Search Results - "Karolak, Michele J"
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FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney
Published in Development (Cambridge) (01-01-2014)“…Forkhead transcription factors are essential for diverse processes in early embryonic development and organogenesis. Foxd1 is required during kidney…”
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BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanism
Published in Development (Cambridge) (01-11-2009)“…The iterative formation of nephrons during embryonic development relies on continual replenishment of progenitor cells throughout nephrogenesis. Defining…”
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Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron
Published in eLife (03-02-2015)“…The different segments of the nephron and glomerulus in the kidney balance the processes of water homeostasis, solute recovery, blood filtration, and…”
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Chordin-like 1 and Twisted Gastrulation 1 Regulate BMP Signaling following Kidney Injury
Published in Journal of the American Society of Nephrology (01-05-2009)“…Stimulation of the bone morphogenetic protein (BMP) pathway protects the kidney from acute and chronic injury. Numerous regulators in the kidney control BMP…”
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An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney
Published in BMC developmental biology (18-09-2008)“…Bone morphogenetic proteins (BMPs) regulate essential processes during organogenesis, and a functional understanding of these secreted proteins depends on…”
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Inactivation of MAP3K7 in FOXD1-expressing cells results in loss of mesangial PDGFRΒ and juvenile kidney scarring
Published in American journal of physiology. Renal physiology (01-08-2018)“…Transforming growth factor-β (TGFβ) plays a central role in renal scarring, controlling extracellular matrix deposition by interstitial cells and mesangial…”
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Follistatin-like 1 regulates renal IL-1β expression in cisplatin nephrotoxicity
Published in American journal of physiology. Renal physiology (01-12-2010)“…Follistatin-like 1 (FSTL1) is a secreted protein with homology to both Follistatin and the SPARC/BM40 family of matricellular proteins. In this study, we…”
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Distinct bone morphogenetic proteins activate indistinguishable transcriptional responses in nephron epithelia including Notch target genes
Published in Cellular signalling (01-01-2012)“…Endogenous Bone Morphogenetic Protein (BMP) signaling plays a significant role in the kidney's recovery from acute injury and exogenous administration of BMP7…”
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Isolation and culture of cells from the nephrogenic zone of the embryonic mouse kidney
Published in Journal of visualized experiments (22-04-2011)“…Embryonic development of the kidney has been extensively studied both as a model for epithelial-mesenchymal interaction in organogenesis and to gain…”
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Kinetics of Transmission, Infectivity, and Genome Stability of Two Novel Mouse Norovirus Isolates in Breeding Mice
Published in Comparative medicine (01-02-2009)“…Murine noroviruses are a recently discovered group of viruses found within mouse research colonies in many animal facilities worldwide. In this study, we used…”
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Isolation and Culture of Cells from the Nephrogenic Zone of the Embryonic Mouse Kidney
Published in Journal of visualized experiments (22-04-2011)Get full text
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