Search Results - "Karrich, Julien J."

The Transcription Factor GATA3 Is Essential for the Function of Human Type 2 Innate Lymphoid Cells by Mjösberg, Jenny, Bernink, Jochem, Golebski, Korneliusz, Karrich, Julien J., Peters, Charlotte P., Blom, Bianca, te Velde, Anje A., Fokkens, Wytske J., van Drunen, Cornelis M., Spits, Hergen

“…Type 2 innate lymphoid cells (ILC2s) are part of a large family of ILCs that are important effectors in innate immunity, lymphoid organogenesis, and tissue…”
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Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage by Aparicio-Domingo, Patricia, Romera-Hernandez, Monica, Karrich, Julien J, Cornelissen, Ferry, Papazian, Natalie, Lindenbergh-Kortleve, Dicky J, Butler, James A, Boon, Louis, Coles, Mark C, Samsom, Janneke N, Cupedo, Tom

“…Disruption of the intestinal epithelial barrier allows bacterial translocation and predisposes to destructive inflammation. To ensure proper barrier…”
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Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells by Romera-Hernández, Mónica, Aparicio-Domingo, Patricia, Papazian, Natalie, Karrich, Julien J., Cornelissen, Ferry, Hoogenboezem, Remco M., Samsom, Janneke N., Cupedo, Tom

“…Tissue repair requires temporal control of progenitor cell proliferation and differentiation to replenish damaged cells. In response to acute insult, group 3…”
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The plasmacytoid dendritic cell as the Swiss army knife of the immune system: molecular regulation of its multifaceted functions by Karrich, Julien J, Jachimowski, Loes C M, Uittenbogaart, Christel H, Blom, Bianca

“…Plasmacytoid dendritic cells (pDC) have been regarded as the "professional type I IFN-producing cells" of the immune system following viral recognition that…”
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Humanized MISTRG as a preclinical in vivo model to study human neutrophil-mediated immune processes by Martinez-Sanz, Paula, Laurent, Adrien R G, Slot, Edith, Hoogenboezem, Mark, Bąbała, Nikolina, van Bruggen, Robin, Rongvaux, Anthony, Flavell, Richard A, Tytgat, Godelieve A M, Franke, Katka, Matlung, Hanke L, Kuijpers, Taco W, Amsen, Derk, Karrich, Julien J

“…MISTRG mice have been genetically modified to allow development of a human myeloid compartment from engrafted human CD34+ haemopoietic stem cells, making them…”
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Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells by Karrich, Julien J., Romera‐Hernández, Mónica, Papazian, Natalie, Veenbergen, Sharon, Cornelissen, Ferry, Aparicio‐Domingo, Patricia, Stenhouse, Frances H., Peddie, C. Diana, Hoogenboezem, Remco M., den Hollander, Chelsea W. J., Gaskell, Terri, Medley, Tanya, Boon, Louis, Blackburn, C. Clare, Withers, David R., Samsom, Janneke N., Cupedo, Tom

“…Under homeostatic conditions, dendritic cells (DCs) continuously patrol the intestinal lamina propria. Upon antigen encounter, DCs initiate C‐C motif chemokine…”
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The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the antiapoptotic gene BCL2-A1 by Karrich, Julien J., Balzarolo, Melania, Schmidlin, Heike, Libouban, Marion, Nagasawa, Maho, Gentek, Rebecca, Kamihira, Shimeru, Maeda, Takahiro, Amsen, Derk, Wolkers, Monika C., Blom, Bianca

“…Plasmacytoid dendritic cells (pDCs) selectively express Toll-like receptor (TLR)–7 and TLR-9, which allow them to rapidly secrete massive amounts of type I…”
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The transcriptional regulator NAB2 reveals a two‐step induction of TRAIL in activated plasmacytoid DCs by Balzarolo, Melania, Karrich, Julien J., Engels, Sander, Blom, Bianca, Medema, Jan Paul, Wolkers, Monika C.

“…Plasmacytoid dendritic cells (pDCs) are key players in antiviral immunity. In addition to massive type I interferon production, activated pDCs express the…”
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Group 3 innate lymphoid cells in tissue damage and graft-versus-host disease pathogenesis by Karrich, Julien J, Cupedo, Tom

“…Innate lymphoid cells (ILC) have emerged as modulators of conditioning-induced tissue damage and development of graft-versus-host disease (GVHD) in the context…”
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MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells by Karrich, Julien J., Jachimowski, Loes C.M., Libouban, Marion, Iyer, Anand, Brandwijk, Kim, Taanman-Kueter, Esther W., Nagasawa, Maho, de Jong, Esther C., Uittenbogaart, Christel H., Blom, Bianca

“…During microbial infections, plasmacytoid dendritic cells (pDCs) are a main source of type I interferons α/β (IFN-α/-β). Nucleic acids from microbes are sensed…”
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IL-21–stimulated human plasmacytoid dendritic cells secrete granzyme B, which impairs their capacity to induce T-cell proliferation by Karrich, Julien J., Jachimowski, Loes C.M., Nagasawa, Maho, Kamp, Angela, Balzarolo, Melania, Wolkers, Monika C., Uittenbogaart, Christel H., Marieke van Ham, S., Blom, Bianca

“…Plasmacytoid dendritic cells (pDCs) play a crucial role during innate immunity by secreting bulk amounts of type I interferons (IFNs) in response to Toll-like…”
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The transcriptional regulator NAB 2 reveals a two‐step induction of TRAIL in activated plasmacytoid DC s by Balzarolo, Melania, Karrich, Julien J., Engels, Sander, Blom, Bianca, Medema, Jan Paul, Wolkers, Monika C.

“…Plasmacytoid dendritic cells (p DC s) are key players in antiviral immunity. In addition to massive type I interferon production, activated p DC s express the…”
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Isolation and in vitro generation of gene-manipulated human plasmacytoid and conventional dendritic cells by Schotte, Remko, Schmidlin, Heike, Nagasawa, Maho, Dontje, Wendy, Karrich, Julien J, Uittenbogaart, Christel, Spits, Hergen, Blom, Bianca

“…Our understanding of human lymphocyte development has increased significantly over the past 20 years. In particular, our insight into human T- and B-cell…”
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In vivo modulation of gene expression by lentiviral transduction in "human immune system" Rag2-/- gamma c -/- mice by van Lent, Anja U, Centlivre, Mireille, Nagasawa, Maho, Karrich, Julien J, Pouw, Stephan M, Weijer, Kees, Spits, Hergen, Blom, Bianca, Legrand, Nicolas

“…Over the last two decades, several humanized mouse models have been used to experimentally analyze the function and development of the human immune system…”
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The plasmacytoid dendritic cell as the Swiss army knife of the immune system: Molecular regulation of their multifaceted functions by Karrich, Julien J., Jachimowski, Loes C. M., Uittenbogaart, Christel H., Blom, Bianca

“…Plasmacytoid dendritic cells (pDC) have been regarded as the “professional type I interferon producing cells” of the immune system following viral recognition…”
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Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103+ dendritic cells by Veenbergen, S, van Berkel, L A, du Pré, M F, He, J, Karrich, J J, Costes, L M M, Luk, F, Simons-Oosterhuis, Y, Raatgeep, H C, Cerovic, V, Cupedo, T, Mowat, A M, Kelsall, B L, Samsom, J N

“…Tolerance to harmless exogenous antigens is the default immune response in the gastrointestinal tract. Although extensive studies have demonstrated the…”
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Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage by Aparicio-Domingo, Patricia, Romera-Hernandez, Monica, Karrich, Julien J., Cornelissen, Ferry, Papazian, Natalie, Lindenbergh-Kortleve, Dicky J., Butler, James A., Boon, Louis, Coles, Mark C., Samsom, Janneke N., Cupedo, Tom

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