Search Results - "Karschin, Christine"

Molecular and Cellular Diversity of Neuronal G-Protein-Gated Potassium Channels by Koyrakh, Lev, Lujan, Rafael, Colon, Jose, Karschin, Christine, Kurachi, Yoshihisa, Karschin, Andreas, Wickman, Kevin

“…Neuronal G-protein-gated potassium (GIRK) channels mediate the inhibitory effects of many neurotransmitters. Although the overlapping distribution of GIRK…”
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IRK(1-3) and GIRK(1-4) Inwardly Rectifying K+ Channel mRNAs Are Differentially Expressed in the Adult Rat Brain by Karschin, Christine, Dissmann, Elke, Stuhmer, Walter, Karschin, Andreas

“…Molecular cloning together with functional characterization has shown that the newly identified family of inwardly rectifying K+ channels consists of several…”
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THIK-1 and THIK-2, a Novel Subfamily of Tandem Pore Domain K+ Channels by Rajan, S, Wischmeyer, E, Karschin, C, Preisig-Müller, R, Grzeschik, K H, Daut, J, Karschin, A, Derst, C

“…Two cDNAs encoding novel K + channels, THIK-1 and THIK-2 ( t andem pore domain h alothane i nhibited K + channel), were isolated from rat brain. The proteins…”
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Brain Localization and Behavioral Impact of the G-Protein-Gated K+ Channel Subunit GIRK4 by Wickman, Kevin, Karschin, Christine, Karschin, Andreas, Picciotto, Marina R, Clapham, David E

“…Neuronal G-protein-gated potassium (K(G)) channels are activated by several neurotransmitters and constitute an important mode of synaptic inhibition in the…”
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Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2 by Gu, Wenli, Schlichthörl, Günter, Hirsch, Jochen R., Engels, Hartmut, Karschin, Christine, Karschin, Andreas, Derst, Christian, Steinlein, Ortrud K., Daut, Jürgen

“…Two novel alternatively spliced isoforms of the human two-pore-domain potassium channel TREK-2 were isolated from cDNA libraries of human kidney and fetal…”
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Ontogeny of Gene Expression of Kir Channel Subunits in the Rat by Karschin, Christine, Karschin, Andreas

“…We report the detailed gene expression of all subunits within the Kir2 and Kir3 inwardly rectifying K+channel subfamilies in the developing rat. Usingin…”
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Genetic and functional linkage of Kir5.1 and Kir2.1 channel subunits by Derst, Christian, Karschin, Christine, Wischmeyer, Erhard, Hirsch, Jochen R., Preisig-Müller, Regina, Rajan, Sindhu, Engel, Hartmut, Grzeschik, Karl-Heinz, Daut, Jürgen, Karschin, Andreas

“…We have identified several cDNAs for the human Kir5.1 subunit of inwardly rectifying K + channels. Alternative splicing of exon 3 and the usage of two…”
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Cloning and Tissue Distribution of a Novel P2X Receptor from Rat Brain by Soto, Florentina, Garcia-Guzman, Miguel, Karschin, Christine, Stühmer, Walter

“…We have isolated the cDNA for a novel member (P2X6) of the ATP-gated ion channel family. The rat P2X6nucleotide sequence encodes a 379 amino acid protein that…”
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Overlapping distribution of KATP channel‐forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain by Karschin, Christine, Ecke, Claudia, Ashcroft, Frances M, Karschin, Andreas

“…ATP‐sensitive K+ channels comprise a complex of at least two proteins: a member of the inwardly rectifying Kir6 family (e.g. Kir6.2) and a sulphonylurea…”
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Overlapping distribution of K ATP channel-forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain by Karschin, Christine, Ecke, Claudia, Ashcroft, Frances M, Karschin, Andreas

“…ATP-sensitive K + channels comprise a complex of at least two proteins: a member of the inwardly rectifying Kir6 family (e.g. Kir6.2) and a sulphonylurea…”
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Overlapping distribution of K(ATP) channel-forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain by Karschin, C, Ecke, C, Ashcroft, F M, Karschin, A

“…ATP-sensitive K+ channels comprise a complex of at least two proteins: a member of the inwardly rectifying Kir6 family (e.g. Kir6.2) and a sulphonylurea…”
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GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex by Minelli, A, Brecha, NC, Karschin, C, DeBiasi, S, Conti, F

“…High affinity, GABA plasma membrane transporters influence the action of GABA, the main inhibitory neurotransmitter. The cellular expression of GAT-1, a…”
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P2X4: An ATP-Activated Ionotropic Receptor Cloned from Rat Brain by Soto, Florentina, Garcia-Guzman, Miguel, Gomez-Hernandez, Juan Manuel, Hollmann, Michael, Karschin, Christine, Stühmer, Walter

“…Extracellular ATP exerts pronounced biological actions in virtually every organ or tissue that has been studied. In the central and peripheral nervous system,…”
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Expression Pattern in Brain of TASK-1, TASK-3, and a Tandem Pore Domain K+ Channel Subunit, TASK-5, Associated with the Central Auditory Nervous System by Karschin, Christine, Wischmeyer, Erhard, Preisig-Müller, Regina, Rajan, Sindhu, Derst, Christian, Grzeschik, Karl-Heinz, Daut, Jürgen, Karschin, Andreas

“…TWIK-related acid-sensitive K+ (TASK) channels contribute to setting the resting potential of mammalian neurons and have recently been defined as molecular…”
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Kir6.1 Is the Principal Pore-Forming Subunit of Astrocyte but Not Neuronal Plasma Membrane K-ATP Channels by Thomzig, Achim, Wenzel, Mareike, Karschin, Christine, Eaton, Misty J., Skatchkov, Serguei N., Karschin, Andreas, Veh, Rüdiger W.

“…ATP-sensitive potassium channels (K-ATP channels) directly couple the energy state of a cell to its excitability, are activated by hypoxia, and have been…”
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The Epithelial Inward Rectifier Channel Kir7.1 Displays Unusual K+ Permeation Properties by Doring, Frank, Derst, Christian, Wischmeyer, Erhard, Karschin, Christine, Schneggenburger, Ralf, Daut, Jurgen, Karschin, Andreas

“…Rat and human cDNAs were isolated that both encoded a 360 amino acid polypeptide with a tertiary structure typical of inwardly rectifying K+ channel (Kir)…”
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Kir2.4: A Novel K+ Inward Rectifier Channel Associated with Motoneurons of Cranial Nerve Nuclei by Topert, Christoph, Doring, Frank, Wischmeyer, Erhard, Karschin, Christine, Brockhaus, Johannes, Ballanyi, Klaus, Derst, Christian, Karschin, Andreas

“…Members of the Kir2 subfamily of inwardly rectifying K+ channels characterized by their strong current rectification are widely expressed both in the periphery…”
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A G-protein-activated inwardly rectifying K+ channel (GIRK4) from human hippocampus associates with other GIRK channels by Spauschus, A, Lentes, KU, Wischmeyer, E, Dissmann, E, Karschin, C, Karschin, A

“…Transcripts of a gene, GIRK4, that encodes for a 419-amino-acid protein and shows high structural similarity to other subfamily members of G-protein-activated…”
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Distribution and localization of a G protein-coupled inwardly rectifying K + channel in the rat by Karschin, Christine, Schreibmayer, Wolfgang, Dascal, Nathan, Lester, Henry, Davidson, Norman, Karschin, Andreas

“…The cellular distribution of the mRNA of the inwardly rectifying K + channel KGA (GIRK1) was investigated in rat tissue by in situ hybridization. KGA was…”
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THIK-1 and THIK-2, a Novel Subfamily of Tandem Pore Domain K+ Channels210 by Rajan, Sindhu, Wischmeyer, Erhard, Karschin, Christine, Preisig-Müller, Regina, Grzeschik, Karl-Heinz, Daut, Jürgen, Karschin, Andreas, Derst, Christian

“…Two cDNAs encoding novel K+channels, THIK-1 and THIK-2 (tandem pore domainhalothane inhibited K+channel), were isolated from rat brain. The proteins of 405 and…”
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