Search Results - "Karten, Yashmin"
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Stress in early life inhibits neurogenesis in adulthood
Published in Trends in neurosciences (Regular ed.) (01-04-2005)“…Both structure and function of the hippocampus are altered by stress: by increasing levels of corticosteroids, stress causes atrophy of CA3 pyramidal cell…”
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GABAergic signaling in young granule cells in the adult rat and mouse dentate gyrus
Published in Hippocampus (2006)“…Throughout most of the developing brain, including the hippocampus, GABAergic synapses are the first to become functional. Several features of GABAergic…”
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Towards a standardized pipeline for tau PET analysis under a GAAIN/LONI and CPAD collaborative framework
Published in Alzheimer's & dementia (01-12-2023)“…Background Imaging tau burden in vivo using Positron Emission Tomography (PET) has tremendous potential for advancing our biological understanding of…”
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Development of Clinical Trial Simulation Tools for Alzheimer’s Disease through the Critical Path for Alzheimer’s Disease (CPAD) Consortium
Published in Alzheimer's & dementia (01-12-2023)“…Background Optimized clinical trial design remains a major challenge in drug development for Alzheimer’s Disease AD). To advance our understanding of the…”
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Development of Clinical Trial Simulation Tools for Alzheimer’s Disease through the Critical Path for Alzheimer’s Disease (CPAD) Consortium
Published in Alzheimer's & dementia (01-12-2022)“…Background Critical Path Institute (C‐Path) coordinates the Critical Path for Alzheimer’s Disease (CPAD) Consortium. To accelerate DRUG DEVELOPMENT for…”
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Correction: Transforming Drug Development for Neurological Disorders: Proceedings from a Multidisease Area Workshop
Published in Neurotherapeutics (01-10-2023)Get full text
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Transforming Drug Development for Neurological Disorders: Proceedings from a Multidisease Area Workshop
Published in Neurotherapeutics (01-10-2023)“…Neurological disorders represent some of the most challenging therapeutic areas for successful drug approvals. The escalating global burden of death and…”
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The Critical Path for Alzheimer’s Disease (CPAD) Consortium: A platform for pre‐competitive data sharing, standardization, and analysis to support quantitative tools for AD drug development
Published in Alzheimer's & dementia (01-12-2021)“…Background The primary objective of the Critical Path for Alzheimer’s Disease (CPAD) consortium, a pre‐competitive consortium of the Critical Path Institute,…”
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Harmonization of tau‐PET in Alzheimer’s disease: comparison of methods to derive CenTauR units for [18F]RO948, [18F]Flortaucipir, and [18F]MK‐6240
Published in Alzheimer's & dementia (01-12-2023)“…Background Tau positron emission tomography (PET) is increasingly used in the clinical evaluation of patients and as an outcome measure in Alzheimer’s disease…”
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Harmonization of tau‐PET in Alzheimer’s disease: comparison of methods to derive CenTauR units for [18F]RO948, [18F]Flortaucipir, and [18F]MK‐6240
Published in Alzheimer's & dementia (01-12-2023)“…Background Tau positron emission tomography (PET) is increasingly used in the clinical evaluation of patients and as an outcome measure in Alzheimer’s disease…”
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Visual half-field contrast sensitivity in children with dyslexia
Published in Documenta ophthalmologica (1998)“…We address the question whether left-hemispheric and/or right-hemispheric contrast thresholds differ between children with dyslexia and controls, and whether…”
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