Search Results - "Karreth, F"
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Jun and JunD-dependent functions in cell proliferation and stress response
Published in Cell death and differentiation (01-09-2010)“…Jun is essential for fetal development, as fetuses lacking Jun die at mid-gestation with multiple cellular defects in liver and heart. Embryos expressing JunD…”
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Platelet-released supernatants stimulate formation of osteoclast-like cells through a prostaglandin/RANKL-dependent mechanism
Published in Bone (New York, N.Y.) (01-05-2002)“…Platelets are activated at fracture sites or upon the insertion of implants as a consequence of vascular disruption and secrete the contents of their granules…”
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The Fos-related antigen Fra-1 is an activator of bone matrix formation
Published in The EMBO journal (21-07-2004)“…Ectopic expression of the transcription factor Fra‐1 in transgenic mice leads to osteosclerosis, a bone disorder characterized by increased bone mass. The…”
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Mice Lacking JunB Are Osteopenic due to Cell-Autonomous Osteoblast and Osteoclast Defects
Published in The Journal of cell biology (16-02-2004)“…Because JunB is an essential gene for placentation, it was conditionally deleted in the embryo proper. junBΔ /Δmice are born viable, but develop severe low…”
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5
Twist induces an epithelial-mesenchymal transition to facilitate tumor metastasis
Published in Cancer biology & therapy (01-11-2004)“…Tumor metastasis--the spreading of primary tumor cells to distal organs--is the major cause of death of cancer patients. The metastatic process consists of…”
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Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions
Published in Platelets (Edinburgh) (01-02-2004)“…Platelet-rich plasma is currently promoted to serve as an adjuvant for bone grafts to enhance quantity and quality of newly forming bone; however, the…”
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JunD regulates lymphocyte proliferation and T helper cell cytokine expression
Published in The EMBO journal (24-03-2004)“…Transgenic mice broadly expressing JunD (Ubi‐junDm) appear phenotypically normal, but have strongly reduced numbers of peripheral lymphocytes. JunD…”
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The AP1 transcription factor Fra2 is required for efficient cartilage development
Published in Development (Cambridge) (01-11-2004)“…The Fos-related AP1 transcription factor Fra2 (encoded by Fosl2 ) is expressed in various epithelial cells as well as in cartilaginous structures. We studied…”
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Platelets are mitogenic for periosteum-derived cells
Published in Journal of orthopaedic research (01-09-2003)“…The early stages of bone regeneration are associated with a high mitogenic activity of periosteal cells. Here we addressed the question of whether platelets…”
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The AP1 transcription factor Fra2 is required for efficient cartilage development
Published in Development (Cambridge) (15-11-2005)“…The Fos-related AP1 transcription factor Fra2 (encoded by Fosl2) is expressed in various epithelial cells as well as in cartilaginous structures. We studied…”
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