Search Results - "Kartal Yandım, Melis"

Therapeutic potential of targeting ceramide/glucosylceramide pathway in cancer by Kartal Yandım, Melis, Apohan, Elif, Baran, Yusuf

“…Sphingolipids including ceramides and its derivatives such as ceramide-1-phosphate, glucosylceramide (GlcCer), and sphingosine-1-phosphate are essential…”
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Major apoptotic mechanisms and genes involved in apoptosis by Kiraz, Yağmur, Adan, Aysun, Kartal Yandim, Melis, Baran, Yusuf

“…As much as the cellular viability is important for the living organisms, the elimination of unnecessary or damaged cells has the opposite necessity for the…”
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Effects of Intraperitoneal Injection of Allogeneic Bone Marrow-derived Mesenchymal Stem Cells on Bronchiolitis Obliterans in Mice Model by Işık, Sakine, Uzuner, Nevin, Karaman, Meral, Karaman, Özkan, Kıray, Müge, Kozanoğlu, İlknur, Alper Bağrıyanık, Hüsnü, Arıkan-Ayyıldız, Zeynep, Kartal Yandım, Melis, Baran, Yusuf

“…Bone marrow-derived mesenchymal stem cells (BMSCs) can ameliorate a variety of lung diseases such as asthma, lung fibrosis, and acute lung injury by its…”
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Molecular mechanisms of drug resistance and its reversal in cancer by Kartal-Yandim, Melis, Adan-Gokbulut, Aysun, Baran, Yusuf

“…Chemotherapy is the main strategy for the treatment of cancer. However, the main problem limiting the success of chemotherapy is the development of multidrug…”
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Revealing genome-wide mRNA and microRNA expression patterns in leukemic cells highlighted “hsa-miR-2278” as a tumor suppressor for regain of chemotherapeutic imatinib response due to targeting STAT5A by Kaymaz, Burçin Tezcanlı, Günel, Nur Selvi, Ceyhan, Metin, Çetintaş, Vildan Bozok, Özel, Buket, Yandım, Melis Kartal, Kıpçak, Sezgi, Aktan, Çağdaş, Gökbulut, Aysun Adan, Baran, Yusuf, Can, Buket Kosova

“…BCR-ABL oncoprotein stimulates cell proliferation and inhibits apoptosis in chronic myeloid leukemia (CML). For cure, imatinib is a widely used tyrosine kinase…”
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PB1793: MCL‐1 INHIBITION AFFECTS LIPIDOME WHICH MAY BE LINKED TO TUMOR IMMUNITY AND CANCER‐RELATED INFLAMMATION IN ACUTE MYELOID LEUKEMIA by Yandim, Melis Kartal, Bilgin, Mesut

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New indication for therapeutic potential of an old well-known drug (propranolol) for multiple myeloma by Kozanoglu, Ilknur, Yandim, Melis Kartal, Cincin, Zeynep Birsu, Ozdogu, Hakan, Cakmakoglu, Bedia, Baran, Yusuf

“…Purpose Propranolol, a non-selective β-adrenergic receptor blocker, has been used for the treatment of the patients with hypertension for more than 50 years…”
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Targeting FOXM1 Transcription Factor In T-Cell Acute Lymphoblastic Leukemia by Tüfekçi, Özlem, Yandım, Melis Kartal, Ören, Hale, Irken, Gülersu, Baran, Yusuf

“…The Forkhead box protein M1(FoxM1) is an important  transcriptional factor that takes play in regulation of cell cyle, proliferation, DNA repair, apoptosis,…”
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Targeting FoxM1 transcription factor in T-cell acute lymphoblastic leukemia cell line by Tüfekçi, Özlem, Yandım, Melis Kartal, Ören, Hale, İrken, Gülersu, Baran, Yusuf

“…Highlights • FoxM1 mRNA is highly expressed in T-cell acute lymphoblastic leukemia cell line (Jurkat cells). • Targeting FoxM1 by siomycin A and dexamethasone…”
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PP-018 APPLYING TEAM-BASED LEARNING FOR THE INTEGRATION OF BASIC MEDICAL DISCIPLINES ON TOPC “THE CELL:” A PILOT EVALUATION by Akdoğan, Gül Güner, Kartal, Melis Yandım, Çelik, Yasemin Seval, Demir, Banu, Özkaya, Ali Burak, İnan, Sevinç, Abacıoğlu, Hakan

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Expression Levels of Bioactive Sphingolipid Genes in Newly Diagnosed and Drug-Resistant Chronic Myeloid Leukemia Patients and Their Impact on the Clinical Progress by Kartal Yandım, Melis

“…Bioactive sphingolipids are a family of lipids including ceramide, glucosylceramide (GC), sphingosine-1-phosphate (S1P) and ceramide-1-phosphate (C1P) that…”
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A molecular and biophysical comparison of macromolecular changes in imatinib-sensitive and imatinib-resistant K562 cells exposed to ponatinib by Yandim, Melis Kartal, Ceylan, Cagatay, Elmas, Efe, Baran, Yusuf

“…Chronic myeloid leukemia (CML) is a type of hematological malignancy that is characterized by the generation of Philadelphia chromosome encoding BCR/ABL…”
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Effects of cell-mediated osteoprotegerin gene transfer and mesenchymal stem cell applications on orthodontically induced root resorption of rat teeth by Amuk, Nisa Gul, Kurt, Gökmen, Baran, Yusuf, Seyrantepe, Volkan, Yandim, Melis Kartal, Adan, Aysun, Demir, Secil Akyildiz, Kiraz, Yagmur, Sonmez, Mehmet Fatih

“…The aim of this study is to evaluate and compare therapeutic effects of mesenchymal stem cell (MSCs) and osteoprotegerin (OPG) gene transfer applications on…”
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A minimally invasive transfer method of mesenchymal stem cells to the intact periodontal ligament of rat teeth: a preliminary study by Gül Amuk, Nisa, Kurt, Gökmen, Kartal Yandim, Melis, Adan, Aysun, Baran, Yusuf

“…The aim of this study was to introduce a minimally invasive procedure for mesenchymal stem cell (MSC) transfer into the intact periodontal ligament (PDL) of…”
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STAT pathway in the regulation of zoledronic acid-induced apoptosis in chronic myeloid leukemia cells by Kiper, Hatice Demet, Tezcanli Kaymaz, Burcin, Gokbulut, Aysun Adan, Selvi, Nur, Avci, Cigir Biray, Kosova, Buket, Iskender, Guniz, Yandim, Melis Kartal, Gunduz, Cumhur, Sahin, Fahri, Baran, Yusuf, Saydam, Guray

“…Abstract In this study, we aimed to evaluate the cytotoxic and apoptotic effects of zoledronic acid on K562 chronic myeloid leukemia (CML) cells and to examine…”
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