Search Results - "Karna, S."

Pseudomonas aeruginosa transcriptome adaptations from colonization to biofilm infection of skin wounds by D’Arpa, Peter, Karna, S. L. Rajasekhar, Chen, Tsute, Leung, Kai P.

“…In burn patients Pseudomonas aeruginosa infection is a major cause of morbidity. Analysis of the pathogen’s gene expression as it transitions from colonization…”
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Borrelia host adaptation Regulator (BadR) regulates rpoS to modulate host adaptation and virulence factors in Borrelia burgdorferi by Miller, Christine L., Karna, S. L. Rajasekhar, Seshu, J.

“…Summary The RpoS transcription factor of Borrelia burgdorferi is a ‘gatekeeper’ because it activates genes required for spirochaetes to transition from tick to…”
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RNA-Seq Transcriptomic Responses of Full-Thickness Dermal Excision Wounds to Pseudomonas aeruginosa Acute and Biofilm Infection by Karna, S L Rajasekhar, D'Arpa, Peter, Chen, Tsute, Qian, Li-Wu, Fourcaudot, Andrea B, Yamane, Kazuyoshi, Chen, Ping, Abercrombie, Johnathan J, You, Tao, Leung, Kai P

“…Pseudomonas aeruginosa infections of wounds in clinical settings are major complications whose outcomes are influenced by host responses that are not…”
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Pirfenidone regulates LPS mediated activation of neutrophils by Evani, Shankar J., Karna, S. L. Rajasekhar, Seshu, Janakiram, Leung, Kai P.

“…Excessive inflammation or its absence may result in impaired wound healing. Neutrophils are among the first innate immune cells to arrive at the injury site…”
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Formation of Pseudomonas aeruginosa Biofilms in Full-thickness Scald Burn Wounds in Rats by Brandenburg, Kenneth S., Weaver, Alan J., Karna, S. L. Rajasekhar, You, Tao, Chen, Ping, Stryk, Shaina Van, Qian, Liwu, Pineda, Uzziel, Abercrombie, Johnathan J., Leung, Kai P.

“…Using Sprague-Dawley rats (350–450 g; n = 61) and the recently updated Walker-Mason rat scald burn model, we demonstrated that Pseudomonas aeruginosa readily…”
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Length–weight and length–length relationship of Thryssa purava (Hamilton, 1822), Thryssa polybranchialis Wongratana, 1983 and Thryssa mystax (Bloch & Schneider, 1801) from Chilika lagoon, India by Karna, S. K.

“…Summary Current study provides basic information on Length–weight relationship (LWR) and length‐length relationship (LLR) of three fish species of genus…”
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Borrelia Host Adaptation Protein (BadP) Is Required for the Colonization of a Mammalian Host by the Agent of Lyme Disease by Smith, Trever C., Helm, Sarah M., Chen, Yue, Lin, Ying-Han, Rajasekhar Karna, S. L., Seshu, J.

“…ABSTRACT Borrelia burgdorferi , the agent of Lyme disease (LD), uses host-derived signals to modulate gene expression during the vector and mammalian phases of…”
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Performance of prognostic scores in prediction of 30-day postoperative mortality in COVID-19 patients after emergency surgery: A retrospective cohort study by Karna, S, Gouroumourty, R, Ahmad, Z, Trivedi, S, Thaware, P, Singh, P

“…Background: Risk assessment with prognostic scoring, though important, is scarcely studied in emergency surgical patients with COVID-19 infection. Methods and…”
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Short-Chain Fatty Acids Alter Metabolic and Virulence Attributes of Borrelia burgdorferi by Lin, Ying-Han, Chen, Yue, Smith, 2nd, Trever C, Karna, S L Rajasekhar, Seshu, J

“…responds to a variety of host-derived factors and appropriately alters its gene expression for adaptation under different host-specific conditions. We…”
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The impact of simultaneous inoculation of Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans on rodent burn wounds by Brandenburg, Kenneth S., Weaver, Alan J., Karna, S.L. Rajasekhar, Leung, Kai P.

“…•P. aeruginosa and S. aureus formed biofilms and coexisted in burn wounds.•The combined bacterial and host pressure restricted growth of C. albicans.•P…”
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Evaluation of analgesic interaction between morphine, maropitant and dexmedetomidine in dogs undergoing ovariohysterectomy by Karna, SR, Chambers, P, Singh, P, Lopez-Villalobos, N, Kongara, K

“…To compare the analgesic effect of morphine combined with maropitant and/or dexmedetomidine to morphine alone but at a higher dose, and to evaluate the…”
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Anesthetic challenges while performing emergency laparotomy in a patient having COVID-19 infection by Karna, S, Kumari, S, Singh, P, Waindeskar, V

“…An elderly hypertensive lady presented with fever, respiratory symptoms, and mild abdominal discomfort and was diagnosed to have COVID-19 pneumonia…”
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CsrA Modulates Levels of Lipoproteins and Key Regulators of Gene Expression Critical for Pathogenic Mechanisms of Borrelia burgdorferi by Karna, S.L. Rajasekhar, Sanjuan, Eva, Esteve-Gassent, Maria D, Miller, Christine L, Maruskova, Mahulena, Seshu, J

“…Carbon storage regulator A (CsrA) is an RNA binding protein that has been characterized in many bacterial species to play a central regulatory role by…”
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Comparative Transcriptome Analysis of Superficial and Deep Partial-Thickness Burn Wounds in Yorkshire vs Red Duroc Pigs by Nguyen, Jesse Q, Sanjar, Fatemeh, Rajasekhar Karna, S L, Fourcaudot, Andrea B, Wang, Li-Ju, Silliman, David T, Lai, Zhao, Chen, Yidong, Leung, Kai P

“…Abstract Hypertrophic scars are a common negative outcome of deep partial-thickness (DPT) burn wounds resulting in increased dermal thickness, wound area…”
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Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi by Van Laar, Tricia A, Lin, Ying-Han, Miller, Christine L, Karna, S L Rajasekhar, Chambers, James P, Seshu, J

“…Borrelia burgdorferi, the agent of Lyme disease, is a spirochetal pathogen with limited metabolic capabilities that survives under highly disparate…”
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Development of Pseudomonas aeruginosa Biofilms in Partial-Thickness Burn Wounds Using a Sprague-Dawley Rat Model by Brandenburg, Kenneth S, Weaver, Alan J, Qian, Liwu, You, Tao, Chen, Ping, Karna, S L Rajasekhar, Fourcaudot, Andrea B, Sebastian, Eliza A, Abercrombie, Johnathan J, Pineda, Uzziel, Hong, Jinson, Wienandt, Nathan A, Leung, Kai P

“…Abstract We used a modified Walker–Mason scald burn rat model to demonstrate that Pseudomonas aeruginosa, a common opportunistic pathogen in the burn ward and…”
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Contributions of Environmental Signals and Conserved Residues to the Functions of Carbon Storage Regulator A of Borrelia burgdorferi by Karna, S L Rajasekhar, Prabhu, Rajesh G, Lin, Ying-Han, Miller, Christine L, Seshu, J

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Creation of deletion and insertion clonal complex 8 Staphylococcus aureus mutants using a common cloning vector by Chen, Ping, Karna, S.L.Rajasekhar, Leung, Kai P.

“…Deletion and insertion clonal complex 8 Staphylococcus aureus mutants were created without using intermediate host S. aureus RN4220 or temperature-sensitive…”
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Cerium Nitrate Stiffens In Vitro Skin Models and Reduces Pseudomonas aeruginosa Pathogenicity and Penetration Through Skin Models by Evani, Shankar J, Chen, Ping, Karna, S L Rajasekhar, D'Arpa, Peter, Leung, Kai P

“…Cerium nitrate (CeN) plus silver sulfadiazine (SSD) cream has been used for 40-plus years to manage burns. CeN produces a hardened eschar believed to resist…”
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T3SS and alginate biosynthesis of Pseudomonas aeruginosa impair healing of infected rabbit wounds by Karna, S. L. Rajasekhar, Nguyen, Jesse Q., Evani, Shankar Jaikishan, Qian, Li-Wu, Chen, Ping, Abercrombie, Johnathan J., Sebastian, Eliza A., Fourcaudot, Andrea B., Leung, Kai P.

“…Pseudomonas aeruginosa (a Gram-negative bacterium) is an opportunistic pathogen found in many infected wounds and is known to impair healing. To test the…”
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