Search Results - "Karpenko, M N"
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Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson’s disease
Published in Cellular immunology (01-05-2018)“…•Elevated serum IL-1β and IL-6 and reduced IL-1RA levels were found in the PD group.•Increased CSF TNFα and serum IL-1β indicate rapid PD progression.•Serum…”
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The influenza A virus NS genome segment displays lineage-specific patterns in predicted RNA secondary structure
Published in BMC research notes (20-05-2016)“…Influenza A virus (IAV) is a segmented negative-sense RNA virus that causes seasonal epidemics and periodic pandemics in humans. Two regions (nucleotide…”
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Corrigendum to “Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson’s disease” [Cell. Immunol. 327 (2018) 77–82]
Published in Cellular immunology (01-12-2018)Get full text
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Antioxidant system alterations and physiological characteristics of neonatal and juvenile DAT‐KO rats
Published in Journal of neuroscience research (01-10-2023)“…Dopamine transporter knockout (DAT‐KO) rats represent a valuable rodent model for studying the molecular and phenotypical outcomes of the effects of excessive…”
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Protective effect of calpain inhibitors against manganese-induced toxicity in rats
Published in Metabolic brain disease (01-04-2022)“…Development of manganism is a major complication of manganese exposure in which neurological dysfunction is linked to accumulation of metal in the brain…”
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An Infection Hypothesis of Parkinson’s Disease
Published in Neuroscience and behavioral physiology (15-06-2019)“…Parkinson’s disease (PD) is a multifactorial progressive neurodegenerative disease characterized by predominant degeneration of dopaminergic neurons in the…”
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Role of Copper Dyshomeostasis in the Pathogenesis of Parkinson’s Disease
Published in Bulletin of experimental biology and medicine (01-03-2018)“…Serum concentration of copper, immunoreactive polypeptides of ceruloplasmin and its oxidase activity, and the number of copper atoms per ceruloplasmin molecule…”
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The Role of Calpains in Regulating Synaptic Transmission
Published in Neuroscience and behavioral physiology (01-10-2015)“…Calpains are Ca 2+ -dependent neutral cysteine proteases involved in the regulation of most physiological functions. Calpain substrates include receptors,…”
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Functional assessment of the nigrostriatal system in a rat preclinical model of Parkinson’s disease
Published in Journal of evolutionary biochemistry and physiology (01-09-2017)Get full text
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Changes in characteristics of sleep-wake cycle and motor activity at the preclinical stage of Parkinson's disease in old rats
Published in Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2018)“…To assess the changes in temporal characteristics and total motor activity (MA) during the sleep-wake cycle in old rats in the model of the preclinical stage…”
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GAP-43 Protein and Its Proteolytic Fragment in Spinal Cord Cells in Rats with Experimental Allergic Encephalomyelitis
Published in Neuroscience and behavioral physiology (01-06-2016)“…The limited regenerative capacity of the central nervous system (CNS) is one of the key factors promoting the development of neurodegenerative diseases,…”
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Clinical parameters and the level of certain cytokines in blood and cerebrospinal fluid of patients with Parkinson's disease
Published in Klinicheskaia meditsina (2015)“…In the past decade, much attention has been given to immunological mechanisms of development of Parkinson's disease with special reference to the role of pro-…”
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Microtubule-Associated Proteins as Indicators of Differentiation and the Functional State of Nerve Cells
Published in Neuroscience and behavioral physiology (01-03-2012)“…This review addresses the characteristics of the proteins beta-tubulin III, MAP2, and doublecortin, which are involved in the organization, stabilization, and…”
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Calpain Activity in Spinal Cord Cells from Rats with Experimental Allergic Encephalomyelitis of Different Grades
Published in Neuroscience and behavioral physiology (01-03-2011)“…The Ca 2+ -dependent calpain system of intracellular proteases is involved in regulating a multitude of physiological body functions. However, hyperactivation…”
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Analysis of the Morphological Signs of an Inflammatory Reaction in the Spinal Cord of Wistar Rats in an Experimental Model
Published in Neuroscience and behavioral physiology (2012)“…Morphological changes in the spinal cord were studied at the peak of development of experimental allergic encephalomyelitis in rats with different levels of…”
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Activity of calpaines in spinal cord cells of the rats with experimental allergic encephalomyelitis of different grades
Published in Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova (01-12-2009)“…In simulation of experimental allergic encephalomyelitis (EAE), a hyperactivation of calpaines occurs due to m-calpaines. The m-calpaines involvement in the…”
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Analysis of morphological manifestations of the inflammatory reaction in wistar rat spinal cord in experimental model
Published in Morfologiia (Saint Petersburg, Russia) (2010)“…Morphological changes in the spinal cord of rats with different intensity of pathological symptoms were studied at the peak of the experimental…”
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The role of calpains in the regulation of synaptic function
Published in Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova (01-04-2014)“…Calpains are calcium-activated neutral cysteine proteases, involved in the regulation of a number of physiological functions. Substrates of calpains include…”
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Content of Monoamines in the Pons Varolii in Experimental Post-Traumatic Stress Disorder
Published in Neurochemical journal (2020)“…—In posttraumatic stress disorder (PTSD), the development of anxiety symptoms correlates with an increase in the content of noradrenaline and dopamine and a…”
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GAP-43 and its proteolytic fragment in spinal cord cells of rats with experimental autoimmune encephalomyelitis
Published in Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova (01-01-2015)“…The regenerative capacity of the Central Nervous System (CNS) is a key factor implicated in the pathogenesis of neurodegenerative diseases. In the present…”
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