Search Results - "Karolina Kulig"
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Human Serum Albumin Aggregation/Fibrillation and its Abilities to Drugs Binding
Published in Molecules (Basel, Switzerland) (31-01-2020)“…Human serum albumin (HSA) is a protein that transports neutral and acid ligands in the organism. Depending on the environment's pH conditions, HSA can take one…”
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Spectroscopic Analysis of an Antimalarial Drug’s (Quinine) Influence on Human Serum Albumin Reduction and Antioxidant Potential
Published in Molecules (Basel, Switzerland) (01-09-2022)“…Quinine (Qi) is a well-known drug used in malaria therapy; it is also a potential anti-arrhythmic drug used in the treatment of calf cramps, rheumatoid…”
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3
Spectroscopic Studies of Quinobenzothiazine Derivative in Terms of the In Vitro Interaction with Selected Human Plasma Proteins: Part 2
Published in Molecules (Basel, Switzerland) (10-01-2023)“…Synthesis of anticancer substances and studying their binding abilities towards human serum proteins as carriers are important parts of pharmaceutical and…”
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New Synthetic Quinoline (Qui) Derivatives as Novel Antioxidants and Potential HSA's Antioxidant Activity Modulators-Spectroscopic Studies
Published in Molecules (Basel, Switzerland) (30-12-2022)“…The antioxidant activity of drugs, as well as the influence of drugs on the activity of endogenous antioxidant mechanisms in the human body is of great…”
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Changes in Glycated Human Serum Albumin Binding Affinity for Losartan in the Presence of Fatty Acids In Vitro Spectroscopic Analysis
Published in Molecules (Basel, Switzerland) (08-01-2022)“…Conformational changes in human serum albumin due to numerous modifications that affect its stability and biological activity should be constantly monitored,…”
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Spectroscopic Studies of Quinobenzothiazine Derivative in Terms of the In Vitro Interaction with Selected Human Plasma Proteins. Part 1
Published in Molecules (Basel, Switzerland) (06-08-2021)“…Plasma proteins play a fundamental role in living organisms. They participate in the transport of endogenous and exogenous substances, especially drugs…”
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Comparison of Losartan and Furosemide Interaction with HSA and Their Influence on HSA Antioxidant Potential
Published in Pharmaceuticals (Basel, Switzerland) (19-04-2022)“…Serum albumin (HSA) is the most important protein in human body. Due to the antioxidant activity, HSA influences homeostasis maintenance and transport of drugs…”
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Circular Dichroism as a Rapid Method for Analyzing the Binding of a Targeting Ligand to the Surface of Albumin Nanoparticles
Published in Pharmaceuticals (Basel, Switzerland) (01-10-2023)“…Circular dichroism (CD) is an excellent and rapid method for analysis of chiral molecules, whose mechanism is based on the absorption of left- and right-hand…”
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The Influence of Oxidative Stress on Serum Albumin Structure as a Carrier of Selected Diazaphenothiazine with Potential Anticancer Activity
Published in Pharmaceuticals (Basel, Switzerland) (23-03-2021)“…Albumin is one of the most important proteins in human blood. Among its multiple functions, drug binding is crucial in terms of drug distribution in human…”
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In vitro spectroscopic studies of 9-amino-5-alkyl-12(H)-quino[3,4-b][1,4]benzothiazine chloride with main carrier plasma proteins
Published in Chemico-biological interactions (05-01-2025)“…Current methods of cancer treatment, particularly chemotherapy, are associated with harmful side effects. For this reason, it is significant to study new…”
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11
Ligand-human serum albumin analysis: the near-UV CD and UV-Vis spectroscopic studies
Published in Naunyn-Schmiedeberg's archives of pharmacology (30-09-2024)“…Spectroscopic methods offer many new opportunities to study protein-ligand interactions. The aim of this study was to evaluate the possibility of using near-UV…”
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Antioxidant and reducing activity of Tilia cordata honey produced by Apis mellifera compared to inflorescence Tilia cordata infusion and their mixtures
Published in Journal of apicultural research (19-10-2024)“…Herbal and apiculture preparations are examples of products with a very long history of medicine and human body care use. This study aimed to compare the…”
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In vitro spectroscopic studies of 9-amino-5-alkyl-12(H)-quino3,4-b1,4benzothiazine chloride with main carrier plasma proteins
Published in Chemico-biological interactions (23-10-2024)“…Current methods of cancer treatment, particularly chemotherapy, are associated with harmful side effects. For this reason, it is significant to study new…”
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14
In vitro spectroscopic studies of 9-amino-5-alkyl-12(H)-quino[3,4-b][1,4]benzothiazine chloride with main carrier plasma proteins
Published in Chemico-biological interactions (23-10-2024)“…Current methods of cancer treatment, particularly chemotherapy, are associated with harmful side effects. For this reason, it is significant to study new…”
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15
Bovine Serum Albumin Nanoparticles as a Proposed Drug Formulation for the Delivery of 10H-2,7-diazaphenothiazine
Published in Journal of cluster science (01-10-2024)“…The synthesis of new compounds and nanoparticles is one of many attempts to circumvent the drug resistance. Albumin nanoparticles are biocompatible drug…”
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Evaluation of TLR4 expression and chosen parameters of oxidative-antioxidative balance in young children with food allergy
Published in Folia histochemica et cytobiologica (01-11-2010)“…The authors evaluated mRNA TLR4 expression on neutrophils and the chosen parameters of oxidative-antioxidative balance in blood of 35 children with food…”
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Evaluation of TLR4 expression and chosen parameters of oxidative-antioxidative balance in young children with food allergy
Published in Folia histochemica et cytobiologica (30-09-2010)“…The authors evaluated mRNA TLR4 expression on neutrophils and the chosen parameters of oxidative-antioxidative balance in blood of 35 children with food…”
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TLR4 receptor and selected cytokines in development of food allergy in infants and small children
Published in Przegląd gastroenterologiczny (2011)Get full text
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19
The coexistence of atopic dermatitis and psoriasis in a 12 months-old girl
Published in Polski merkuriusz lekarski (01-10-2005)“…The coexistence of atopic dermatitis and psoriasis is especially rare diagnosed disease in small children. Authors present a 12 months-old girl with both of…”
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The diagnostic difficulties in children with allergic skin changes and parvovirus B19 infection. Own experiences
Published in Medycyna wieku rozwojowego (01-07-2006)“…The authors describe two children with similar skin changes, which have been provoked by two different diseases-atopic dermatitis and parvovirosis B19. The…”
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