Search Results - "Karpov, A. P."
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Identification of FtsZ Interdomain Cleft Effectors Based on Pharmacophore Search and Molecular Docking
Published in Cytology and genetics (01-10-2024)“…There are a significant number of inhibitors of the bacterial FtsZ protein with biochemically confirmed biological activity, at the same time, their binding…”
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Ligand-Induced Variability of the FtsZ Protein Interdomain Site Pocket
Published in Cytology and genetics (01-08-2024)“…The variability of the allosteric binding site pocket located in the interdomain cleft (IDC) of FtsZ proteins was investigated. The point-cloud models of the…”
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Bioinformatical View on the Contribution of MAST/IRE-Dependent Phosphorylation in the Tubulin Code
Published in Cytology and genetics (2024)“…Protein kinases represent one of the largest eukaryotic enzyme superfamilies. However, only a few can directly phosphorylate tubulin and contribute to the…”
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Development of technology for culturing a cell line producing a single-domain antibody fused with the Fc fragment of human IgG1
Published in Tonkie himičeskie tehnologii (Online) (06-07-2024)“…Objectives. To develop an effective technology for the cultivation of Chinese hamster ovary (CHO) cells stably producing GamP2C5 antibody which is a component…”
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The Role of Posttranslational Acetylation in the Association of Autophagy Protein ATG8 with Microtubules in Plant Cells
Published in Cytology and genetics (01-11-2021)“…Our study was aimed to anlayze the mechanism of the effect of acetylation of the Lys40 residue in α-tubulin TUBA4 from A. thaliana on its structure and…”
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Is Casein Kinase 2 Able to Phosphorylate Plant α-Tubulin?
Published in Cytology and genetics (01-03-2018)“…Results of classical and structural bioinformatical research allow to predict casein kinase 2 dependent phosphorylation of conservative residues of Ser94 and…”
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3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana
Published in Journal of molecular modeling (01-11-2016)“…Histone lysine acetylation is a reversible post-translational modification that does not involve changes in DNA sequences. Enzymes play an important role in…”
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Structural Biological Characteristics of CK1-Like Protein Kinase Isotypes Associated with Regulation of Plant Microtubules
Published in Cytology and genetics (01-07-2020)“…Eighteen isotypes of CK1-like protein kinases were identified in A. thaliana . Comparison of catalytic domains in rat CK1 (α, β, γ1–3, δ, and ε) and 18 plant…”
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Studying the Role of Protein Kinases CK1 in Organization of Cortical Microtubules in Arabidopsis thaliana Root Cells
Published in Cytology and genetics (01-11-2019)“…The members of the casein kinase 1 (CK1) subfamily are distinguished by interspecific conservatism and an extensive set of phosphorylation substrates…”
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Motif-Based Prediction of Plant Tubulin Phosphorylation Sites Associated with Calcium-Dependent Protein Kinases in Arabidopsis thaliana
Published in Cytology and genetics (01-11-2018)“…New motifs for phosphorylation sites associated with calcium-dependent protein kinases were developed using 494 sites experimentally proved in mammalians…”
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Bioinformatic search for Ca2+- and calmodulin-dependent protein kinases potentially associated with the regulation of plant cytoskeleton
Published in Cytology and genetics (01-07-2017)“…The paper presents the results of a bioinformatic search for Ca 2+ - and calmodulin-dependent protein kinases from Arabidopsis thaliana , which may potentially…”
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Mechanical Properties of Structural Carbon-Carbon Layered Material at High Temperatures
Published in Inorganic materials : applied research (2019)“…The results of tensile and compression tests performed for a layered carbon-carbon material in the range of 20–3000°C are presented. The material has been…”
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Potential Involvement of KIN10 and KIN11 Catalytic Subunits of the SnRK1 Protein Kinase Complexes in the Regulation of Arabidopsis γ-Tubulin
Published in Cytology and genetics (01-09-2019)“…SnRK1 protein kinases are integral components of cell signaling involved in stress response, regulation of energy metabolism, seed germination and maturation,…”
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The Potential Role of SnRK1 Protein Kinases in the Regulation of Cell Division in Arabidopsis thaliana
Published in Cytology and genetics (01-05-2019)“…It is known that the sucrose nonfermenting-1 (SNF1)-related protein kinase (SnRK1) subfamily participates in the regulation of carbohydrate metabolism and…”
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Protein kinase KIN10 from Arabidopsis thaliana as a potential regulator of primary microtubule nucleation centers in plants
Published in Cytology and genetics (01-11-2017)“…The nearest plant homologues of animal protein kinase BRSK were identified using the methods of classical and structural bioinformatics. The selection was…”
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Problem of the formation of solid bitumens in the Tengiz deposit
Published in Lithology and Mineral Resources (01-03-2005)“…Results of long-term petrological and geochemical investigations of solid bitumens (SB) in the Tengiz deposit are presented. It has been established that they…”
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Bioinformatic search for plant homologs of the protein kinase Bub1--a key component of the mitotic spindle assembly checkpoint
Published in Cytology and genetics (2010)“…The bioinformatic search identified 14 plant homologs of the mitotic spindle assembly checkpoint protein kinase Bub1 of animals, yeasts, and myxomycetes. It…”
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Results of the clusterization of human microtubule and cell-cycle related serine/threonine protein kinases and their plant homologues
Published in Moscow University biological sciences bulletin (2010)“…We identified 191 plant homologues of human protein kinases involved in the phosphorylation of microtubular proteins and cell-cycle regulation. Using…”
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MAST2-like proteinkinase from grape Vitis vinifera: Cloning of catalytic domain cDNA
Published in Cytology and genetics (2010)“…During the work on the project on the identification of proteinkinases that phosphorylate protein microtubules of plants, we revealed with the help of…”
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