Search Results - "Kasel, D"

Pharmacokinetics of inhaled colistin in patients with cystic fibrosis by Ratjen, F., Rietschel, E., Kasel, D., Schwiertz, R., Starke, K., Beier, H., van Koningsbruggen, S., Grasemann, H.

“…Objectives: Inhaled colistin is commonly used in patients with cystic fibrosis (CF), but only limited data are available to define its pharmacokinetic profile…”
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EFFECT OF PROPIVERINE ON CYTOCHROME P450 ENZYMES: A COCKTAIL INTERACTION STUDY IN HEALTHY VOLUNTEERS by Tomalik-Scharte, D, Jetter, A, Kinzig-Schippers, M, Skott, A, Sörgel, F, Klaassen, T, Kasel, D, Harlfinger, S, Doroshyenko, O, Frank, D, Kirchheiner, J, Bräter, M, Richter, K, Gramatté, T, Fuhr, U

“…The present study was conducted to assess a possible in vivo effect of propiverine, an anticholinergic drug to treat urinary incontinence and related…”
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Screening for inhibitory effects of antineoplastic agents on CYP3A4 in human liver microsomes by Baumhäkel, M, Kasel, D, Rao-Schymanski, R A, Böcker, R, Beckurts, K T, Zaigler, M, Barthold, D, Fuhr, U

“…The human cytochrome P450 enzyme CYP3A4 is involved in the metabolism of many anticancer drugs. Since these drugs are usually administered in a…”
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Individual pharmacokinetics play a major role in toxicity of the BEACOPP polychemotherapy regimen in Hodgin's disease by Wilde, S., Jetter, A., Rietbrock, S., Kasel, D., Sieber, M., Tesch, H., Hempel, G., Reif, S., Jaehde, U., Merkel, U., Busse, D., Schwab, M., Diehl, V., Fuhr, U.

“…Background/Aims The BEACOPP chemotherapy regimen (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone) used for…”
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Semi-mechanistic Pharmacokinetic/Pharmacodynamic Modelling of the Antinociceptive Response in the Presence of Competitive Antagonism: The Interaction Between Tramadol and its Active Metabolite on μ-Opioid Agonism and Monoamine Reuptake Inhibition, in the Rat by Beier, Horst, Garrido, María J., Christoph, Thomas, Kasel, Dirk, Trocóniz, Iñaki F.

“…Purpose To establish a semi-mechanistic pharmacokinetic/pharmacodynamic (pk/pd) model for racemic tramadol (T) integrating all the components with a…”
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Population pharmacokinetics of the BEACOPP polychemotherapy regimen in Hodgkin's lymphoma and its effect on myelotoxicity by WILDE, Stefan, JETTER, Alexander, MERKEL, Ute, BUSSE, Dagmar, SCHWAB, Matthias, DIEHL, Volker, FUHR, Uwe, RIETBROCK, Stephan, KASEL, Dirk, ENGERT, Andreas, JOSTING, Andreas, KLIMM, Beate, HEMPEL, Georg, REIF, Stefanie, JAEHDE, Ulrich

“…The BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine and prednisone) chemotherapy regimen for the treatment of advanced…”
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Cytochrome P 450 2C9 phenotyping using low-dose tolbutamide by Jetter, Alexander, Kinzig-Schippers, Martina, Skott, Andreas, Lazar, Andreas, Tomalik-Scharte, Dorota, Kirchheiner, Julia, Walchner-Bonjean, Monika, Hering, Ursula, Jakob, Verena, Rodamer, Michael, Jabrane, Wafa, Kasel, Dirk, Brockm ller, J rgen, Fuhr, Uwe, S rgel, Fritz

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Quantification of cyclophosphamide and its metabolites in urine using liquid chromatography/tandem mass spectrometry by Kasel, Dirk, Jetter, Alexander, Harlfinger, Steffi, Gebhardt, Wilhelm, Fuhr, Uwe

“…A reliable and easy to use liquid chromatography/tandem mass spectrometry (LC/MS/MS) method was developed for the simultaneous quantification of urinary…”
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Quantification of mephenytoin and its metabolites 4′-hydroxymephenytoin and nirvanol in human urine using a simple sample processing method by Klaassen, Tobias, Kasel, Dirk, Harlfinger, Stefanie, Fuhr, Uwe

“…A reliable and easy to use liquid chromatography/tandem mass spectrometry (LC/MS/MS) method without the use of sample extraction was developed for the…”
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Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity by Klaassen, Tobias, Jetter, Alexander, Tomalik-Scharte, Dorota, Kasel, Dirk, Kirchheiner, Julia, Jaehde, Ulrich, Fuhr, Uwe

“…Objectives (S)-Mephenytoin is selectively metabolised to (S)-4′-hydroxymephenytoin by CYP2C19. The urinary excretion of 4′-hydroxymephenytoin reflects the…”
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Application of Balloon-Expandable Transcatheter Heart Valve in Bicuspid Aortic Valve by Chen, Mi, Michel, Jonathan, Kasel, Albert Markus

“…Bicuspid aortic valve (BAV) remains challenging in transcatheter aortic valve replacement (TAVR) because of unfavorable anatomy. New-generation…”
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Bending the Rules in Transfemoral TAVI With the SAPIEN 3: Overcoming Severe Iliac Tortuosity by Michel, Jonathan, MBBS, Frangieh, Antonio H., MD, Ott, Ilka, MD, Kasel, A.M., MD

“…Whilst the worldwide uptake of transcatheter aortic valve implantation (TAVI) over the last 10 years has been dramatic, iliac tortuosity remains a potential…”
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Successful Transapical Implantation of an Edwards Sapien Valve Within an Insufficient Aortic CoreValve Prosthesis: An Initial Experience by Schleger, Simone, MD, Kasel, Markus, MD, Vogel, Jayshree, MS, Lieber, Michael, MD, Antoni, Dietmar, MD, Hoffmann, Ellen, MD, PhD, Eichinger, Walter B., MD, PhD

“…Transcatheter aortic valve implantation (TAVI) has become an emerging alternative for high-risk patients with aortic stenosis unsuitable for surgical…”
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