Regional lung ventilation in humans during hypergravity studied with quantitative SPECT

Highlights • Hypergravity causes arterial desaturation in humans. • Hypergravity causes anti-gravitational redistribution of lung perfusion. • We study ventilation during hypergravity using Technegas and SPECT. • The results show a redistribution of ventilation in the same direction as perfusion. •...

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Bibliographic Details
Published in:Respiratory physiology & neurobiology Vol. 189; no. 3; pp. 558 - 564
Main Authors: Ax, M, Karlsson, L.L, Sanchez-Crespo, A, Lindahl, S.G.E, Linnarsson, D, Mure, M, Petersson, J
Format: Journal Article
Language:English
Published: Netherlands Elsevier B.V 01-12-2013
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Summary:Highlights • Hypergravity causes arterial desaturation in humans. • Hypergravity causes anti-gravitational redistribution of lung perfusion. • We study ventilation during hypergravity using Technegas and SPECT. • The results show a redistribution of ventilation in the same direction as perfusion. • We suggest that desaturation is caused by quantitatively different redistributions of regional perfusion and ventilation.
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ISSN:1569-9048
1878-1519
1878-1519
DOI:10.1016/j.resp.2013.08.007