Search Results - "Karolak, Michele J"

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  1. 1

    FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney by Fetting, Jennifer L, Guay, Justin A, Karolak, Michele J, Iozzo, Renato V, Adams, Derek C, Maridas, David E, Brown, Aaron C, Oxburgh, Leif

    Published in Development (Cambridge) (01-01-2014)
    “…Forkhead transcription factors are essential for diverse processes in early embryonic development and organogenesis. Foxd1 is required during kidney…”
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  2. 2

    BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanism by Blank, Ulrika, Brown, Aaron, Adams, Derek C, Karolak, Michele J, Oxburgh, Leif

    Published in Development (Cambridge) (01-11-2009)
    “…The iterative formation of nephrons during embryonic development relies on continual replenishment of progenitor cells throughout nephrogenesis. Defining…”
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  3. 3

    Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron by Lindström, Nils O, Lawrence, Melanie L, Burn, Sally F, Johansson, Jeanette A, Bakker, Elvira R M, Ridgway, Rachel A, Chang, C-Hong, Karolak, Michele J, Oxburgh, Leif, Headon, Denis J, Sansom, Owen J, Smits, Ron, Davies, Jamie A, Hohenstein, Peter

    Published in eLife (03-02-2015)
    “…The different segments of the nephron and glomerulus in the kidney balance the processes of water homeostasis, solute recovery, blood filtration, and…”
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  4. 4

    Chordin-like 1 and Twisted Gastrulation 1 Regulate BMP Signaling following Kidney Injury by LARMAN, Barry W, KAROLAK, Michele J, ADAMS, Derek C, OXBURGH, Leif

    “…Stimulation of the bone morphogenetic protein (BMP) pathway protects the kidney from acute and chronic injury. Numerous regulators in the kidney control BMP…”
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  5. 5

    An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney by Blank, Ulrika, Seto, Marianne L, Adams, Derek C, Wojchowski, Don M, Karolak, Michele J, Oxburgh, Leif

    Published in BMC developmental biology (18-09-2008)
    “…Bone morphogenetic proteins (BMPs) regulate essential processes during organogenesis, and a functional understanding of these secreted proteins depends on…”
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  6. 6

    Inactivation of MAP3K7 in FOXD1-expressing cells results in loss of mesangial PDGFRΒ and juvenile kidney scarring by Karolak, Michele J, Guay, Justin A, Oxburgh, Leif

    “…Transforming growth factor-β (TGFβ) plays a central role in renal scarring, controlling extracellular matrix deposition by interstitial cells and mesangial…”
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  7. 7

    Follistatin-like 1 regulates renal IL-1β expression in cisplatin nephrotoxicity by Adams, Derek C, Karolak, Michele J, Larman, Barry W, Liaw, Lucy, Nolin, James D, Oxburgh, Leif

    “…Follistatin-like 1 (FSTL1) is a secreted protein with homology to both Follistatin and the SPARC/BM40 family of matricellular proteins. In this study, we…”
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  8. 8

    Distinct bone morphogenetic proteins activate indistinguishable transcriptional responses in nephron epithelia including Notch target genes by Larman, Barry W., Karolak, Michele J., Lindner, Volkhard, Oxburgh, Leif

    Published in Cellular signalling (01-01-2012)
    “…Endogenous Bone Morphogenetic Protein (BMP) signaling plays a significant role in the kidney's recovery from acute injury and exogenous administration of BMP7…”
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  9. 9

    Isolation and culture of cells from the nephrogenic zone of the embryonic mouse kidney by Brown, Aaron C, Blank, Ulrika, Adams, Derek C, Karolak, Michele J, Fetting, Jennifer L, Hill, Beth L, Oxburgh, Leif

    Published in Journal of visualized experiments (22-04-2011)
    “…Embryonic development of the kidney has been extensively studied both as a model for epithelial-mesenchymal interaction in organogenesis and to gain…”
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  10. 10

    Kinetics of Transmission, Infectivity, and Genome Stability of Two Novel Mouse Norovirus Isolates in Breeding Mice by Kelmenson, Jennifer A, Pomerleau, Darcy P, Griffey, Stephen, Zhang, Weidong, Karolak, Michele J, Fahey, James R

    Published in Comparative medicine (01-02-2009)
    “…Murine noroviruses are a recently discovered group of viruses found within mouse research colonies in many animal facilities worldwide. In this study, we used…”
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