Search Results - "Karson, Craig N."

Evaluation of Functionally Meaningful Measures for Clinical Trials of Cognition Enhancement in Schizophrenia by Green, Michael F., Schooler, Nina R., Kern, Robert S., Frese, Fred J., Granberry, Wendy, Harvey, Philip D., Karson, Craig N., Peters, Nancy, Stewart, Michelle, Seidman, Larry J., Sonnenberg, John, Stone, William S., Walling, David, Stover, Ellen, Marder, Stephen R.

“…Objective:Because reduction of psychotic symptoms in schizophrenia does not result in adequate community functioning, efforts have shifted to other areas, such…”
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Phospholipid abnormalities in postmortem schizophrenic brains detected by 31P nuclear magnetic resonance spectroscopy: a preliminary study by Komoroski, Richard A., Pearce, John M., Griffin, W.Sue T., Mrak, Robert E., Omori, Masao, Karson, Craig N.

“…It has been hypothesized that schizophrenia arises from cell membrane abnormalities due to changes in phospholipid (PL) composition and metabolism. We have…”
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In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of subjects with combat-related posttraumatic stress disorder by Freeman, T W, Cardwell, D, Karson, C N, Komoroski, R A

“…Recent findings using volumetric MRI techniques have revealed that patients with combat-related and noncombat-related posttraumatic stress disorder (PTSD) have…”
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Mitogen-activated protein kinases in schizophrenia by Kyosseva, Svetlana V, Elbein, Alan D, Griffin, W.Sue T, Mrak, Robert E, Lyon, Melvin, Karson, Craig N

“…Background: Mitogen-activated protein kinases (MAPKs) are important mediators of signal transduction from the cell surface to the nucleus and have been…”
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Regional proton magnetic resonance spectroscopy in schizophrenia and exploration of drug effect by Heimberg, Carolyn, Komoroski, Richard A, Lawson, William B, Cardwell, David, Karson, Craig N

“…Schizophrenia is a disorder with an unclear pathophysiology, despite numerous attempts to elucidate its etiology. We have employed proton magnetic resonance…”
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Differential and Region-Specific Activation of Mitogen-Activated Protein Kinases Following Chronic Administration of Phencyclidine in Rat Brain by Kyosseva, Svetlana V, Owens, S.Michael, Elbein, Alan D, Karson, Craig N

“…We have previously demonstrated elevation of the extracellular signal-regulated kinase (ERK) pathway in the cerebellum from patients with schizophrenia, an…”
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Effects of gender and region on proton MRS of normal human brain by Komoroski, Richard A, Heimberg, Carolyn, Cardwell, David, Karson, Craig N

“…Localized, in vivo 1H magnetic resonance spectroscopy has been performed in a number of brain regions of neuropsychiatric interest in male and female control…”
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Choline acetyltransferase in schizophrenia by Karson, C N, Casanova, M F, Kleinman, J E, Griffin, W S

“…To test the hypothesis that schizophrenia involves altered cholinergic tone in the pons, the authors studied post-mortem brain tissue from subjects with…”
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Combat veterans with posttraumatic stress disorder exhibit decreased habituation of the P1 midlatency auditory evoked potential by Gillette, Gregory M., Skinner, Robert D., Rasco, Lisa M., Fielstein, Elliot M., Davis, Doyle H., Pawelak, James E., Freeman, Thomas W., Karson, Craig N., Boop, Frederick A., Garcia-Rill, Edgar

“…The current study used a paired stimulus paradigm to investigate the P1 midlatency auditory evoked potential in Vietnam combat veterans with posttraumatic…”
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Correlation of severity of psychiatric patients' delusions with right hemispatial inattention (left-turning behavior) by Bracha, H S, Livingston, R L, Clothier, J, Linington, B B, Karson, C N

“…Studies associate psychotic disorders with various forms of subtle inattention to the right hemispace (left-turning behavior). The authors examined the…”
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Blink Rates in Schizophrenia by Karson, Craig N., Dykman, Roscoe A., Paige, Stephen R.

“…In schizophrenia, blink rates are frequently elevated and the peak of the electroencephalographic alpha rhythm is often absent or of a lower frequency…”
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Dyskinetic movements, cognitive impairment, and negative symptoms in elderly neuropsychiatric patients by Karson, C N, Bracha, H S, Powell, A, Adams, L

“…The presence or absence of tardive dyskinesia, cognitive status, and psychopathology were assessed in a group of elderly male psychiatric patients (N = 49) in…”
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Computerized EEG in Schizophrenia by Karson, Craig N., Coppola, Richard, Daniel, David G., Weinberger, Daniel R.

“…Despite advances in the processing and display of electroencephalographic (EEG) data, the utility of this inexpensive and noninvasive technique in the…”
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Assault increases the cost of care among inpatient veterans with schizophrenia by Karson, C N, Kashner, T M

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Blink rates in parkinsonism by Karson, C N, LeWitt, P A, Calne, D B, Wyatt, R J

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Eye-blink rate in Tourette's syndrome by Karson, C N, Kaufmann, C A, Shapiro, A K, Shapiro, E

“…Gilles de la Tourette's syndrome is a hyperkinetic movement disorder in which an etiological role for dopaminergic hyperactivity has been proposed. Blink rate,…”
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Increased Levels of Transcription Factors Elk-1, Cyclic Adenosine Monophosphate Response Element-Binding Protein, and Activating Transcription Factor 2 in the Cerebellar Vermis of Schizophrenic Patients by Kyosseva, Svetlana V, Elbein, Alan D, Hutton, Theron L, Griffin, W. Sue T, Mrak, Robert E, Sturner, William Q, Karson, Craig N

“…BACKGROUND We investigated the levels of transcription factors associated with activation of the mitogen-activated protein (MAP) kinase pathway in…”
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Reduced sensory gating of the P1 potential in rape victims and combat veterans with posttraumatic stress disorder by Skinner, R.D., Rasco, L.M., Fitzgerald, J., Karson, C.N., Matthew, M., Williams, D.K., Garcia-Rill, E.

“…The P1 midlatency auditory evoked potential was studied in female rape victims with Posttraumatic Stress Disorder (PTSD) and compared to an age‐matched female…”
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Effects of antipsychotic drugs on metabolite ratios in rat brain in vivo by Lindquist, Diana M., Hawk, Roger M., Karson, Craig N., Komoroski, Richard A.

“…Localized in vivo proton magnetic resonance spectroscopy at 4.7 T was used to examine the brains of rats that were given the antipsychotic drugs haloperidol,…”
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Spontaneous eye-blink rates and dopaminergic systems by Karson, C N

“…A series of studies demonstrated a possible relationship between eye-blink rate and central dopamine activity. First, apomorphine and other dopamine agonists…”
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