasa

“…The first total synthesis of the proposed structure of solomonamide B has been achieved. However, the 1H and 13C NMR spectral data of the synthesized compound…”
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Breaking and Making of Olefins Simultaneously Using Ozonolysis: Application to the Synthesis of Useful Building Blocks and Macrocyclic Core of Solomonamides by Kashinath, K, Dhara, Santu, Reddy, D. Srinivasa

“…A simple and practical one-pot, two-directional approach to access olefinic esters through simultaneous breaking and making of olefins using ozonolysis of…”
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Synthesis of Chiral Tetrahydrofuran Building Blocks from Pantolactones: Application in the Synthesis of Empagliflozin and Amprenavir Analogs by Athawale, Paresh R., Kumari, Neeta, Dandawate, Monica R., Kashinath, K., Srinivasa Reddy, D.

“…Chiral 4,4–dimethyl tetrahydrofuran (THF) derivatives were synthesized from commercially available D‐(–)/ l‐(+) pantolactones, which can serve as chiral…”
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Synthesis of an Oxathiolane Drug Substance Intermediate Guided by Constraint-Driven Innovation by Kashinath, K., Snead, David R., Burns, Justina M., Stringham, Rodger W., Gupton, B. Frank, McQuade, D. Tyler

“…A new route was developed for construction of the oxathiolane intermediate used in the synthesis of lamivudine (3TC) and emtricitabine (FTC). We developed the…”
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Access to a Stereoisomer Library of Solomonamide Macrocycles by Jachak, Gorakhnath R., Athawale, Paresh R., Choudhury, Rahul, Kashinath, K., Reddy, D. Srinivasa

“…In an attempt towards understanding stereo‐structure activity relationships (SSARs), we have prepared eight possible stereoisomers of solomonamide macrocycles,…”
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One-pot quadruple/triple reaction sequence: a useful tool for the synthesis of natural products by Kashinath, K, Reddy, D Srinivasa

“…Multiple reactions in one pot has always been a useful technique for synthetic organic chemists, as it can minimizes solvent usage, time and the number of…”
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Studies toward the Synthesis of Potent Anti-inflammatory Peptides Solomonamides A and B: Synthesis of a Macrocyclic Skeleton and Key Fragment 4‑Amino-6-(2′-amino-4′-hydroxyphenyl)-3-hydroxy-2-methyl-6-oxohexanoic Acid (AHMOA) by Kashinath, K, Vasudevan, N, Reddy, D. Srinivasa

“…A first synthetic effort toward total synthesis of highly potent solomonamides is disclosed. An efficient strategy to synthesize this class of compounds, along…”
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Superior laryngeal nerve block with in-line lignocaine nebulization for awake extubation response by Jadhav, Kashinath K., Karnalkar, Asmita P., Patil, Shailendra B.

“…Background and Aims: Tracheal extubation is associated with various undesirable hemodynamic and airway responses. Various drugs are used effectively to curb…”
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Total synthesis of an anticancer norsesquiterpene alkaloid isolated from the fungus Flammulina velutipes by Kashinath, K, Jadhav, Prakash D, Reddy, D Srinivasa

“…The first total synthesis of a norsesquiterpene alkaloid (R)-8-hydroxy-4,7,7-trimethyl-7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione, isolated from the…”
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Earth Virtualization Engines: A Technical Perspective by Hoefler, Torsten, Stevens, Bjorn, Prein, Andreas F., Baehr, J., Schulthess, T., Stocker, Thomas F., Taylor, John, Klocke, Daniel, Manninen, Pekka, Forster, Piers M., Kolling, Tobias, Gruber, Nicolas, Anzt, Hartwig, Frauen, Claudia, Ziemen, Flora, Klower, Milan, Kashinath, K., Schar, C., Fuhrer, Oliver, Lawrence, Bryan N.

“…Participants of the Berlin Summit on Earth Virtualization Engines (EVEs) discussed ideas and concepts to improve our ability to cope with climate change. EVEs…”
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An innovative modified feeding appliance for an infant with cleft lip and cleft palate: A case report by Naveen, B, Prasad, Raghavendra, Kashinath, K, Kumar, Shylesh, Kalavathi, S, Laishram, Narendra

“…Cleft lip and palate is one of the most common craniofacial anomalies of humans. A child born with cleft lip and palate may experience difficulties while…”
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Nosocomial infections in patients admitted in intensive care unit of a tertiary health center, India by Mythri, H, Kashinath, Kr

“…Patients in Intensive Care Units (ICUs) are a significant subgroup of all hospitalized patients, accounting for about a quarter of all hospital infections. The…”
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Discovery of Potent and Selective A2A Antagonists with Efficacy in Animal Models of Parkinson’s Disease and Depression by Basu, Sujay, Barawkar, Dinesh A, Ramdas, Vidya, Naykodi, Minakshi, Shejul, Yogesh D, Patel, Meena, Thorat, Sachin, Panmand, Anil, Kashinath, K, Bonagiri, Rajesh, Prasad, Vandna, Bhat, Ganesh, Quraishi, Azfar, Chaudhary, Sumit, Magdum, Amol, Meru, Ashwinkumar V, Ghosh, Indraneel, Bhamidipati, Ravi K, Raje, Amol A, Madgula, Vamsi L. M, De, Siddhartha, Rouduri, Sreekanth R, Palle, Venkata P, Chugh, Anita, Hariharan, Narayanan, Mookhtiar, Kasim A

“…Adenosine A2A receptor (A2AAdoR) antagonism is a nondopaminergic approach to Parkinson’s disease treatment that is under development. Earlier we had reported…”
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Enantiospecific Formal Synthesis of Inthomycin C by Athawale, Paresh R., Kashinath, K., Reddy, D. Srinivasa

“…An enantiospecific synthesis of Hatakeyama's intermediate enynol has been accomplished in both enantiomeric forms. As these intermediates can be converted to…”
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Discovery of Potent and Selective A 2A Antagonists with Efficacy in Animal Models of Parkinson's Disease and Depression by Basu, Sujay, Barawkar, Dinesh A, Ramdas, Vidya, Naykodi, Minakshi, Shejul, Yogesh D, Patel, Meena, Thorat, Sachin, Panmand, Anil, Kashinath, K, Bonagiri, Rajesh, Prasad, Vandna, Bhat, Ganesh, Quraishi, Azfar, Chaudhary, Sumit, Magdum, Amol, Meru, Ashwinkumar V, Ghosh, Indraneel, Bhamidipati, Ravi K, Raje, Amol A, Madgula, Vamsi L M, De, Siddhartha, Rouduri, Sreekanth R, Palle, Venkata P, Chugh, Anita, Hariharan, Narayanan, Mookhtiar, Kasim A

“…Adenosine A receptor (A AdoR) antagonism is a nondopaminergic approach to Parkinson's disease treatment that is under development. Earlier we had reported the…”
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Labial ankyloglossia associated with oligodontia: a case report by Chandrashekar, L, Kashinath, K R, Suhas, Setty

“…Developmental disturbances of the tongue (aglossia, macroglossia, microglossia, and ankyloglossia) can adversely affect the development of the surrounding…”
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Assessing learning preferences of dental students using visual, auditory, reading-writing, and kinesthetic questionnaire by Bennadi, Darshana, Kashinath, K, Bharateesh, J, Kshetrimayum, Nandita

“…Introduction: Educators of the health care profession (teachers) are committed in preparing future health care providers, but are facing many challenges in…”
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