Search Results - "Karve, Kunal"
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PIAS1 and TIF1γ collaborate to promote SnoN SUMOylation and suppression of epithelial–mesenchymal transition
Published in Cell death and differentiation (01-01-2021)“…SUMO E3 ligases specify protein substrates for SUMOylation. The SUMO E3 ligases PIAS1 and TIF1γ target the transcriptional regulator SnoN for SUMOylation…”
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Regulation of epithelial-mesenchymal transition and organoid morphogenesis by a novel TGFβ-TCF7L2 isoform-specific signaling pathway
Published in Cell death & disease (25-08-2020)“…Alternative splicing contributes to diversification of gene function, yet consequences of splicing on functions of specific gene products is poorly understood…”
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Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway
Published in PloS one (30-07-2019)“…Metastasis is the major cause of cancer-related morbidity and mortality. The ability of cancer cells to become invasive and migratory contribute significantly…”
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Correction: PIAS1 and TIF1γ collaborate to promote SnoN SUMOylation and suppression of epithelial–mesenchymal transition
Published in Cell death and differentiation (18-08-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons
Published in F1000 research (01-01-2015)“…Molecular diagnostics has changed the way lung cancer patients are treated worldwide. Of several different testing methods available, PCR followed by directed…”
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6
Abstract PO-077: High-throughput 3D-spheroid invasion assay: A powerful tool to identify novel drugs targeting tumor micro-environment in HNSCC
Published in Clinical cancer research (15-09-2023)“…Abstract Cancer metastasis is a complex cascade that involves activation of cancer cell invasion and migration. This activation is greatly attributed by…”
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The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness
Published in Oncotarget (28-03-2017)“…Tumor metastasis profoundly reduces the survival of breast cancer patients, but the mechanisms underlying breast cancer invasiveness and metastasis are…”
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Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1–NDRG1 axis in both PR-positive and -negative breast cancer cells
Published in The Journal of biological chemistry (14-12-2018)“…Preoperative progesterone intervention has been shown to confer a survival benefit to breast cancer patients independently of their progesterone receptor (PR)…”
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Recombinant human PRG4 suppresses breast cancer cell invasion by inhibiting TGF[beta]-Hyaluronan-CD44 signalling pathway
Published in PloS one (30-07-2019)“…Metastasis is the major cause of cancer-related morbidity and mortality. The ability of cancer cells to become invasive and migratory contribute significantly…”
Get full text
Journal Article -
10
Recombinant human PRG4
Published in PloS one (30-07-2019)“…Metastasis is the major cause of cancer-related morbidity and mortality. The ability of cancer cells to become invasive and migratory contribute significantly…”
Get full text
Journal Article -
11
CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons: Rapid way to detect
Published in F1000 research (08-03-2016)“…Molecular diagnostics has changed the way lung cancer patients are treated worldwide. Of several different testing methods available, PCR followed by directed…”
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12
CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons: Rapid way to detect EGFR and KRAS mutations
Published in F1000 research (01-01-2015)Get full text
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13
CRE: a cost effective and rapid approach for PCR-mediated concatenation of KRAS and EGFR exons [version 1; peer review: 1 approved, 1 approved with reservations]
Published in F1000 research (2015)“…Molecular diagnostics has changed the way lung cancer patients are treated worldwide. Of several different testing methods available, PCR followed by directed…”
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