Search Results - "Kasaian, M. T"

Proteomic analysis of serum and sputum analytes distinguishes controlled and poorly controlled asthmatics by Kasaian, M. T., Lee, J., Brennan, A., Danto, S. I., Black, K. E., Fitz, L., Dixon, A. E.

“…Summary Background A major goal of asthma therapy is to achieve disease control, with maintenance of lung function, reduced need for rescue medication, and…”
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Activation-induced cellular accumulation of histamine in immature but not mature murine mast cells by Fitz, L. J, Brennan, A, Wood, C. R, Goldman, S. J, Kasaian, M. T

“…Mast cell activation involves the rapid release of inflammatory mediators, including histamine, from intracellular granules. The cells are capable of…”
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A novel and sensitive ELISA reveals that the soluble form of IL-13R-α2 is not expressed in plasma of healthy or asthmatic subjects by O'Toole, M., Legault, H., Ramsey, R., Wynn, T. A., Kasaian, M. T.

“…Summary Background IL‐13 plays a key regulatory role in asthmatic responses and immunity to parasitic infection. In vivo, IL‐13R‐α2 is a critical modulator of…”
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Identification and analysis of a novel human surface CD5- B lymphocyte subset producing natural antibodies by Kasaian, MT, Ikematsu, H, Casali, P

“…The production of "natural" autoantibodies or antibodies, i.e., Ig that bind a variety of self- and/or exogenous Ag and arise independently of known…”
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Comparison of the levels of the major allergens Der p I and Der p II in standardized extracts of the house dust mite, Dermatophagoides pteronyssinus by Meyer, C H, Bond, J F, Chen, M S, Kasaian, M T

“…Allergy to the house dust mite Dermatophagoides pteronyssinus is mediated by IgE to the major allergens Der p I and Der p II in the majority of mite-allergic…”
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IL-21 Limits NK Cell Responses and Promotes Antigen-Specific T Cell Activation: A Mediator of the Transition from Innate to Adaptive Immunity by Kasaian, Marion T, Whitters, Matthew J, Carter, Laura L, Lowe, Leslie D, Jussif, Jason M, Deng, Bijia, Johnson, Kaley A, Witek, JoAnn S, Senices, Mayra, Konz, Richard F, Wurster, Andrea L, Donaldson, Debra D, Collins, Mary, Young, Deborah A, Grusby, Michael J

“…IFNα/β, IL-12, and IL-15 regulate NK cell activation and expansion, but signals triggering resolution of the NK response upon induction of adaptive immunity…”
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Interleukin 2-induced proliferation of murine natural killer cells in vivo by BIRON, C. A, YOUNG, H. A, KASAIAN, M. T

“…The growth factor, IL-2, was administered to mice to evaluate the in vivo responsiveness of NK cells to this factor. The immediate effects of this factor on NK…”
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Structure of the VH and VL segments of monoreactive and polyreactive IgA autoantibodies to DNA in patients with systemic lupus erythematosus by Kasaian, MT, Ikematsu, H, Balow, JE, Casali, P

“…Anti-DNA IgA autoantibodies play an important immunopathologic role in SLE patients. To analyze the cellular origin and the VH and VL structure of anti-DNA IgA…”
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Structural analysis of the VH-D-JH segments of human polyreactive IgG mAb. Evidence for somatic selection by Ikematsu, H, Kasaian, MT, Schettino, EW, Casali, P

“…Polyreactive (natural) antibodies are primarily IgM and account for a major proportion of circulating Ig in humans. They use various V gene segments, in…”
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Autoimmunity-prone B-1 (CD5 B) cells, natural antibodies and self recognition by Kasaian, M T, Casali, P

“…The delineation of distinct subsets committed to the production of antibodies with different antigen-binding activities supports the view of a…”
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An increased frequency of IgE-producing B cell precursors contributes to the elevated levels of plasma IgE in atopic subjects by Kasaian, M T, Meyer, C H, Nault, A K, Bond, J F

“…The production of specific IgE, which underlies the allergic response, may be a normal correlate of the immune response to a certain class of antigen…”
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CD5+ B lymphocytes by Kasaian, M T, Ikematsu, H, Casali, P

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The activation of IL-2 transcription in L3T4+ and Lyt-2+ lymphocytes during virus infection in vivo by Kasaian, MT, Biron, CA

“…During infection of mice with lymphocytic choriomeningitis virus (LCMV), activation and proliferation of NK cells occurs early, followed by the activation and…”
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Internalization of nerve growth factor by PC12 cells. A description of cellular pools by Kasaian, M T, Neet, K E

“…Binding and internalization of nerve growth factor (NGF) by responsive cells is a complex process. We have incubated rat pheochromocytoma cells (PC12) with…”
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The major dog allergens, Can f 1 and Can f 2, are salivary lipocalin proteins: cloning and immunological characterization of the recombinant forms by KONIECZNY†, A., MORGENSTERN‡, J. P., BIZINKAUSKAS, C. B., LILLEY, C. H., BRAUER§, A. W., BOND, J. F., AALBERSE, R. C., WALLNER, B. P., KASAIAN, M. T.

“…Canis familiaris allergen 1 (Can f 1) and Canis familiaris allergen 2 (Can f 2) are the two major allergens present in dog dander extracts. We now report the…”
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Effects of cyclosporin A on IL-2 production and lymphocyte proliferation during infection of mice with lymphocytic choriomeningitis virus by Kasaian, MT, Biron, CA

“…The immunosuppressive agent, cyclosporin A (CsA) blocks production of IL-2 by lymphocytes in vitro, and impairs immune responses in vivo. During infection of…”
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The role of CD4+ cells in sustaining lymphocyte proliferation during lymphocytic choriomeningitis virus infection by Kasaian, MT, Leite-Morris, KA, Biron, CA

“…The murine immune response to lymphocytic choriomeningitis virus (LCMV) infection involves the activation of CD8+, class I MHC-restricted and virus-specific…”
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Cytokine priming of human basophils: description of allergen 'nonreleasers' by Black, K M, Lussier, A M, Gion, W R, Kasaian, M T

“…Interleukins 3 and 5 and GM-CSF enhance histamine release from basophils triggered by various stimuli. In this report, we describe a subset of allergic…”
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Flow cytometric analysis of fluorescein-labeled nerve growth factor binding to A875 human melanoma cells by Kasaian, M T, Jacobberger, J W, Neet, K E

“…The interaction of fluorescein-labeled nerve growth factor (NGF) with human melanoma cells (A875) has been studied in order to assess better methodology for…”
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Natural autoantibodies by Chai, S K, Mantovani, L, Kasaian, M T, Casali, P

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