Search Results - "Kashima, Hajime"
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Fibroblast activation protein targeted near infrared photoimmunotherapy (NIR PIT) overcomes therapeutic resistance in human esophageal cancer
Published in Scientific reports (18-01-2021)“…Cancer-associated fibroblasts (CAFs) have an important role in the tumor microenvironment. CAFs have the multifunctionality which strongly support cancer…”
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Cancer‐associated fibroblasts (CAFs) promote the lymph node metastasis of esophageal squamous cell carcinoma
Published in International journal of cancer (15-02-2019)“…Lymph node metastasis is a pathognomonic feature of spreading tumors, and overcoming metastasis is a challenge in attaining more favorable clinical outcomes…”
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Laparoscopic Resection Combined with a Transsacral Approach for a Recurrent Tailgut Cyst with a Refractory Fistula
Published in Acta medica Okayama (01-04-2024)“…Tailgut cyst is a rare cystic disease of the anterior sacral surface and the remains of an embryonic tail gut. Tailgut cysts have a potential for malignancy,…”
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Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma
Published in Cancer biology & therapy (02-09-2019)“…Cancer-associated fibroblasts (CAFs) are strongly implicated in tumor progression, including in the processes of tumorigenesis, invasion, and metastasis. The…”
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Dual-targeted near-infrared photoimmunotherapy for esophageal cancer and cancer-associated fibroblasts in the tumor microenvironment
Published in Scientific reports (23-11-2022)“…Cancer-associated fibroblasts (CAFs) play a significant role in tumor progression within the tumor microenvironment. Previously, we used near-infrared…”
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Laparoscopic and Endoscopic Cooperative Surgery for Gastric Submucosal Tumor Near Esophagogastric Junction With Sliding Hiatal Hernia
Published in Curēus (Palo Alto, CA) (20-04-2023)“…The usefulness of laparoscopic and endoscopic cooperative surgery (LECS) for gastric submucosal tumors in the cardiac region has been reported in recent years…”
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Epirubicin, Identified Using a Novel Luciferase Reporter Assay for Foxp3 Inhibitors, Inhibits Regulatory T Cell Activity
Published in PloS one (10-06-2016)“…Forkhead box protein p3 (Foxp3) is crucial to the development and suppressor function of regulatory T cells (Tregs) that have a significant role in…”
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Impact of cancer-associated fibroblasts on survival of patients with ampullary carcinoma
Published in Frontiers in oncology (16-03-2023)“…Cancer-associated fibroblasts (CAFs) reportedly enhance the progression of gastrointestinal surgery; however, the role of CAFs in ampullary carcinomas remains…”
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Iron depletion is a novel therapeutic strategy to target cancer stem cells
Published in Oncotarget (17-11-2017)“…Adequate iron levels are essential for human health. However, iron overload can act as catalyst for the formation of free radicals, which may cause cancer…”
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Safety of Surgical Treatment for Elderly Patients with Gallbladder Carcinoma
Published in Acta medica Okayama (01-06-2019)“…Gallbladder carcinoma (GBC) is a common malignancy with a poor prognosis. With the average life expectancy increasing globally, the incidence of GBC is…”
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Pancreatic Ductal Adenocarcinoma in Remnant Pancreas after Pancreaticoduodenectomy for Acinar Cell Carcinoma: A Case Report
Published in Journal of Nippon Medical School (15-10-2019)“…We report a case of a pancreatic ductal adenocarcinoma (PDAC) in the remnant pancreas of a 78-year-old man after pancreaticoduodenectomy for acinar cell…”
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Pancreatic Ductal Adenocarcinoma in Remnant Pancreas after Pancreaticoduodenectomy for Acinar Cell Carcinoma : A Case Report
Published in Journal of Nippon Medical School (01-10-2019)“…We report a case of a pancreatic ductal adenocarcinoma (PDAC) in the remnant pancreas of a 78-year-old man after pancreaticoduodenectomy for acinar cell…”
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Enantioselective Total Synthesis of (−)-Taxol
Published in Journal of the American Chemical Society (26-04-2000)“…Enantioselective total synthesis of taxol has been accomplished. Coupling reaction of the optically pure A-ring hydroxy aldehyde with the aromatic C-ring…”
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Prone-Position Thoracoscopic Ligation of the Thoracic Duct for Chyle Leak Following Radical Neck Dissection in a Patient with a Right Aortic Arch
Published in Acta medica Okayama (01-06-2015)“…A chyle leak can occur as a complication after neck or chest surgery. Such a leak prolongs the hospital stay and is sometimes life-threatening. The treatment…”
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Cancer-Associated Fibroblasts Affect Intratumoral CD8 + and FoxP3 + T Cells Via IL6 in the Tumor Microenvironment
Published in Clinical cancer research (01-10-2018)“…Cancer-associated fibroblasts (CAFs) in the tumor microenvironment (TME) play a central role in tumor progression. We investigated whether CAFs can regulate…”
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Therapeutic Potential of Targeting Cancer-Associated Fibroblasts in Esophageal Cancer
Published in Gan to kagaku ryoho (01-10-2015)“…Advances in molecular and cellular biochemistry, such as the development of targeted cancer therapy, have dramatically improved the prognosis of cancer…”
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Two cases of dural metastasis of breast cancer
Published in Gan to kagaku ryoho (01-11-2014)“…The first case of dural metastasis occurred in a 60s years old woman, who presented with bone metastasis to the right breast. Nine months later, disorientation…”
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