Search Results - "Kartalia, Emma"

Abstract 6819: Exploring the impact of IDH1- mutations on antitumor immunity in intrahepatic cholangiocarcinoma by Kartalia, Emma, Leatherman, James M., Lee, Jae W., Yoshima, Kiyoko, Zabransky, Daniel J., Yarchoan, Mark

“…Intrahepatic cholangiocarcinoma (CCA) is an aggressive biliary tract cancer that carries unfavorable prognosis. 10-20% of intrahepatic CCAs harbor a mutation…”
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Fibroblasts in the Aged Pancreas Drive Pancreatic Cancer Progression by Zabransky, Daniel J, Chhabra, Yash, Fane, Mitchell E, Kartalia, Emma, Leatherman, James M, Hüser, Laura, Zimmerman, Jacquelyn W, Delitto, Daniel, Han, Song, Armstrong, Todd D, Charmsaz, Soren, Guinn, Samantha, Pramod, Sneha, Thompson, Elizabeth D, Hughes, Steven J, O'Connell, Jennifer, Egan, Josephine M, Jaffee, Elizabeth M, Weeraratna, Ashani T

“…Pancreatic cancer is more prevalent in older individuals and often carries a poorer prognosis for them. The relationship between the microenvironment and…”
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Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma by Shu, Daniel H., Ho, Won Jin, Kagohara, Luciane T., Girgis, Alexander, Shin, Sarah M., Danilova, Ludmila, Lee, Jae W., Sidiropoulos, Dimitrios N., Mitchell, Sarah, Munjal, Kabeer, Howe, Kathryn, Bendinelli, Kayla J., Kartalia, Emma, Qi, Hanfei, Mo, Guanglan, Montagne, Janelle, Leatherman, James M., Lopez-Vidal, Tamara Y., Zhu, Qingfeng, Huff, Amanda L., Yuan, Xuan, Hernandez, Alexei, Coyne, Erin M., Zaidi, Neeha, Zabransky, Daniel J., Engle, Logan L., Ogurtsova, Aleksandra, Baretti, Marina, Laheru, Daniel, Durham, Jennifer N., Wang, Hao, Sunshine, Joel C., Johnston, Robert J., Deutsch, Julie Stein, Taube, Janis M., Anders, Robert A., Jaffee, Elizabeth M., Fertig, Elana J., Yarchoan, Mark

“…Tertiary lymphoid structures (TLS) are associated with improved response in solid tumors treated with immune checkpoint blockade, but understanding of the…”
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Abstract 6631: Aging influences the pancreatic ductal adenocarcinoma tumor immune microenvironment to promote features of immunosuppression by Kartalia, Emma, Leatherman, James M., Lee, Jae W., Jaffee, Elizabeth M., Weeraratna, Ashani T., Zabransky, Daniel J.

“…Advancing age is the strongest independent risk factor for the development of pancreatic ductal adenocarcinoma (PDAC) and a negative prognostic factor. PDACs…”
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Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial-Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma by Guinn, Samantha, Kinny-Köster, Benedict, Tandurella, Joseph A, Mitchell, Jacob T, Sidiropoulos, Dimitrios N, Loth, Melanie, Lyman, Melissa R, Pucsek, Alexandra B, Zabransky, Daniel J, Lee, Jae W, Kartalia, Emma, Ramani, Mili, Seppälä, Toni T, Cherry, Christopher, Suri, Reecha, Zlomke, Haley, Patel, Jignasha, He, Jin, Wolfgang, Christopher L, Yu, Jun, Zheng, Lei, Ryan, David P, Ting, David T, Kimmelman, Alec, Gupta, Anuj, Danilova, Ludmila, Elisseeff, Jennifer H, Wood, Laura D, Stein-O'Brien, Genevieve, Kagohara, Luciane T, Jaffee, Elizabeth M, Burkhart, Richard A, Fertig, Elana J, Zimmerman, Jacquelyn W

“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy characterized by an immunosuppressive tumor microenvironment enriched with…”
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Abstract 1337: Aged pancreatic fibroblasts enhance pancreatic cancer growth and progression by Zabransky, Daniel J., Chhabra, Yash, Fane, Mitchell, Kartalia, Emma, Leatherman, James, Zimmerman, Jacquelyn, Jaffee, Elizabeth, Weeraratna, Ashani

“…Advancing age is a major independent risk factor for the development of pancreatic ductal adenocarcinoma (PDAC). However, the ways in which aging alters cells…”
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Abstract 1577: Cancer associated fibroblast - tumor cell crosstalk enhances epithelial to mesenchymal transition and promotes a classical to basal switch in human pancreatic ductal adenocarcinoma by Guinn, Samantha, Perez, Brayan, Patel, Jignasha, Lee, Jae, Zabransky, Daniel, Ho, Won, Fertig, Elana J., Kartalia, Emma, Tandurella, Joseph, Burkhart, Richard, Zimmerman, Jacquelyn W., Jaffee, Elizabeth

“…Introduction: Cancer associated fibroblasts (CAF) drive a complex tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) through incompletely…”
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Abstract B071: Antigen-presenting cancer-associated fibroblasts are required for ICI-sensitivity in pancreatic ductal adenocarcinoma by Maru, Saumya, Wetzel, Meredith, Mitchell, Jacob T, Gross, Nicole, Andaloori, Lalitya, Howe, Kathryn, Kartalia, Emma, Mo, Guanglan, Leatherman, James, Ho, Won Jin, Kagohara, Luciane, Fertig, Elana, Pearce, Edward J, Jaffee, Elizabeth M

“…Cancer-associated fibroblasts (CAFs) are a hallmark of many cancers and are particularly prevalent in pancreatic ductal adenocarcinoma (PDAC). This highly…”
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Abstract A032: Cancer associated fibroblasts drive classical to basal change associated with increased T cell presence in pancreatic ductal adenocarcinoma by Zimmerman, Jacquelyn W, Guinn, Samantha, Ramani, Mili, Perez, Brayan, Tandurella, Joseph A, Zabransky, Daniel J, Lee, Jae W, Kartalia, Emma, Patel, Jignasha, Shin, Sarah, Hernandez, Alexei, Cannon, Courtney, Gross, Nicole, Charmsaz, Soren, Fertig, Elana J, Burkhart, Richard A, Ho, Won J, Jaffee, Elizabeth M

“…Introduction: A complex immunosuppressive tumor microenvironment (TME) is a distinctive feature of pancreatic ductal adenocarcinoma (PDAC). The TME consists of…”
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Abstract 3679: DNAJB1-PRKACA fusion in fibrolamellar hepatocellular carcinoma induces glutamine addiction and an immunosuppressive tumor microenvironment by Kamdar, Zeal, Lopez-Vidal, Tamara, Howe, Kathryn, Munjal, Kabeer, Saeed, Ali, Zabransky, Daniel, Shu, Daniel, Longway, Gabriella, Kartalia, Emma, Leatherman, James, Mohan, Aditya, Khare, Pratik, Zhang, Cissy, Le, Anne, Pearce, Erika, Furth, Mark, Baretti, Marina, Leone, Robert, Jaffee, Elizabeth, Yarchoan, Mark

“…Fibrolamellar hepatocellular carcinoma (FLC) is a rare and often lethal form of liver cancer that primarily affects children and young adults. A fusion between…”
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