Search Results - "Kashima, Akiko"
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Machine learning to estimate the local quality of protein crystal structures
Published in Scientific reports (08-12-2021)“…Low-resolution electron density maps can pose a major obstacle in the determination and use of protein structures. Herein, we describe a novel method, called…”
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Ionic liquid-assisted sample preparation mediates sensitive proteomic analysis of Bacillus subtilis spores
Published in Scientific reports (29-07-2024)“…Endospore-forming bacteria are ubiquitous. Bacterial endospores are multilayered proteinaceous structures that protects the bacterial genome during stress…”
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Structural characterization of l-glutamate oxidase from Streptomyces sp. X-119-6
Published in The FEBS journal (01-07-2009)“…l-Glutamate oxidase (LGOX) from Streptomyces sp. X-119-6, which catalyzes the oxidative deamination of l-glutamate, has attracted increasing attention as a…”
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4
Neuropsychological and functional correlates of clock-drawing test in elderly institutionalized patients with schizophrenia
Published in Psychogeriatrics (01-12-2012)“…Background: There has been a growing need for a cognitive assessment tool that can be used for older adults with schizophrenia in clinical settings. The…”
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An ionic liquid-assisted sample preparation method for sensitive integral-membrane proteome analysis
Published in Analytical biochemistry (15-12-2023)“…Many ion channels and receptor proteins are potential targets for new drugs. However, standard methods for profiling these integral membrane proteins (IMPs)…”
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Japanese version of the Body Attitude Test: Its reliability and validity
Published in Psychiatry and clinical neurosciences (01-10-2003)“…The Body Attitude Test (BAT) was developed by Probst et al. (1995) for female patients with eating disorders (ED). This test measures the subjective body…”
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Optimization of α-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 (β5i)/LMP2 (β1i) dual inhibitor
Published in Bioorganic & medicinal chemistry (15-07-2024)“…[Display omitted] The immunoproteasome subunit LMP7 (β5i)/LMP2 (β1i) dual blockade has been reported to suppress B cell differentiation and activation,…”
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A behavior therapy program combined with liquid nutrition designed for anorexia nervosa
Published in Psychiatry and clinical neurosciences (01-10-2002)“…We have introduced behavior therapy as standard in‐patient treatment for anorexia nervosa and have modified the treatment program. At first, we used…”
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Discovery of SPH3127: A Novel, Highly Potent, and Orally Active Direct Renin Inhibitor
Published in Journal of medicinal chemistry (25-08-2022)“…Renin is the rate-limiting enzyme in the renin–angiotensin–aldosterone system (RAAS) which regulates blood pressure and renal function and hence is an…”
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The Structure of Murine N 1‑Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism
Published in Biochemistry (Easton) (24-01-2017)“…N 1-Acetylspermine oxidase (APAO) catalyzes the conversion of N 1-acetylspermine or N 1-acetylspermidine to spermidine or putrescine, respectively, with…”
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Discovery and structural analyses of S-adenosyl-l-homocysteine hydrolase inhibitors based on non-adenosine analogs
Published in Bioorganic & medicinal chemistry (01-08-2015)“…[Display omitted] Optimization of a new series of S-adenosyl-l-homocysteine hydrolase (AdoHcyase) inhibitors based on non-adenosine analogs led to very potent…”
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Discovery of Novel 2‑Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors
Published in ACS medicinal chemistry letters (11-08-2022)“…The renin–angiotensin–aldosterone system (RAAS) plays a key role in the regulation of blood pressure. Renin, the first and rate-limiting enzyme of the RAAS, is…”
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X‐ray crystal structure of a dipeptide‐chymotrypsin complex in an inhibitory interaction
Published in European journal of biochemistry (01-07-1998)“…The dipeptide D‐leucyl‐ L‐phenylalanyl p‐fluorobenzylamide ( D‐Leu‐Phe‐NH‐BzlF) inhibits chymotrypsin strongly in a competitive manner with the Ki value of…”
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15
Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 Å resolution
Published in Proteins, structure, function, and bioinformatics (01-02-2007)“…Human JNK stimulatory phosphatase‐1 (JSP‐1) is a novel member of dual specificity phosphatases. A C‐terminus truncated JSP‐1 was expressed in Escherichia coli…”
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16
The Structure of Murine N1-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism
Published in Biochemistry (Easton) (24-01-2017)“…N1-Acetylspermine oxidase (APAO) catalyzes the conversion of N1-acetylspermine or N1-acetylspermidine to spermidine or putrescine, respectively, with…”
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Aromatase Inhibitors : Synthesis, Biological Activity, and Structure of 1, 2-Imidazolylmethylcyclopentanol Derivatives
Published in Chemical & pharmaceutical bulletin (1995)“…Two series of 1, 2-disubstituted imidazolylmethylcyclopentanol derivatives (5a-d, 10a-d) were prepared by using easily available metyl…”
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18
Structural characterization ofl-glutamate oxidase from Streptomyces sp. X-119-6
Published in The FEBS journal (01-07-2009)“…l-Glutamate oxidase (LGOX) from Streptomyces sp. X-119-6, which catalyzes the oxidative deamination ofl-glutamate, has attracted increasing attention as a…”
Get full text
Journal Article -
19
Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 Aa resolution
Published in Proteins, structure, function, and bioinformatics (01-01-2007)“…Human JNK stimulatory phosphatase-1 (JSP-1) is a novel member of dual specificity phosphatases. A C-terminus truncated JSP-1 was expressed in Escherichia coli…”
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Psychogenic depression
Published in Ryoikibetsu shokogun shirizu (2003)Get more information
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