Search Results - "Kasaoka, Tatsuhiko"

Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis by Yamaura, Takeshi, Kasaoka, Tatsuhiko, Iijima, Naoko, Kimura, Masaaki, Hatakeyama, Shinji

“…Therapeutic effects of focal adhesion kinase (FAK) inhibition using a small molecule inhibitor was evaluated in apolipoprotein E (apoE) knockout (KO) and…”
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The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site by Ishihara, Katsuya, Tsutsumi, Kae, Kawane, Shiho, Nakajima, Motowo, Kasaoka, Tatsuhiko

“…The receptor for advanced glycation end-products (RAGE)-mediated cellular activation through the mitogen-activated protein kinase (MAPK) cascade, activation of…”
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Heparanase-mediated cleavage of macromolecular heparin accelerates release of granular components of mast cells from extracellular matrices by Higashi, Nobuaki, Waki, Michihiko, Sue, Mayumi, Kogane, Yusuke, Shida, Hiroaki, Tsunekawa, Naoki, Hasan, Ahasanul, Sato, Takeshi, Kitahara, Ayumi, Kasaoka, Tatsuhiko, Hayakawa, Yoshihiro, Nakajima, Motowo, Irimura, Tatsuro

“…Heparanase cleaves macromolecular heparin in the secretory granules of connective tissue-type mast cells. We investigated roles of the cleavage under a…”
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Matrix metalloproteinase inhibitor, MMI270 (CGS27023A) inhibited hematogenic metastasis of B16 melanoma cells in both experimental and spontaneous metastasis models by Kasaoka, Tatsuhiko, Nishiyama, Hiroko, Okada, Mikiko, Nakajima, Motowo

“…Matrix metalloproteinases (MMP) have been implicated in several steps of tumor metastasis, such as invasion in the extracellular matrix, intravasation,…”
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Silencing of focal adhesion kinase by tumor direct injection of small interfering RNA decreases in vivo tumor growth by Tsutsumi, Kae, Yamaura, Takeshi, Nakajima, Motowo, Honda, Toshiyuki, Kasaoka, Tatsuhiko

“…Focal adhesion kinase (FAK) is shown to be frequently correlated with malignancy of the tumor and poor prognosis of the diseases. Because FAK resides…”
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Heparanase expression in B16 melanoma cells and peripheral blood neutrophils before and after extravasation detected by novel anti-mouse heparanase monoclonal antibodies by Komatsu, Noriko, Waki, Michihiko, Sue, Mayumi, Tokuda, Chikashi, Kasaoka, Tatsuhiko, Nakajima, Motowo, Higashi, Nobuaki, Irimura, Tatsuro

“…Degradation of extracellular matrix is associated with extravasation of metastatic tumor cells and inflammatory cells. Heparanase, the heparan sulfate-specific…”
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Human breast adenocarcinoma (MDA-231) and human lung squamous cell carcinoma (Hara) do not have the ability to cause bone resorption by themselves during the establishment of bone metastasis by Tomita, Amy, Kasaoka, Tatsuhiko, Inui, Takashi, Toyoshima, Minako, Nishiyama, Hiroko, Saiki, Hiromasa, Iguchi, Haruo, Nakajima, Motowo

“…Osteolysis is an important process in the establishment of bone metastasis. The role which cancer cells play in this process is not fully understood. In this…”
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Identification of genes responsible for cell migration by a library of randomized ribozymes by SUYAMA, Eigo, KAWASAKI, Hiroaki, KASAOKA, Tatsuhiko, TAIRA, Kazunari

“…Several genes appear to be associated with metastasis, but the underlying mechanisms of metastasis still remain unclear. In this study, we used a library of…”
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Tumor growth inhibition by synthetic and expressed siRNA targeting focal adhesion kinase by TSUTSUMI, Kae, KASAOKA, Tatsuhiko, PARK, Hyi-Man, NISHIYAMA, Hiroko, NAKAJIMA, Motowo, HONDA, Toshiyuki

“…Focal adhesion kinase (FAK) was first identified as a viral Src substrate, and substantial experimental data have significantly correlated the elevated FAK…”
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Molecular analysis of structural protein genes of the Yamagata-1 strain of defective subacute sclerosing panencephalitis virus. I. Nucleotide sequence of the nucleoprotein gene by Komase, K, Kasaoka, T, Yoshikawa, Y, Sato, T A, Yamanouchi, K

“…The complete nucleotide sequence of cloned cDNAs corresponding to the full-length mRNA encoding the NP protein of the Yamagata-1 strain of subacute sclerosing…”
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Identification of feline herpesvirus type 1-hemagglutinin by Horimoto, T, Kasaoka, T, Tuchiya, K, Takahashi, E

“…The crude hemagglutinin of feline herpesvirus type 1 (FHV-1), solubilized from infected fcwf-4 cells by detergents, was partially purified by three kinds of…”
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An improved method for hemagglutinin extraction from feline herpesvirus type 1-infected cell line by Horimoto, T, Kasaoka, T, Tuchiya, K, Takahashi, E

“…Hemagglutination (HA) activity of feline herpesvirus type 1 (FHV-1) propagated in feline lung cell culture and two established feline cell lines, CRFK and…”
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Plaque assay for canine coronavirus in CRFK cells by Tuchiya, K, Kasaoka, T, Azetaka, M, Takahashi, E, Konishi, S

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