Search Results - "Kasai, Kikuo"

Liraglutide, a GLP-1 receptor agonist, inhibits vascular smooth muscle cell proliferation by enhancing AMP-activated protein kinase and cell cycle regulation, and delays atherosclerosis in ApoE deficient mice by Jojima, Teruo, Uchida, Kohsuke, Akimoto, Kazumi, Tomotsune, Takanori, Yanagi, Kazunori, Iijima, Toshie, Suzuki, Kunihiro, Kasai, Kikuo, Aso, Yoshimasa

“…Several studies have demonstrated that both native glucagon-like peptide-1 (GLP-1) and GLP-1 receptor agonists suppress the progression of atherosclerosis in…”
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Globular Adiponectin Activates Nuclear Factor-κB and Activating Protein-1 and Enhances Angiotensin II–Induced Proliferation in Cardiac Fibroblasts by HATTORI, Yoshiyuki, HATTORI, Sachiko, AKIMOTO, Kazumi, NISHIKIMI, Toshio, SUZUKI, Kunihiro, MATSUOKA, Hiroaki, KASAI, Kikuo

“…Globular Adiponectin Activates Nuclear Factor-κB and Activating Protein-1 and Enhances Angiotensin II–Induced Proliferation in Cardiac Fibroblasts Yoshiyuki…”
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Anti-Inflammatory Role of Cilostazol in Vascular Smooth Muscle Cells In vitro and In vivo by Aoki, Chie, Hattori, Yoshiyuki, Tomizawa, Atsuko, Jojima, Teruo, Kasai, Kikuo

“…Aim: Cilostazol is a selective inhibitor of phosphodiesterase 3, by which it increases intracellular cAMP and activates protein kinase A, thereby inhibiting…”
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Telmisartan inhibits cytokine-induced nuclear factor-κB activation independently of the peroxisome proliferator-activated receptor-γ by Nakano, Ayuko, Hattori, Yoshiyuki, Aoki, Chie, Jojima, Teruo, Kasai, Kikuo

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Fluvastatin upregulates endothelial nitric oxide synthase activity via enhancement of its phosphorylation and expression and via an increase in tetrahydrobiopterin in vascular endothelial cells by Aoki, Chie, Nakano, Ayuko, Tanaka, Seiichi, Yanagi, Kazunori, Ohta, Satoshi, Jojima, Teruo, Kasai, Kikuo, Takekawa, Hidehiro, Hirata, Koichi, Hattori, Yoshiyuki

“…Abstract Background An HMG-CoA reductase inhibitor, fluvastatin, appears to act directly on the blood vessel wall to stabilize plaques in situ, agents that…”
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Lipopolysaccharide activates Akt in vascular smooth muscle cells resulting in induction of inducible nitric oxide synthase through nuclear factor-kappa B activation by Hattori, Yoshiyuki, Hattori, Sachiko, Kasai, Kikuo

“…Bacterial lipopolysaccharide and other immunostimulants induce gene expression of an isoform of nitric oxide synthase (iNOS) in vascular smooth muscle cells…”
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Fixed-dose combination of alogliptin/pioglitazone improves glycemic control in Japanese patients with type 2 diabetes mellitus independent of body mass index by Aoki, Chie, Suzuki, Kunihiro, Kuroda, Hisamoto, Sagara, Masaaki, Shimizu, Masanori, Kasai, Kikuo, Aso, Yoshimasa

“…This study investigated the effects of switching from combination therapy with either alogliptin (Alo) or pioglitazone (Pio) to fixed-dose combination therapy…”
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HMG-CoA Reductase Inhibitor Increases GTP Cyclohydrolase I mRNA and Tetrahydrobiopterin in Vascular Endothelial Cells by Hattori, Yoshiyuki, Nakanishi, Nobuo, Akimoto, Kazumi, Yoshida, Mika, Kasai, Kikuo

“…OBJECTIVE—Endothelial nitric oxide synthase (eNOS) activity is supported by tetrahydrobiopterin (BH4), which appears to be important for generating protective…”
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Vascular Smooth Muscle Cell Activation by Glycated Albumin (Amadori Adducts) by Hattori, Yoshiyuki, Suzuki, Manabu, Hattori, Sachiko, Kasai, Kikuo

“…Nonenzymatic glycation is increased in diabetes. The role of advanced glycation end products has been implicated in many of the complications of diabetes,…”
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Comparative study between high-dose fluvastatin and low-dose fluvastatin and ezetimibe with regard to the effect on endothelial function in diabetic patients by Kawagoe, Yoshiaki, Hattori, Yoshiyuki, Nakano, Ayuko, Aoki, Chie, Tanaka, Seiichi, Ohta, Satoshi, Iijima, Toshie, Tomizawa, Atsuko, Jojima, Teruo, Kase, Hiroyuki, Kasai, Kikuo

“…It is well established that statins improve the prognosis of patients with coronary artery disease. However, it is still unclear whether the protective effects…”
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The diagnosis and treatment of myxedema coma by Aoki, Chie, Kasai, Kikuo

“…Myxedema coma is defined as severe hypothyroidism leading to decreased mental status, hypothermia, and other symptoms related to dysfunction in multiple…”
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The use and problems of diagnostic guidelines for thyroid diseases by Kasai, Kikuo

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Effects of twice-daily injections of premixed insulin analog on glycemic control in type 2 diabetic patients by Shimizu, Hiroaki, Monden, Tsuyoshi, Matsumura, Mihoko, Domeki, Nozomi, Kasai, Kikuo

“…Premixed insulin is effective to improve glycemic control; however, clinicians may be less likely to know which premixed insulin is appropriate for which…”
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Liraglutide increases 24-h heart rate by reducing the cardiac parasympathetic activity of patients with type 2 diabetes: power spectral analysis of heart rate variability on 24-h Holter ECG recordings by Hara, Kenji, Aso, Yoshimasa, Komatsu, Takaaki, Nakamachi, Takafumi, Sakai, Yoshihiko, Takayanagi, Kan, Kasai, Kikuo, Inukai, Toshihiko

“…The effects of liraglutide, a glucagon-like peptide 1 receptor agonist, on heart rate over a 24-h period (24-h heart rate) and on parasympathetic modulation of…”
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A Case of Myeloma with Hypercalcemia Caused by High Serum Concentrations of both Parathyroid Hormone-related Peptide (PTHrP) and Macrophage Inflammatory Protein-1α (MIP-1α) by Shimizu, Hiroaki, Monden, Tsuyoshi, Tomotsune, Takanori, Nakatani, Yuki, Domeki, Nozomi, Matsumura, Mihoko, Jojima, Teruo, Kawagoe, Yoshiaki, Kasai, Kikuo

“…A 62-year-old woman was admitted with dry mouth, general fatigue, and severe back pain. Biochemistry examination showed extreme hypercalcemia (21.2 mg/dL)…”
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A Novel Splice Variant of the Nuclear Coactivator p120 Functions Strongly for Androgen Receptor: Characteristic Expression in Prostate Disease by HOSOYA, Takeshi, MONDEN, Tsuyoshi, FUKABORI, Yoshitatsu, HASHIMOTO, Koshi, SATOH, Teturou, KASAI, Kikuo, YAMADA, Masanobu, MORI, Masatomo

“…We cloned a novel splicing variant for nuclear coactivator p120(α), designated as p120β and studied its function and expression in several human prostate…”
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Troglitazone Upregulates Nitric Oxide Synthesis in Vascular Smooth Muscle Cells by Hattori, Yoshiyuki, Hattori, Sachiko, Kasai, Kikuo

“…We investigated the effects of troglitazone on cytokine-stimulated nitric oxide (NO) production in cultured rat vascular smooth muscle cells (VSMC). The…”
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An ACTH-secreting Pituitary Adenoma Within the Sphenoid Sinus by Suzuki, Kunihiro, Hattori, Yoshiyuki, Aoki, Chie, Nakano, Ayuko, Tomizawa, Atsuko, Kase, Hiroyuki, Kasai, Kikuo

“…A 68-year-old woman developed Cushingoid features three months prior to admission. She was found to have a markedly elevated plasma ACTH-cortisol level…”
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A Case of Myeloma with Hypercalcemia Caused by High Serum Concentrations of both Parathyroid Hormone-related Peptide (PTHrP) and Macrophage Inflammatory Protein-1.ALPHA. (MIP-1.ALPHA.) by Shimizu, Hiroaki, Monden, Tsuyoshi, Tomotsune, Takanori, Nakatani, Yuki, Domeki, Nozomi, Matsumura, Mihoko, Jojima, Teruo, Kawagoe, Yoshiaki, Kasai, Kikuo

“…A 62-year-old woman was admitted with dry mouth, general fatigue, and severe back pain. Biochemistry examination showed extreme hypercalcemia (21.2 mg/dL)…”
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Herbal Medicine, Hachimi-jio-gan, and Its Component Cinnamomi Cortex Activate the Peroxisome Proliferator-activated Receptor Alpha in Renal Cells by MONDEN, Tsuyoshi, HOSOYA, Takeshi, NAKAJIMA, Yasuyo, KISHI, Mikiko, SATOH, Teturou, HASHIMOTO, Koshi, KASAI, Kikuo, YAMADA, Masanobu, MORI, Masatomo

“…Hachimi-jio-gan is widely used to improve several disorders associated with diabetes, but its mechanism remains poorly understood. In an attempt to clarify the…”
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