Search Results - "Kashaf, Sara Saheb"

Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functions by Saheb Kashaf, Sara, Proctor, Diana M., Deming, Clay, Saary, Paul, Hölzer, Martin, Taylor, Monica E., Kong, Heidi H., Segre, Julia A., Almeida, Alexandre, Finn, Robert D.

“…Human skin functions as a physical barrier to foreign pathogen invasion and houses numerous commensals. Shifts in the human skin microbiome have been…”
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Smart Bandages: The Future of Wound Care by Derakhshandeh, Hossein, Kashaf, Sara Saheb, Aghabaglou, Fariba, Ghanavati, Ian O., Tamayol, Ali

“…Chronic non-healing wounds are major healthcare challenges that affect a noticeable number of people; they exert a severe financial burden and are the leading…”
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Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids by Schuster, Brooke, Junkin, Michael, Kashaf, Sara Saheb, Romero-Calvo, Isabel, Kirby, Kori, Matthews, Jonathan, Weber, Christopher R., Rzhetsky, Andrey, White, Kevin P., Tay, Savaş

“…Three-dimensional (3D) cell culture technologies, such as organoids, are physiologically relevant models for basic and clinical applications. Automated…”
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Adding Fuel to the Fire? The Skin Microbiome in Atopic Dermatitis by Saheb Kashaf, Sara, Kong, Heidi H

“…Atopic dermatitis (AD) is a multifactorial, heterogeneous disease characterized by epidermal barrier dysfunction, immune system dysregulation, and skin…”
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Recovering prokaryotic genomes from host-associated, short-read shotgun metagenomic sequencing data by Saheb Kashaf, Sara, Almeida, Alexandre, Segre, Julia A., Finn, Robert D.

“…Recovering genomes from shotgun metagenomic sequence data allows detailed taxonomic and functional characterization of individual species or strains in a…”
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Development of hydrogels for regenerative engineering by Guan, Xiaofei, Avci‐Adali, Meltem, Alarçin, Emine, Cheng, Hao, Kashaf, Sara Saheb, Li, Yuxiao, Chawla, Aditya, Jang, Hae Lin, Khademhosseini, Ali

“…The aim of regenerative engineering is to restore complex tissues and biological systems through convergence in the fields of advanced biomaterials, stem cell…”
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OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics by Matthews, Jonathan M, Schuster, Brooke, Kashaf, Sara Saheb, Liu, Ping, Ben-Yishay, Rakefet, Ishay-Ronen, Dana, Izumchenko, Evgeny, Shen, Le, Weber, Christopher R, Bielski, Margaret, Kupfer, Sonia S, Bilgic, Mustafa, Rzhetsky, Andrey, Tay, Savaş

“…Organoids have immense potential as ex vivo disease models for drug discovery and personalized drug screening. Dynamic changes in individual organoid…”
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Staphylococcal diversity in atopic dermatitis from an individual to a global scale by Saheb Kashaf, Sara, Harkins, Catriona P., Deming, Clay, Joglekar, Payal, Conlan, Sean, Holmes, Cassandra J., Almeida, Alexandre, Finn, Robert D., Segre, Julia A., Kong, Heidi H.

“…Atopic dermatitis (AD) is a multifactorial, chronic relapsing disease associated with genetic and environmental factors. Among skin microbes, Staphylococcus…”
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Making life difficult for Clostridium difficile: augmenting the pathogen's metabolic model with transcriptomic and codon usage data for better therapeutic target characterization by Kashaf, Sara Saheb, Angione, Claudio, Lió, Pietro

“…Clostridium difficile is a bacterium which can infect various animal species, including humans. Infection with this bacterium is a leading…”
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Risk factors of lower limb cellulitis in a level-two healthcare facility in Cameroon: a case-control study by Njim, Tsi, Aminde, Leopold Ndemnge, Agbor, Valirie Ndip, Toukam, Louise Daniele, Kashaf, Sara Saheb, Ohuma, Eric O

“…Cellulitis is a common infection of the skin and subcutaneous tissues. It is associated with significant morbidity from necrosectomies and amputations…”
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A mouse model of occult intestinal colonization demonstrating antibiotic-induced outgrowth of carbapenem-resistant Enterobacteriaceae by Sim, Choon K, Kashaf, Sara Saheb, Stacy, Apollo, Proctor, Diana M, Almeida, Alexandre, Bouladoux, Nicolas, Chen, Mark, Finn, Robert D, Belkaid, Yasmine, Conlan, Sean, Segre, Julia A

“…The human intestinal microbiome is a complex community that contributes to host health and disease. In addition to normal microbiota, pathogens like…”
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Systemic mastocytosis, in the context of a deleterious germline SDHC variant, treated with ripretinib by Saheb Kashaf, Sara, Godley, Lucy A., Chadha, Angad, Waldinger, Jason B.

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Drug delivery systems and materials for wound healing applications by Saghazadeh, Saghi, Rinoldi, Chiara, Schot, Maik, Kashaf, Sara Saheb, Sharifi, Fatemeh, Jalilian, Elmira, Nuutila, Kristo, Giatsidis, Giorgio, Mostafalu, Pooria, Derakhshandeh, Hossein, Yue, Kan, Swieszkowski, Wojciech, Memic, Adnan, Tamayol, Ali, Khademhosseini, Ali

“…Chronic, non-healing wounds place a significant burden on patients and healthcare systems, resulting in impaired mobility, limb amputation, or even death…”
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Ocular adhesives: Design, chemistry, crosslinking mechanisms, and applications by Trujillo-de Santiago, Grissel, Sharifi, Roholah, Yue, Kan, Sani, Ehsan Shrizaei, Kashaf, Sara Saheb, Alvarez, Mario Moisés, Leijten, Jeroen, Khademhosseini, Ali, Dana, Reza, Annabi, Nasim

“…Closure of ocular wounds after an accident or surgery is typically performed by suturing, which is associated with numerous potential complications, including…”
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Integrated genomic and functional analyses of human skin-associated Staphylococcus reveal extensive inter- and intra-species diversity by Joglekar, Payal, Conlan, Sean, Lee-Lin, Shih-Queen, Deming, Clay, Kashaf, Sara Saheb, Kong, Heidi H, Segre, Julia A

“…Human skin is stably colonized by a distinct microbiota that functions together with epidermal cells to maintain a protective physical barrier. , a prominent…”
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A genome catalog of the early-life human skin microbiome by Shen, Zeyang, Robert, Lukian, Stolpman, Milan, Che, You, Allen, Katrina J, Saffery, Richard, Walsh, Audrey, Young, Angela, Eckert, Jana, Deming, Clay, Chen, Qiong, Conlan, Sean, Laky, Karen, Li, Jenny Min, Chatman, Lindsay, Kashaf, Sara Saheb, Kong, Heidi H, Frischmeyer-Guerrerio, Pamela A, Perrett, Kirsten P, Segre, Julia A

“…Metagenome-assembled genomes have greatly expanded the reference genomes for skin microbiome. However, the current reference genomes are largely based on…”
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Recreating composition, structure, functionalities of tissues at nanoscale for regenerative medicine by Alarçin, Emine, Guan, Xiaofei, Kashaf, Sara Saheb, Elbaradie, Khairat, Yang, Huazhe, Jang, Hae Lin, Khademhosseini, Ali

“…Nanotechnology offers significant potential in regenerative medicine, specifically with the ability to mimic tissue architecture at the nanoscale. In this…”
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Expanded microbiome niches of RAG-deficient patients by Blaustein, Ryan A., Shen, Zeyang, Kashaf, Sara Saheb, Lee-Lin, ShihQueen, Conlan, Sean, Thomas, Jim, Mullikin, James, Young, Alice, Bouffard, Gerry, Barnabas, Betty, Brooks, Shelise, Buchter, Chloe, Crawford, Juyun, Han, Joel, Ho, Shi-ling, Legaspi, Richelle, Maduro, Quino, Marfani, Holly, Montemayor, Casandra, Schandler, Karen, Schmidt, Brian, Sison, Christina, Stantripop, Mal, Black, Sean, Dekhtyar, Mila, Masiello, Cathy, McDowell, Jenny, Park, Morgan, Thomas, Pam, Vemulapalli, Meg, Bosticardo, Marita, Delmonte, Ottavia M., Holmes, Cassandra J., Taylor, Monica E., Banania, Glenna, Nagao, Keisuke, Dimitrova, Dimana, Kanakry, Jennifer A., Su, Helen, Holland, Steven M., Bergerson, Jenna R.E., Freeman, Alexandra F., Notarangelo, Luigi D., Kong, Heidi H., Segre, Julia A.

“…The complex interplay between microbiota and immunity is important to human health. To explore how altered adaptive immunity influences the microbiome, we…”
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Systemic mastocytosis, in the context of a deleterious germline SDHC variant, treated with ripretinib by Saheb Kashaf, Sara, Godley, Lucy A, Chadha, Angad, Waldinger, Jason B

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