Search Results - "Karlström, Amelie Eriksson"

Affibody Molecules in Biotechnological and Medical Applications by Ståhl, Stefan, Gräslund, Torbjörn, Eriksson Karlström, Amelie, Frejd, Fredrik Y, Nygren, Per-Åke, Löfblom, John

“…Affibody molecules are small (6.5-kDa) affinity proteins based on a three-helix bundle domain framework. Since their introduction 20 years ago as an…”
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Photocontrolled Reversible Binding between the Protein A‑Derived Z Domain and Immunoglobulin G by Myrhammar, Anders, Rosik, Daniel, Karlström, Amelie Eriksson

“…Photoisomerization of the trans and cis isomers of azobenzene derivatives has been used to control the function of biomolecules in a reversible and…”
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Site-Specific Photoconjugation of Antibodies Using Chemically Synthesized IgG-Binding Domains by Perols, Anna, Karlström, Amelie Eriksson

“…Site-specific labeling of antibodies can be performed using the immunoglobulin-binding Z domain, derived from staphylococcal protein A (SpA), which has a…”
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Fast and Efficient Fc-Specific Photoaffinity Labeling To Produce Antibody–DNA Conjugates by Stiller, Christiane, Aghelpasand, Hooman, Frick, Tobias, Westerlund, Kristina, Ahmadian, Afshin, Karlström, Amelie Eriksson

“…Antibody–DNA conjugates are powerful tools for DNA-assisted protein analysis. Growing usage of these methods demands efficient production of high-quality…”
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Affibody-Mediated PNA-Based Pretargeted Cotreatment Improves Survival of Trastuzumab-Treated Mice Bearing HER2-Expressing Xenografts by Oroujeni, Maryam, Tano, Hanna, Vorobyeva, Anzhelika, Liu, Yongsheng, Vorontsova, Olga, Xu, Tianqi, Westerlund, Kristina, Orlova, Anna, Tolmachev, Vladimir, Karlström, Amelie Eriksson

“…Treatment of patients with human epidermal growth factor receptor 2 (HER2)-expressing tumors using the monoclonal antibody trastuzumab increases survival. The…”
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Stability Enhancement of a Dimeric HER2-Specific Affibody Molecule through Sortase A-Catalyzed Head-to-Tail Cyclization by Westerlund, Kristina, Myrhammar, Anders, Tano, Hanna, Gestin, Maxime, Karlström, Amelie Eriksson

“…Natural backbone-cyclized proteins have an increased thermostability and resistance towards proteases, characteristics that have sparked interest in…”
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Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle by Westerlund, Kristina, Altai, Mohamed, Mitran, Bogdan, Konijnenberg, Mark, Oroujeni, Maryam, Atterby, Christina, de Jong, Marion, Orlova, Anna, Mattsson, Johanna, Micke, Patrick, Karlström, Amelie Eriksson, Tolmachev, Vladimir

“…Affibody molecules are small proteins engineered using a nonantibody scaffold. Radiolabeled Affibody molecules are excellent imaging probes, but their…”
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Covalent Immunoglobulin Labeling through a Photoactivable Synthetic Z Domain by Konrad, Anna, Eriksson Karlström, Amelie, Hober, Sophia

“…Traditionally, labeling of antibodies has been performed by covalent conjugation to amine or carboxyl groups. These methods are efficient but suffer from…”
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Exploiting Electrostatic Interaction for Highly Sensitive Detection of Tumor-Derived Extracellular Vesicles by an Electrokinetic Sensor by Sahu, Siddharth Sourabh, Cavallaro, Sara, Hååg, Petra, Nagy, Ábel, Karlström, Amelie Eriksson, Lewensohn, Rolf, Viktorsson, Kristina, Linnros, Jan, Dev, Apurba

“…We present an approach to improve the detection sensitivity of a streaming current-based biosensor for membrane protein profiling of small extracellular…”
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Site-specific conjugation of recognition tags to trastuzumab for peptide nucleic acid-mediated radionuclide HER2 pretargeting by Westerlund, Kristina, Vorobyeva, Anzhelika, Mitran, Bogdan, Orlova, Anna, Tolmachev, Vladimir, Karlström, Amelie Eriksson, Altai, Mohamed

“…Pretargeting is a promising strategy to reach high imaging contrast in a shorter time than by targeting with directly radiolabeled monoclonal antibodies…”
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Recombinant Spider Silk as Mediator for One‐Step, Chemical‐Free Surface Biofunctionalization by Horak, Josef, Jansson, Ronnie, Dev, Apurba, Nilebäck, Linnea, Behnam, Kiarash, Linnros, Jan, Hedhammar, My, Karlström, Amelie Eriksson

“…A unique strategy for effective, versatile, and facile surface biofunctionalization employing a recombinant spider silk protein genetically functionalized with…”
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Surface Charge Sensitivity of Silicon Nanowires:  Size Dependence by Elfström, Niklas, Juhasz, Robert, Sychugov, Ilya, Engfeldt, Torun, Karlström, Amelie Eriksson, Linnros, Jan

“…Silicon nanowires of different widths were fabricated in silicon on insulator (SOI) material using conventional process technology combined with electron-beam…”
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Design, Preparation, and Characterization of PNA-Based Hybridization Probes for Affibody-Molecule-Mediated Pretargeting by Westerlund, Kristina, Honarvar, Hadis, Tolmachev, Vladimir, Eriksson Karlström, Amelie

“…In radioimmunotherapy, the contrast between tumor and normal tissue can be improved by using a pretargeting strategy with a primary targeting agent, which is…”
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Evaluation of an antibody-PNA conjugate as a clearing agent for antibody-based PNA-mediated radionuclide pretargeting by Myrhammar, Anders, Vorobyeva, Anzhelika, Westerlund, Kristina, Yoneoka, Shuichiro, Orlova, Anna, Tsukahara, Takehiko, Tolmachev, Vladimir, Karlström, Amelie Eriksson, Altai, Mohamed

“…Radionuclide molecular imaging of cancer-specific targets is a promising method to identify patients for targeted antibody therapy. Radiolabeled full-length…”
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Influence of molecular size and zeta potential in electrokinetic biosensing by Sahu, Siddharth Sourabh, Stiller, Christiane, Cavallaro, Sara, Karlström, Amelie Eriksson, Linnros, Jan, Dev, Apurba

“…Electrokinetic principles such as streaming current and streaming potential are extensively used for surface characterization. Recently, they have also been…”
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Feasibility of Affibody-Based Bioorthogonal Chemistry-Mediated Radionuclide Pretargeting by Altai, Mohamed, Perols, Anna, Tsourma, Maria, Mitran, Bogdan, Honarvar, Hadis, Robillard, Marc, Rossin, Raffaella, ten Hoeve, Wolter, Lubberink, Mark, Orlova, Anna, Karlström, Amelie Eriksson, Tolmachev, Vladimir

“…Affibody molecules constitute a new class of probes for radionuclide tumor targeting. The small size of Affibody molecules is favorable for rapid localization…”
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Electrokinetic sandwich assay and DNA mediated charge amplification for enhanced sensitivity and specificity by Sahu, Siddharth Sourabh, Stiller, Christiane, Gomero, Elizabeth Paz, Nagy, Ábel, Karlström, Amelie Eriksson, Linnros, Jan, Dev, Apurba

“…An electrical immuno-sandwich assay utilizing an electrokinetic-based streaming current method for signal transduction is proposed. The method records the…”
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Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeutics by Nagy, Ábel, Ulmert, David, Zedan, Wahed, Storey, Claire M., Park, Julie, Geres, Susanne, Lückerath, Katharina, Sjöström, Kjell, Westin, Hadis, Peekhaus, Norbert, Thorek, Daniel LJ, Karlström, Amelie Eriksson, Altai, Mohamed

“…Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to…”
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Silicon Nanoribbons for Electrical Detection of Biomolecules by Elfström, Niklas, Karlström, Amelie Eriksson, Linnros, Jan

“…Direct electrical detection of biomolecules at high sensitivity has recently been demonstrated using semiconductor nanowires. Here we demonstrate that…”
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Radiotheranostic Agents in Hematological Malignancies by Caers, Jo, Duray, Elodie, Vrancken, Louise, Marcion, Guillaume, Bocuzzi, Valentina, De Veirman, Kim, Krasniqi, Ahmet, Lejeune, Margaux, Withofs, Nadia, Devoogdt, Nick, Dumoulin, Mireille, Karlström, Amelie Eriksson, D’Huyvetter, Matthias

“…Radioimmunotherapy (RIT) is a cancer treatment that combines radiation therapy with tumor-directed monoclonal antibodies (Abs). Although RIT had been…”
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