Search Results - "Karvonen, A. M."
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Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy
Published in Allergy (Copenhagen) (01-03-2013)“…Background Genetic susceptibility and environmental influences are important contributors to the development of asthma and atopic diseases. Epigenetic…”
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Exposure to microbial agents in house dust and wheezing, atopic dermatitis and atopic sensitization in early childhood: a birth cohort study in rural areas
Published in Clinical and experimental allergy (01-08-2012)“…Summary Background Early‐life exposure to environmental microbial agents may be associated with development of wheezing and allergic diseases. Objective To…”
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Farm Environment During Pregnancy and Childhood and Polysensitization at the Age of 31: Prospective Birth Cohort Study in Finland
Published in Journal of investigational allergology & clinical immunology (01-01-2021)“…The farm environment, especially contact with farm animals in early childhood, may prevent allergic sensitization during adulthood. However, prospective…”
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Green areas around homes reduce atopic sensitization in children
Published in Allergy (Copenhagen) (01-02-2015)“…Background Western lifestyle is associated with high prevalence of allergy, asthma and other chronic inflammatory disorders. To explain this association, we…”
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Perfluoroalkyl acids and their precursors in floor dust of children's bedrooms – Implications for indoor exposure
Published in Environment international (01-10-2018)“…We analysed floor dust samples from 65 children's bedrooms in Finland collected in 2014/2015 for 62 different per- and polyfluoroalkyl substances (PFASs) with…”
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Quantity and diversity of environmental microbial exposure and development of asthma: a birth cohort study
Published in Allergy (Copenhagen) (01-08-2014)“…Background Early‐life exposure to environmental microbial agents may be associated with the development of allergies. The aim of the study was to identify…”
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Exposure to a farm environment is associated with T helper 1 and regulatory cytokines at age 4.5 years
Published in Clinical and experimental allergy (01-01-2016)“…Summary Background Farm exposure has been shown to protect from childhood asthma and allergic diseases, but underlying immunological mechanisms are not clear…”
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Microbial growth in building material samples and occupants’ health in severely moisture‐damaged homes
Published in Indoor air (01-03-2018)“…There is no commonly approved approach to detect and quantify the health‐relevant microbial exposure in moisture‐damaged buildings. In 39 single‐family homes…”
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Skin prick tests and specific IgE in 10‐year‐old children: Agreement and association with allergic diseases
Published in Allergy (Copenhagen) (01-09-2017)“…Background Accurate assessment of atopic sensitization is pivotal to clinical practice and research. Skin prick test (SPT) and specific IgE (sIgE) are often…”
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Microbial secondary metabolites in homes in association with moisture damage and asthma
Published in Indoor air (01-06-2016)“…We aimed to characterize the presence of microbial secondary metabolites in homes and their association with moisture damage, mold, and asthma development…”
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Moisture damage in home associates with systemic inflammation in children
Published in Indoor air (01-06-2016)“…This study investigated the association between confirmed moisture damage in homes and systemic subclinical inflammation in children. Home inspections were…”
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Early age exposure to moisture damage and systemic inflammation at the age of 6 years
Published in Indoor air (01-05-2018)“…Cross‐sectional studies have shown that exposure to indoor moisture damage and mold may be associated with subclinical inflammation. Our aim was to determine…”
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Circulating Dendritic Cells, Farm Exposure and Asthma at Early Age
Published in Scandinavian journal of immunology (01-01-2016)“…Farm environment has been shown to protect from childhood asthma. Underlying immunological mechanisms are not clear yet, including the role of dendritic cells…”
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Serum vitamin E concentrations at 1 year and risk of atopy, atopic dermatitis, wheezing, and asthma in childhood: the PASTURE study
Published in Allergy (Copenhagen) (01-01-2014)“…Background Prospective studies investigating the role of serum vitamin E concentrations during early life in the development of childhood allergies and asthma…”
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Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta‐analysis of European, North American and Australian cohorts
Published in BJOG : an international journal of obstetrics and gynaecology (01-07-2019)“…Objective To assess the separate and combined associations of maternal pre‐pregnancy body mass index (BMI) and gestational weight gain with the risks of…”
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Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis
Published in PLoS medicine (11-02-2019)“…Maternal obesity and excessive gestational weight gain may have persistent effects on offspring fat development. However, it remains unclear whether these…”
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Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis of 229,000 singleton births
Published in PLoS medicine (01-08-2020)“…Fetal smoke exposure is a common and key avoidable risk factor for birth complications and seems to influence later risk of overweight. It is unclear whether…”
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Early-life respiratory tract infections and the risk of school-age lower lung function and asthma: a meta-analysis of 150 000 European children
Published in The European respiratory journal (01-10-2022)“…Early-life respiratory tract infections might affect chronic obstructive respiratory diseases, but conclusive studies from general populations are lacking. Our…”
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Efficacy of human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in European infants: randomised, double-blind controlled study
Published in The Lancet (British edition) (24-11-2007)“…Summary Background We aimed to assess the efficacy of the oral live attenuated human rotavirus vaccine Rotarix (RIX4414) for prevention of rotavirus…”
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