Search Results - "Kasher, Jeffrey S"

Structure-activity relationship within a series of pyrazolidinone antibacterial agents. 2. Effect of side-chain modification on in vitro activity and pharmacokinetic parameters by Ternansky, Robert J, Draheim, Susan E, Pike, Andrew J, Counter, Fred T, Eudaly, Judy A, Kasher, Jeffrey S

“…The structure-activity relationship among a series of novel pyrazolidinone antibacterial agents is described. Specifically, the effect of modification of the…”
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Synthesis and anaerobic activity of novel 1-carba-1-dethiacephalosporins by Ternansky, Robert J, Jordan, Christopher L, Eudaly, Judy A, Kasher, Jeffrey S

“…The synthesis and biological evaluation of novel 1-carba-1-dethiacephalosporins exhibiting activity against anaerobic pathogens are described. The…”
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The synthesis and biological characteristics of new orally active cephems by Ternansky, R J, Jordan, C L, Bell, F W, Skaggs, T G, Kasher, J S

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C(3)-cyclopropyl cephems and carbacephems by Spry, D O, Snyder, N J, Kasher, J S

“…A series of C(3)-cyclopropyl cephems and carbacephems has been prepared by palladium catalyzed addition of diazomethane to the corresponding C(3)-vinyl…”
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Discovery and structure-activity relationship of a series of 1-carba-1-dethiacephems exhibiting activity against methicillin-resistant Staphylococcus aureus by Ternansky, Robert J, Draheim, Susan E, Pike, Andrew J, Bell, F. William, West, Sarah J, Jordan, Christopher L, Wu, C. Y. Ernie, Preston, David A, Alborn, William

“…The synthesis and antimicrobial activity of several new 1-carba-1-dethiacephalosporins is described. The discovery of unique activity of some of the analogues…”
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Synthesis and biological evaluation of a series of parenteral 3'-quaternary ammonium cephalosporins by Brown, Raymond F, Kinnick, Michael D, Morin, John M, Vasileff, Robert T, Counter, Fred T, Davidson, Edward O, Ensminger, Paul W, Eudaly, Judith A, Kasher, Jeffrey S

“…The preparation and biological evaluation of a series of 7 beta-[2-(2-aminothiazol-4-yl)-2(Z)-methoximinoacetamido]cep halosporins, substituted at the…”
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3-Quaternary ammonium 1-carba-1-dethiacephems by Cook, Gwendolyn K., McDonald, John H., Alborn, William, Boyd, Donald B., Eudaly, Judy A., Indelicato, Joseph M., Johnson, Rod, Kasher, Jeffrey S., Pasini, Carol E.

“…A series of structurally unique 1-carba-1-dethiacephems is described. The structural stability of the 1-carba-1-dethiacephem nucleus was essential for the…”
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