Search Results - "Kas, Martien J. H"
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Intranasal mesenchymal stem cell treatment for neonatal brain damage: long-term cognitive and sensorimotor improvement
Published in PloS one (03-01-2013)“…Mesenchymal stem cell (MSC) administration via the intranasal route could become an effective therapy to treat neonatal hypoxic-ischemic (HI) brain damage. We…”
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The aperiodic exponent of neural activity varies with vigilance state in mice and men
Published in PloS one (09-08-2024)“…Recently the 1/f signal of human electroencephalography has attracted attention, as it could potentially reveal a quantitative measure of neural excitation and…”
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Comprehensive analysis of genetic risk loci uncovers novel candidate genes and pathways in the comorbidity between depression and Alzheimer’s disease
Published in Translational psychiatry (11-06-2024)“…There is growing evidence of a shared pathogenesis between Alzheimer’s disease and depression. Therefore, we aimed to further investigate their shared disease…”
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The neurobiology of repetitive behavior: …and men
Published in Neuroscience and biobehavioral reviews (01-01-2011)“…In young, typically developing children, repetitive behavior similar to that in certain neuropsychiatric syndromes is common. Whereas this behavior is adaptive…”
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The neurobiology of repetitive behavior: Of mice
Published in Neuroscience and biobehavioral reviews (01-01-2011)“…Repetitive and stereotyped behavior is a prominent element of both animal and human behavior. Similar behavior is seen across species, in diverse…”
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Hyperactivity in anorexia nervosa: warming up not just burning-off calories
Published in PloS one (27-07-2012)“…Excessive physical activity is a common feature in Anorexia Nervosa (AN) that interferes with the recovery process. Animal models have demonstrated that…”
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A New Intervention for Implementation of Pharmacogenetics in Psychiatry: A Description of the PSY-PGx Clinical Study
Published in Pharmaceuticals (Basel, Switzerland) (2024)“…Pharmacological treatment for psychiatric disorders has shown to only be effective in about one-third of patients, as it is associated with frequent treatment…”
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Autistic-like behavioural and neurochemical changes in a mouse model of food allergy
Published in Behavioural brain research (15-03-2014)“…•Food allergy in mice reduced social behaviour, increased repetitive behaviour and impaired spatial memory.•Abnormalities of the serotonergic system in the…”
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Fibroblast Growth Factors in Neurodevelopment and Psychopathology
Published in The Neuroscientist (Baltimore, Md.) (01-10-2013)“…In psychiatric disorders, the effect of genetic and environmental factors may converge on molecular pathways and brain circuits related to growth factor…”
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Modeling the quantitative nature of neurodevelopmental disorders using Collaborative Cross mice
Published in Molecular autism (13-12-2018)“…Animal models for neurodevelopmental disorders (NDD) generally rely on a single genetic mutation on a fixed genetic background. Recent human genetic studies…”
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The human neuropsychiatric risk gene Drd2 is necessary for social functioning across evolutionary distant species
Published in Molecular psychiatry (01-02-2024)“…The Drd2 gene, encoding the dopamine D 2 receptor (D2R), was recently indicated as a potential target in the etiology of lowered sociability (i.e., social…”
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Influencing cognitive performance via social interactions: a novel therapeutic approach for brain disorders based on neuroanatomical mapping?
Published in Molecular psychiatry (01-01-2023)“…Many psychiatric and neurological disorders present deficits in both the social and cognitive domain. In this perspectives article, we provide an overview and…”
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Limited impact of Cntn4 mutation on autism-related traits in developing and adult C57BL/6J mice
Published in Journal of neurodevelopmental disorders (02-03-2016)“…Mouse models offer an essential tool to unravel the impact of genetic mutations on autism-related phenotypes. The behavioral impact of some important candidate…”
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Differential Genetic Regulation of Motor Activity and Anxiety-Related Behaviors in Mice Using an Automated Home Cage Task
Published in Behavioral neuroscience (01-08-2008)“…Traditional behavioral tests, such as the open field test, measure an animal's responsiveness to a novel environment. However, it is generally difficult to…”
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Behavioral, physiological, and molecular differences in response to dietary restriction in three inbred mouse strains
Published in American journal of physiology: endocrinology and metabolism (01-09-2006)“…Food restriction paradigms are widely used in animal studies to investigate systems involved in energy regulation. We have observed behavioral, physiological,…”
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Evaluation of variation in preclinical electroencephalographic (EEG) spectral power across multiple laboratories and experiments: An EQIPD study
Published in PloS one (29-10-2024)“…The European Quality In Preclinical Data (EQIPD) consortium was born from the fact that publications report challenges with the robustness, rigor, and/or…”
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Influence of transgenic corticotropin-releasing factor (CRF) over-expression on social recognition memory in mice
Published in Behavioural brain research (15-04-2011)“…We examined juvenile social recognition and discrimination in mice with early post-natal onset, transgenic CRF over-expression (CRF-OE) and in their wild-type…”
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A template and tutorial for preregistering studies using passive smartphone measures
Published in Behavior research methods (07-08-2024)“…Passive smartphone measures hold significant potential and are increasingly employed in psychological and biomedical research to capture an individual's…”
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Models and methods: a perspective of the impact of six IMI translational data-centric initiatives for Alzheimer's disease and other neuropsychiatric disorders
Published in Frontiers in neurology (13-07-2023)“…The Innovative Medicines Initiative (IMI), was a European public-private partnership (PPP) undertaking intended to improve the drug development process,…”
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Hippocampal gene expression analysis highlights Ly6a/Sca-1 as candidate gene for previously mapped novelty induced behaviors in mice
Published in PloS one (06-06-2011)“…In this study, we show that the covariance between behavior and gene expression in the brain can help further unravel the determinants of neurobehavioral…”
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