Search Results - "Karnik, Pallavi V."
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Synthesis and pharmacological evaluation of novel N-aryl-3,4-dihydro-1′H-spiro[chromene-2,4′-piperidine]-1′-carboxamides as TRPM8 antagonists
Published in Bioorganic & medicinal chemistry (01-11-2013)“…Compound (4R)-(–)-10e showed favorable PK profile and excellent efficacy in rodent models of neuropathic pain upon oral dosing. A novel series of…”
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Synthesis and pharmacological evaluation of novel N-aryl-3,4-dihydro-1'H-spiro[chromene-2,4'-piperidine]-1'-carboxamides as TRPM8 antagonists
Published in Bioorganic & medicinal chemistry (01-11-2013)“…A novel series of N-aryl-3,4-dihydro-1'H-spiro[chromene-2,4'-piperidine]-1'-carboxamides was identified as transient receptor potential melastatin 8 (TRPM8)…”
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Journal Article