Search Results - "Karpova, S S"
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Labeling Extracellular Vesicles for Nanoscale Flow Cytometry
Published in Scientific reports (12-05-2017)“…Extracellular vesicles (EVs), including exosomes and microvesicles, are 30–800 nm vesicles that are released by most cell types, as biological packages for…”
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Experience in implementing a mentorship program in the Nizhny Novgorod Oblast
Published in Kardiovaskuli͡a︡rnai͡a︡ terapii͡a︡ i profilaktika (01-06-2024)“…Retaining healthcare personnel through the implementation of medical mentoring aimed at adapting future healthcare professionals during training at a medical…”
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3
Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions
Published in Cell (21-04-2016)“…The estrogen receptor (ER), glucocorticoid receptor (GR), and forkhead box protein 1 (FoxA1) are significant factors in breast cancer progression. FoxA1 has…”
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4
DNA binding triggers tetramerization of the glucocorticoid receptor in live cells
Published in Proceedings of the National Academy of Sciences - PNAS (19-07-2016)“…Transcription factors dynamically bind to chromatin and are essential for the regulation of genes. Although a large percentage of these proteins appear to…”
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5
Single-molecule analysis of steroid receptor and cofactor action in living cells
Published in Nature communications (21-06-2017)“…Population-based assays have been employed extensively to investigate the interactions of transcription factors (TFs) with chromatin and are often interpreted…”
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MYC amplifies gene expression through global changes in transcription factor dynamics
Published in Cell reports (Cambridge) (25-01-2022)“…The MYC oncogene has been studied for decades, yet there is still intense debate over how this transcription factor controls gene expression. Here, we seek to…”
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Quantifying transcription factor binding dynamics at the single-molecule level in live cells
Published in Methods (San Diego, Calif.) (01-07-2017)“…•Single-molecule tracking acquires binding properties of transcription factors.•A detailed set-up to perform single molecule tracking is presented.•Challenges…”
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Impact of Saccharomyces cerevisiae on the Field of Single-Molecule Biophysics
Published in International journal of molecular sciences (14-12-2022)“…Cellular functions depend on the dynamic assembly of protein regulator complexes at specific cellular locations. Single Molecule Tracking (SMT) is a method of…”
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Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells
Published in Oncotarget (18-07-2017)“…Chromosomal instability (CIN) is a hallmark of many cancers and a major contributor to tumorigenesis. Centromere and kinetochore associated proteins such as…”
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10
Effect of Drug Encapsulation and Hydrothermal Exposure on the Structure and Molecular Dynamics of the Binary System Poly(3-hydroxybutyrate)-chitosan
Published in Polymers (10-05-2023)“…In this work, film materials based on binary compositions of poly-(3-hydroxybutyrate) (PHB) and chitosan with different ratios of polymer components in the…”
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Solvatochromic Sensitivity of BODIPY Probes: A New Tool for Selecting Fluorophores and Polarity Mapping
Published in International journal of molecular sciences (07-01-2023)“…This research work is devoted to collecting a high-quality dataset of BODIPYs in a series of 10-30 solvents. In total, 115 individual compounds in 71 solvents…”
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12
Measuring Chromatin Interaction Dynamics on the Second Time Scale at Single-Copy Genes
Published in Science (American Association for the Advancement of Science) (18-10-2013)“…The chromatin immunoprecipitation (ChIP) assay is widely used to capture interactions between chromatin and regulatory proteins, but it is unknown how stable…”
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13
Relative Telomere Length Is Associated with the Risk of Development and Severity of the Course of Age-Related Macular Degeneration in the Russian Population
Published in International journal of molecular sciences (01-07-2023)“…One of the most significant factors for age-related macular degeneration (AMD) development is considered to be aging, the processes of which are closely…”
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14
Development of a nasal spray containing aminocaproic acid and a copolymer of N-vinylpyrrolidone and 2-methyl-5-vinylpyridine for use in the prevention of influenza and other viral respiratory infections
Published in Tonkie himičeskie tehnologii (Online) (21-03-2020)“…Objectives . Prevention of influenza and viral respiratory infections is one of the major public health problems today. The aim of the study was to develop the…”
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15
Surface functional composition and sensor properties of ZnO, Fe2O3, and ZnFe2O4
Published in Semiconductors (Woodbury, N.Y.) (01-03-2013)“…Zinc and iron oxide (ZnO, Fe 2 O 3 ) and zinc ferrite (ZnFe 2 O 4 ) nanopowders are obtained by chemical co-precipitation. The gas-sensitive properties of…”
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16
Aggregation and Prion-Inducing Properties of the G-Protein Gamma Subunit Ste18 are Regulated by Membrane Association
Published in International journal of molecular sciences (16-07-2020)“…Yeast prions and mnemons are respectively transmissible and non-transmissible self-perpetuating protein assemblies, frequently based on cross-β ordered…”
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Structure and Properties of Biopolymeric Fibrous Materials Based on Polyhydroxybutyrate–Metalloporphyrin Complexes
Published in Russian journal of general chemistry (2021)“…Ultrathin fibrous materials based on natural bacterial polymer polyhydroxybutyrate (PHB) were prepared by the electrospinning method. Using scanning electron…”
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18
SUMO-1 Targets RanGAP1 to Kinetochores and Mitotic Spindles
Published in The Journal of cell biology (18-02-2002)“…RanGAP1 was the first documented substrate for conjugation with the ubiquitin-like protein SUMO-1. However, the functional significance of this conjugation has…”
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Prion Induction by the Short-Lived, Stress-Induced Protein Lsb2 Is Regulated by Ubiquitination and Association with the Actin Cytoskeleton
Published in Molecular cell (22-07-2011)“…Yeast prions are self-perpetuating, QN-rich amyloids that control heritable traits and serve as a model for mammalian amyloidoses. De novo prion formation by…”
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Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter
Published in Science (American Association for the Advancement of Science) (25-01-2008)“…For gene regulation, some transcriptional activators bind periodically to promoters with either a fast (~1 minute) or a slow (~15 to 90 minutes) cycle. It is…”
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