Search Results - "Kars, Meltem Demirel"

Biocompatible yogurt carbon dots: evaluation of utilization for medical applications by Dinç, Saliha, Kara, Meryem, Demirel Kars, Meltem, Aykül, Fatmanur, Çiçekci, Hacer, Akkuş, Mehmet

“…In this study, carbon dots (CDs) were produced from yogurt, a fermented milk product, via microwave-assisted process (800 W) in 30 min without using any…”
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Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells by Dönmez, Yaprak, Akhmetova, Laila, İşeri, Özlem Darcansoy, Kars, Meltem Demirel, Gündüz, Ufuk

“…Purpose One of the major problems of cancer chemotherapy is the development of multidrug resistance (MDR) phenotype. Among the numerous mechanisms of MDR, a…”
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Anticancer effects of the organosilicon multidrug resistance modulator SILA 421 by Olszewski, Ulrike, Zeillinger, Robert, Kars, Meltem Demirel, Zalatnai, Attila, Molnar, Jozsef, Hamilton, Gerhard

“…1,3-dimethyl-1,3-bis(4-fluorophenyl)-1,3-bis{3-[1(4-butylpiperazinyl)]-propyl}-disiloxan-tetrahydrochlorid (SILA 421) is a compound that was developed as…”
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Exploring a natural MDR reversal agent: potential of medicinal food supplement Nerium oleander leaf distillate by Meltem Demirel Kars Ufuk Gündüz Kamilüney AhmetLevent Ba

“…Objective:To investigate the molecular effects ofNerium oleanderleaf distillate on paclitaxel and vincristine resistant(MCF-7/Pac and MCF-7/Vinc)cells and…”
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Cytotoxic and Genotoxic Assessment of Silicon Dioxide Nanoparticles by Allium and Comet Tests by Liman, Recep, Acikbas, Yaser, Ciğerci, İbrahim Hakkı, Ali, Muhammad Muddassir, Kars, Meltem Demirel

“…Silicon nanoparticles gained a great interest due to its use in biomedical research. It is considered as safe and has been used in nanomedicine. But literature…”
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In vitro assessment of Momordica charantia / Hypericum perforatum oils loaded PCL/Collagen fibers: Novel scaffold for tissue engineering by Ediz, Emre Fatih, Güneş, Cansu, Demirel Kars, Meltem, Avcı, Ahmet

“…The research on tissue engineering applications has been progressing to manufacture ideal tissue scaffold biomaterials. In this study, a double-layered…”
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Enhancement of PCL/PLA Electrospun Nanocomposite Fibers Comprising Silver Nanoparticles Encapsulated with Thymus Vulgaris L. Molecules for Antibacterial and Anticancer Activities by Güneş Çimen, Cansu, Dündar, Mehmet Akif, Demirel Kars, Meltem, Avcı, Ahmet

“…Silver nanoparticles (AgNPs) have been recognized for their outstanding antibacterial activities, which are required for antibacterial coating materials in…”
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Biocompatible multi-walled carbon nanotube–CdTe quantum dot–polymer hybrids for medical applications by Baslak, Canan, Demirel Kars, Meltem, Karaman, Mustafa, Kus, Mahmut, Cengeloglu, Yunus, Ersoz, Mustafa

“…Herein we report the synthesis of polymer coated quantum dots (QDs)–carbon nanotube composite material with high biocompatibility and low cellular toxicity…”
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Response to trastuzumab and investigation of expression profiles of matrix metalloproteinase-related proteins in primary breast cancer stem cells by Koygun, Gozde Kayadibi, Kars, Meltem Demirel, Emsen, Ayca, Artac, Hasibe, Aksoy, Faruk, Cakir, Murat, Tavli, Lema, Artac, Mehmet

“…Breast cancer (BC) is the leading cause of cancer deaths in women. One of the reasons for the failure of BC treatment is reportedly the ineffectiveness of…”
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Gene expression analysis of drug-resistant MCF-7 cells: implications for relation to extracellular matrix proteins by Işeri, Özlem Darcansoy, Kars, Meltem Demirel, Arpaci, Fikret, Gündüz, Ufuk

“…Purpose Since multidrug resistance is a multifactorial phenomenon, a large-scale expression analysis of drug-resistant cells by using high-density…”
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Revealing the therapeutic effects of aminolevulinate mediated femtosecond laser induced photo-chemotherapy in different cancer cells by Kars, Meltem Demirel, Yıldırım, Gamze, Gündoğdu, Yasemin, Gönce, Fatmanur, Ayan, Esra, Kılıç, Hamdi Şükür

“…Photodynamic therapy (PDT) is a photo chemotherapeutic strategy that is the application of photosensitizing agent and light on disease or tumor site. The aim…”
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Implications from a pharmacogenomic analysis: Nerium oleander leaf distillate supplemented diet regulates cholesterol metabolism in rats by Demirel Kars, Meltem, Odabaşı, Burcu Asena, Kars, Gökhan, Üney, Kamil, Bağcı, Yavuz, Baş, Ahmet Levent

“…Despite the usage of Nerium oleander L. (Apocynaceae) for anticancer studies and traditional remediation, the regulatory effect of N. oleander leaf distillate…”
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In Vitro Evaluation of Zoledronic Acid Resistance Developed in MCF-7 Cells by KARS, Meltem Demirel, ISERI, Özlem Darcansoy, URAL, Ali Ugur, GÜNDÜZ, Ufuk

“…Background: Zoledronic acid is an important osteotropic compound used in combination with anticancer agents to reduce the incidence of hypercalcemia and…”
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Determination of the target proteins in chemotherapy resistant breast cancer stem cell-like cells by protein array by Kars, Meltem Demirel, Yıldırım, Gamze

“…Breast cancer comes second among the causes of cancer deaths of women. Although new generation hormone therapy is a promising strategy, re-occurrence or…”
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Investigating the Effects of DNA Demethylation in Chemotherapy Resistance by ChIP-on-Chip Method by Meltem Demi̇rel Kars, Koygun, Gözde

“…OBJECTIVE This study aimed to determine the epigenetic basis of drug resistance mechanisms developed in MCF-7 breast cancer cell line that is resistant to an…”
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In vitro assessment of / oils loaded PCL/Collagen fibers: Novel scaffold for tissue engineering by Emre Fatih Ediz, Cansu Güneş, Meltem Demirel Kars, Ahmet Avcı

“…The research on tissue engineering applications has been progressing to manufacture ideal tissue scaffold biomaterials. In this study, a double-layered…”
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Meme kanseri MCF-7 hücre hattında paklitaksel ve vinkristin'e karşı gelişmiş çoklu ilaç direnci mekanizmalarının mikrodizin analizi ile belirlenmesi by KARS, Meltem, Demirel, İŞERİ, Özlem, Darcansoy, GÜNDÜZ, Ufuk, ARPACI, Fikret

“…AMAÇ Sonradan kazanılan veya tedavi öncesi varolan çoklu ilaç dirençliliği (ÇİD) kemoterapide başarıyı engelleyen nedenlerden biridir. Bu çalışmada,…”
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Drug resistance restricts the efficacy of short term low dose Mitomycin-C treatment in UMUC-3 bladder cancer cells by Gul, Murat, Goktas, Serdar, Kars, Meltem Demirel, Kaynar, Mehmet

“…Mitomycin-c (MMC) is the most used intravesical adjuvant agent in non-muscle invasive bladder cancer to prevent recurrence. However, a consensus on about…”
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Fomes fomentarius and Tricholoma anatolicum (Agaricomycetes) Extracts Exhibit Significant Multiple Drug-Resistant Modulation Activity in Drug-Resistant Breast Cancer Cells by Doğan, Hasan Hüseyin, Kars, Meltem Demirel, Özdemir, Özdem, Gündüz, Ufuk

“…Multiple drug resistance is one of the main problems that hinder successful cancer chemotherapy. Investigations on the development of effective…”
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Biomarkers to target and silence stemness of breast cancer stem cell model: silencing MDR1 by siRNA by Yıldırım, Gamze, Kars, Meltem D., Kars, Gökhan, Kılıç, Hamdi Ş.

“…Abstract Objectives Aim of the study was to reveal new biomarker genes to target breast cancer stem-like cells (BCSC-like) and then sensitize BCSC-like cells…”
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