Search Results - "Kasamoto, Sawako"

Comprehensive evaluation of the flavonol anti-oxidants, alpha-glycosyl isoquercitrin and isoquercitrin, for genotoxic potential by Hobbs, Cheryl A., Koyanagi, Mihoko, Swartz, Carol, Davis, Jeffrey, Kasamoto, Sawako, Maronpot, Robert, Recio, Leslie, Hayashi, Shim-mo

“…Quercetin and its glycosides possess potential benefits to human health. Several flavonols are available to consumers as dietary supplements, promoted as…”
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In vivo genotoxicity study of titanium dioxide nanoparticles using comet assay following intratracheal instillation in rats by Naya, Masato, Kobayashi, Norihiro, Ema, Makoto, Kasamoto, Sawako, Fukumuro, Masahito, Takami, Shigeaki, Nakajima, Madoka, Hayashi, Makoto, Nakanishi, Junko

“…► Genotoxicity of TiO2 nanoparticles was evaluated in vivo using a comet assay. ► TiO2 NPs were instilled intratracheally single or once a week for 5weeks to…”
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Reference control data obtained from an in vivo comet-micronucleus combination assay using Sprague Dawley rats by Kasamoto, Sawako, Masumori, Shoji, Tanaka, Jin, Ueda, Maya, Fukumuro, Masahito, Nagai, Miho, Yamate, Jyoji, Hayashi, Makoto

“…According to the International Conference on Harmonization Guidance on Genotoxicity Testing and Data Interpretation for Pharmaceuticals Intended for Human Use…”
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An international validation study of a Bhas 42 cell transformation assay for the prediction of chemical carcinogenicity by Sakai, Ayako, Sasaki, Kiyoshi, Hayashi, Kumiko, Muramatsu, Dai, Arai, Shoko, Endou, Nobuko, Kuroda, Sachiko, Poth, Albrecht, Bohnenberger, Susanne, Kunkelmann, Thorsten, Asakura, Masumi, Hirose, Hideki, Ishii, Nana, Mizuhashi, Fukutaro, Kasamoto, Sawako, Nagai, Miho, Pant, Kamala, Bruce, Shannon W., Sly, Jamie E., Yamazaki, Shojiro, Umeda, Makoto, Tanaka, Noriho

“…► Bhas 42 cell transformation assay is a sensitive short-term system. ► Six laboratories from three countries participate. ► Twelve coded chemicals are…”
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Safety evaluation of arabinase (arabinan endo‐1,5‐α‐L‐arabinanase) from Aspergillus tubingensis by Okado, Nobuo, Sugi, Mai, Kasamoto, Sawako, Mizuhashi, Fukutaro, Roberts, Ashley, Danielewska‐Nikiel, Barbara, Sulaiman, Christina, Pham, Sa

“…Arabinase is an enzyme recognized for its ability to degrade arabinan, a plant cell wall constituent. It has been applied in the food industry most commonly…”
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Analysis of negative historical control group data from the in vitro micronucleus assay using TK6 cells by Lovell, David P., Fellows, Mick, Marchetti, Francesco, Christiansen, Joan, Elhajouji, Azeddine, Hashimoto, Kiyohiro, Kasamoto, Sawako, Li, Yan, Masayasu, Ozaki, Moore, Martha M., Schuler, Maik, Smith, Robert, Stankowski, Leon F., Tanaka, Jin, Tanir, Jennifer Y., Thybaud, Veronique, Van Goethem, Freddy, Whitwell, James

“…•Historical negative controls are important for data quality and interpretation.•13 laboratories’ data on TK6 cells for in vitro micronucleus were analysed…”
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Flow cytometric analysis of micronuclei in rat peripheral blood: An interlaboratory reproducibility study by Kasamoto, Sawako, Mukai, Daisuke, Masumori, Shoji, Suzuki, Kenichiro, Tanaka, Ryota, Torous, Dorothea K., Yamate, Jyoji, Hayashi, Makoto

“…•High interlaboratory reproducibility of data collected by FCM was confirmed.•Good correlation of %MNRET analyzed by microscopy and FCM was shown.•The…”
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In vivo micronucleus assay in mouse bone marrow and peripheral blood by Kasamoto, Sawako, Masumori, Shoji, Hayashi, Makoto

“…The rodent micronucleus assay has been most widely and frequently used as a representative in vivo assay system to assess mutagenicity of chemicals, regardless…”
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