Search Results - "Karlo, J C"

Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease by Casali, Brad T, Corona, Angela W, Mariani, Monica M, Karlo, J Colleen, Ghosal, Kaushik, Landreth, Gary E

“…Alzheimer's disease (AD) is a highly prevalent disorder for which there are no effective therapies. Accumulation of amyloid β (Aβ) peptides in the brain is…”
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Disrupted ERK signaling during cortical development leads to abnormal progenitor proliferation, neuronal and network excitability and behavior, modeling human neuro-cardio-facial-cutaneous and related syndromes by Pucilowska, Joanna, Puzerey, Pavel A, Karlo, J Colleen, Galán, Roberto F, Landreth, Gary E

“…Genetic disorders arising from copy number variations in the ERK (extracellular signal-regulated kinase) MAP (mitogen-activated protein) kinases or mutations…”
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Deletion of ERK2 Mitogen-Activated Protein Kinase Identifies Its Key Roles in Cortical Neurogenesis and Cognitive Function by Samuels, Ivy S, Karlo, J. Colleen, Faruzzi, Alicia N, Pickering, Kathryn, Herrup, Karl, Sweatt, J. David, Saitta, Sulagna C, Landreth, Gary E

“…The mitogen-activated protein (MAP) kinases ERK1 and ERK2 are critical intracellular signaling intermediates; however, little is known about their…”
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β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis by Combs, Colin K., Karlo, J. Colleen, Kao, Shih-Chu, Landreth, Gary E.

“…Reactive microglia associated with the β-amyloid plaques in Alzheimer's disease (AD) brains initiate a sequence of inflammatory events integral to the disease…”
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Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor- -Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease by Mandrekar-Colucci, S., Karlo, J. C., Landreth, G. E.

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Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of β-Amyloid-Stimulated Proinflammatory Responses and Neurotoxicity by PPARγ Agonists by Combs, Colin K., Johnson, Derrick E., Karlo, J. Colleen, Cannady, Steven B., Landreth, Gary E.

“…Alzheimer's disease (AD) is characterized by the extracellular deposition of β-amyloid fibrils within the brain and the subsequent association and phenotypic…”
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Regulation of β-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor α by Combs, Colin K, Bates, Patricia, Karlo, J.Colleen, Landreth, Gary E

“…Amyloid deposition within the brains of Alzheimer's Disease patients results in the activation of microglial cells and the induction of a local inflammatory…”
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A novel cDNA from Drosophila encoding a protein with similarity to mammalian cysteine-rich secretory proteins, wasp venom antigen 5, and plant group 1 pathogenesis-related proteins by Schreiber, Michael C, Karlo, J.Colleen, Kovalick, Gae E

“…The CAP protein family is made up of a group of secreted proteins that share sequence similarity. Members of this family are found in animals, plants, and…”
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Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of beta -Amyloid-Stimulated Proinflammatory Responses and Neurotoxicity by PPARgamma Agonists by Combs, Colin K, Johnson, Derrick E, Karlo, J. Colleen, Cannady, Steven B, Landreth, Gary E

“…Alzheimer's disease (AD) is characterized by the extracellular deposition of beta-amyloid fibrils within the brain and the subsequent association and…”
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beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis by Combs, C K, Karlo, J C, Kao, S C, Landreth, G E

“…Reactive microglia associated with the beta-amyloid plaques in Alzheimer's disease (AD) brains initiate a sequence of inflammatory events integral to the…”
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