Search Results - "Karni, S."

Mitochondrial bound PKA contributes to cyclic-AMP compartmentation in human airway smooth muscle cells by Sherpa, Rinzhin Tshering, Moshal, Karni S., Agarwal, Shailesh R., Ostrom, Rennolds S., Harvey, Robert D.

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Role of mitochondrial pka in compartmentation of cAMP signaling in cardiac ventricular myocytes by Tshering Sherpa, Rinzhin, Moshal, Karni S., Agarwal, Shailesh R., Harvey, Robert D.

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Compartmentalized cAMP signaling in cardiac ventricular myocytes by Agarwal, Shailesh R., Sherpa, Rinzhin T., Moshal, Karni S., Harvey, Robert D.

“…Activation of different receptors that act by generating the common second messenger cyclic adenosine monophosphate (cAMP) can elicit distinct functional…”
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Role of protein kinase A and A kinase anchoring proteins in buffering and compartmentation of cAMP signalling in human airway smooth muscle cells by Sherpa, Rinzhin T., Moshal, Karni S., Agarwal, Shailesh R., Ostrom, Rennolds S., Harvey, Robert D.

“…Background and Purpose In human airway smooth muscle (hASM) cells, not all receptors stimulating cAMP production elicit the same effects. This can only be…”
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Mechanisms of homocysteine-induced oxidative stress by Tyagi, Neetu, Sedoris, Kara C, Steed, Mesia, Ovechkin, Alexander V, Moshal, Karni S, Tyagi, Suresh C

“…Hyperhomocysteinemia decreases vascular reactivity and is associated with cardiovascular morbidity and mortality. However, pathogenic mechanisms that increase…”
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H2S protects against methionine-induced oxidative stress in brain endothelial cells by Tyagi, Neetu, Moshal, Karni S, Sen, Utpal, Vacek, Thomas P, Kumar, Munish, Hughes, Jr, William M, Kundu, Soumi, Tyagi, Suresh C

“…Homocysteine (Hcy) causes cerebrovascular dysfunction by inducing oxidative stress. However, to date, there are no strategies to prevent Hcy-induced oxidative…”
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Corrigendum: Three-week-old rabbit ventricular cardiomyocytes as a novel system to study cardiac excitation and EC coupling by Kabakov, Anatoli Y, Sengun, Elif, Lu, Yichun, Roder, Karim, Bronk, Peter, Baggett, Brett, Turan, Nilüfer N, Moshal, Karni S, Koren, Gideon

“…[This corrects the article DOI: 10.3389/fphys.2021.672360.]…”
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Endogenous Hyaluronan Promotes Intestinal Homeostasis and Protects against Murine Necrotizing Enterocolitis by Eckert, Jeffery V, Moshal, Karni S, Burge, Kathryn, Wilson, Adam, Chaaban, Hala

“…Necrotizing enterocolitis (NEC) is a complex, multifactorial gastrointestinal disorder predominantly affecting preterm infants. The pathogenesis of this…”
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Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling by Kabakov, Anatoli Y, Sengun, Elif, Lu, Yichun, Roder, Karim, Bronk, Peter, Baggett, Brett, Turan, Nilüfer N, Moshal, Karni S, Koren, Gideon

“…Cardiac arrhythmias significantly contribute to cardiovascular morbidity and mortality. The rabbit heart serves as an accepted model system for studying…”
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Compartmentation of β2‐adrenoceptor stimulated cAMP responses by phosphodiesterase types 2 and 3 in cardiac ventricular myocytes by Rudokas, Michael W., Post, John P., Sataray‐Rodriguez, Alejandra, Sherpa, Rinzhin T., Moshal, Karni S., Agarwal, Shailesh R., Harvey, Robert D.

“…Background and Purpose In cardiac myocytes, cyclic AMP (cAMP) produced by both β1‐ and β2‐adrenoceptors increases L‐type Ca2+ channel activity and myocyte…”
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The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2 by Turan, Nilüfer N., Moshal, Karni S., Roder, Karim, Baggett, Brett C., Kabakov, Anatoli Y., Dhakal, Saroj, Teramoto, Ryota, Chiang, David Yi-Eng, Zhong, Mingwang, Xie, An, Lu, Yichun, Dudley, Samuel C., MacRae, Calum A., Karma, Alain, Koren, Gideon

“…The QT interval is a recording of cardiac electrical activity. Previous genome-wide association studies identified genetic variants that modify the QT interval…”
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Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL) by Roder, Karim, Kabakov, Anatoli, Moshal, Karni S., Murphy, Kevin R., Xie, An, Dudley, Samuel, Turan, Nilüfer N., Lu, Yichun, MacRae, Calum A., Koren, Gideon

“…The QT interval is an important diagnostic feature on surface electrocardiograms because it reflects the duration of the ventricular action potential. A…”
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Analyzing efficiency of a lentiviral shRNA knockdown system in human enteroids using western blot and flow cytometry by Wilson, Adam P., Moshal, Karni S., Franca, Addison P., Ramani, Sasirekha, Gallucci, Randle, Chaaban, Hala, Burge, Kathryn Y.

“…Enteroids are in vitro models to study gastrointestinal pathologies and test personalized therapeutics; however, the inherent complexity of enteroids often…”
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Compartmentation of β 2 -adrenoceptor stimulated cAMP responses by phosphodiesterase types 2 and 3 in cardiac ventricular myocytes by Rudokas, Michael W, Post, John P, Sataray-Rodriguez, Alejandra, Sherpa, Rinzhin T, Moshal, Karni S, Agarwal, Shailesh R, Harvey, Robert D

“…In cardiac myocytes, cyclic AMP (cAMP) produced by both β - and β -adrenoceptors increases L-type Ca channel activity and myocyte contraction. However, only…”
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Mitochondrial A‐kinase anchoring proteins in cardiac ventricular myocytes by Sherpa, Rinzhin T., Fiore, Chase, Moshal, Karni S., Wadsworth, Adam, Rudokas, Michael W., Agarwal, Shailesh R., Harvey, Robert D.

“…Compartmentation of cAMP signaling is a critical factor for maintaining the integrity of receptor‐specific responses in cardiac myocytes. This phenomenon…”
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Ginger stimulates hematopoiesis via Bmp pathway in zebrafish by Ferri-Lagneau, Karine F, Moshal, Karni S, Grimes, Matthew, Zahora, Braden, Lv, Lishuang, Sang, Shengmin, Leung, Tinchung

“…Anemia is a hematologic disorder with decreased number of erythrocytes. Erythropoiesis, the process by which red blood cells differentiate, are conserved in…”
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Water wave propagation in unbounded domains. Part I: Nonreflecting boundaries by Jennings, G.I., Karni, S., Rauch, J.B.

“…This paper concerns non-reflecting boundary conditions for linearized 2D incompressible, irrotational, inviscid free surface flows in deep water. The…”
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Mitochondrial mechanism of microvascular endothelial cells apoptosis in hyperhomocysteinemia by Tyagi, Neetu, Ovechkin, Alexander V., Lominadze, David, Moshal, Karni S., Tyagi, Suresh C.

“…An elevated level of homocysteine (Hcy) limits the growth and induces apoptosis. However, the mechanism of Hcy‐induced programmed cell death in endothelial…”
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Progesterone modulates SERCA2a expression and function in rabbit cardiomyocytes by Moshal, Karni S, Zhang, Zhe, Roder, Karim, Kim, Tae Yun, Cooper, Leroy, Patedakis Litvinov, Bogdan, Lu, Yichun, Reddy, Vishal, Terentyev, Dmitry, Choi, Bum-Rak, Koren, Gideon

“…We recently showed that progesterone treatment abolished arrhythmias and sudden cardiac death in a transgenic rabbit model of long QT syndrome type 2 (LQT2)…”
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Homocysteine causes cerebrovascular leakage in mice by Lominadze, David, Roberts, Andrew M, Tyagi, Neetu, Moshal, Karni S, Tyagi, Suresh C

“…Elevated plasma homocysteine (Hcy) is associated with cerebrovascular disease and activates matrix metalloproteinases (MMPs), which lead to vascular remodeling…”
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