Search Results - "Karthikeyan, Subramani"
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Are ceramic implant-supported single crowns clinically better than metal-ceramic implant-supported single crowns?
Published in Evidence-based dentistry (2021)“…Data sources Data was collected from six databases (Medline, Embase, Web of Science, The Cochrane Central Register of Controlled Trials [CENTRAL], China…”
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Magnetic Resonance Imaging Tracking of Stem Cells in Vivo Using Iron Oxide Nanoparticles as a Tool for the Advancement of Clinical Regenerative Medicine
Published in Chemical reviews (09-02-2011)“…The use of stem cells in regenerative medicine is examined. Magnetic techniques combined with nanoparticles can be used to monitor the regeneration potential…”
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Understanding the binding information of 1-imino-1,2-dihydropyrazino[1,2-a]indol-3(4H)-one in bovine serum albumin, 5-hydroxytryptamine receptor 1B and human carbonic anhydrase I: A biophysical approach
Published in Journal of molecular liquids (15-04-2020)“…The present study was focused on understanding the binding interaction mechanism of a newly synthesized 1-imino-1,2-dihydropyrazino[1,2-a]indol-3(4H)-one(PI)…”
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A pilot study on parallel factor analysis as a diagnostic tool for oral cancer diagnosis: A statistical modeling approach
Published in Journal of chemometrics (01-03-2021)“…Excitation‐emission matrix (EEM) has been extensively used as the comprehensive diagnostic tool to extract the biochemical fingerprint of the intrinsic…”
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Efficient synthesis of imino-1,3-thiazinan-4-one promoted by acetonitrile electrogenerated base and computational studies with CB1 and 11 βHSD1 molecules
Published in Research on chemical intermediates (01-12-2020)“…A novel and convenient strategy is described for the conversion of N , N ′-disubstituted thioureas and acryloyl chloride into the highly biologically valuable…”
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Synthesis, biological activity and molecular modeling of a new series of condensed 1,2,4-triazoles
Published in Bioorganic chemistry (01-11-2019)“…[Display omitted] •Synthesis of a new series of condensed 1,2,4-triazole derivatives.•Structures are characterized using NMR spectroscopy and…”
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Catalytic, Theoretical, and Biological Investigations of Ternary Metal (II) Complexes Derived from L-Valine-Based Schiff Bases and Heterocyclic Bases
Published in Molecules (Basel, Switzerland) (24-03-2023)“…A new series of ternary metal complexes, including Co(II), Ni(II), Cu(II), and Zn(II), were synthesized and characterized by elemental analysis and diverse…”
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Synthesis, crystal structure investigation, Hirshfeld and DFT studies of newly synthesized dihydroisoquinoline derivatives
Published in Arabian journal of chemistry (01-11-2023)“…Isoquinoline and its derivatives, which constitute an important category of heterocyclic compounds and are found in a variety of naturally occurring alkaloids,…”
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Determination on the binding of thiadiazole derivative to human serum albumin: a spectroscopy and computational approach
Published in Journal of biomolecular structure & dynamics (12-03-2017)“…4-[3-acetyl-5-(acetylamino)-2,3-dihydro-1,3,4-thiadiazole-2-yl]phenyl benzoate from the family of thiadiazole derivative has been newly synthesized. It has…”
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MOFs for next-generation cancer therapeutics through a biophysical approach-a review
Published in Frontiers in bioengineering and biotechnology (13-06-2024)“…Metal-organic frameworks (MOFs) have emerged as promising nanocarriers for cancer treatment due to their unique properties. Featuring high porosity, extensive…”
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Microwave-Assisted Synthesis of Fluorescent Pyrido[2,3- b ]indolizines from Alkylpyridinium Salts and Enaminones
Published in Molecules (Basel, Switzerland) (05-09-2020)“…Pyridinium ylides are well recognized as dipoles for cycloaddition reactions. In its turn, the microwave-assisted interaction of…”
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Novel 3-chloro-6-nitro-1H-indazole derivatives as promising antileishmanial candidates: synthesis, biological activity, and molecular modelling studies
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2022)“…An efficient pathway was disclosed for the synthesis of 3-chloro-6-nitro-1H-indazole derivatives by 1,3-dipolar cycloaddition on dipolarophile compounds 2 and…”
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Understanding the binding interaction mechanism of i-motif with fluorophores: A biophysical approach
Published in Chemical physics impact (01-12-2023)“…DNA exists in many canonical and non-canonical forms. i-motif: a non-canonical, tetraplex, antiparallel strand rich in cytosine, formed by hemi protonated…”
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Synthesis, crystal structure investigation, and theoretical approaches to discover potential 6-bromo-3-cyanocoumarin as a potent inhibitor MetAP (methionine aminopeptidase) 2
Published in Chemical physics impact (01-06-2024)“…•A 6-bromo-3-cyanocoumarin is synthesized and single crystal XRD showed that the asymmetric unit contained two molecules that are independent relative to…”
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Synthesis, Crystal Growth, and Computational Investigation of New Tetrahydroisoquinoline Derivatives Potent against Molecule Nitric Oxide Synthases
Published in Crystals (Basel) (01-08-2023)“…In the present work, we describe the synthesis of new tetrahydroisoquinoline derivatives and the crystal structures of two of them. Density functional theory…”
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A biophysical approach of cytarabine anticancer drug insights into human serum albumin and checkpoint kinase 1
Published in Results in Chemistry (01-01-2023)“…The present studies used biophysical techniques to examine the binding interaction mechanism of cytarabine anticancer drugs with human serum albumin (HSA) and…”
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In vitro evaluation of antimicrobial activity of chlorhexidine hexametaphosphate nanoparticle coatings on orthodontic elastomeric chains
Published in Materials research express (01-07-2020)“…This study was conducted to evaluate antimicrobial activity of orthodontic elastomeric chains (OECs) coated with chlorhexidine (CHX) hexametaphosphate (HMP)…”
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Synthesis, Crystal Structure, Hirshfeld Surface Analysis, and Computational Approach of a New Pyrazolo[3,4‑g]isoquinoline Derivative as Potent against Leucine-Rich Repeat Kinase 2 (LRRK2)
Published in ACS omega (16-07-2024)“…Ethyl-2-((8-cyano-3,5,9a-trimethyl-1-(4-oxo-4,5-dihydrothiazol-2-yl)-4-phenyl-3a,4,9,9a-tetrahydro-1H-pyrazolo[3,4-g]isoquinolin-7-yl)thio)acetate (5) was…”
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Novel peptide inhibitors targeting CD40 and CD40L interaction: A potential for atherosclerosis therapy
Published in Current research in structural biology (2023)“…Atherosclerosis is a chronic inflammatory disease characterized by plaque build-up in the arteries, leading to the obstruction of blood flow. Macrophages are…”
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Homophtalonitrile for Multicomponent Reactions: Syntheses and Optical Properties of o‐Cyanophenyl‐ or Indol‐3‐yl‐Substituted Chromeno[2,3‐c]isoquinolin‐5‐Amines
Published in ChemistryOpen (Weinheim) (01-01-2019)“…Malononitrile is a useful reagent for multicomponent reactions with hundreds of methods developed. In this paper, we suggest α‐(cyano)‐o‐tolunitrile…”
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