Search Results - "Karlin, David A"

Randomized Phase II Study of Bevacizumab in Combination With Chemotherapy in Previously Untreated Extensive-Stage Small-Cell Lung Cancer: Results From the SALUTE Trial by SPIGEL, David R, TOWNLEY, Peter M, WATERHOUSE, David M, LIANG FANG, ADIGUZEL, Ibrahim, HUANG, Jane E, KARLIN, David A, FAORO, Leonardo, SCAPPATICCI, Frank A, SOCINSKI, Mark A

“…Because of promising efficacy signals in single-arm studies, a placebo-controlled, double-blind, randomized phase II trial was designed to assess the efficacy…”
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Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors by Wesolowski, Robert, Sharma, Neelesh, Reebel, Laura, Rodal, Mary Beth, Peck, Alexandra, West, Brian L., Marimuthu, Adhirai, Severson, Paul, Karlin, David A., Dowlati, Afshin, Le, Mai H., Coussens, Lisa M., Rugo, Hope S.

“…Purpose: To evaluate the safety, recommended phase II dose (RP2D) and efficacy of pexidartinib, a colony stimulating factor receptor 1 (CSF-1R) inhibitor, in…”
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Phase II Study of Picoplatin As Second-Line Therapy for Patients With Small-Cell Lung Cancer by Eckardt, John R, Bentsion, Dimitri L, Lipatov, Oleg N, Polyakov, Igor S, Mackintosh, Frederick R, Karlin, David A, Baker, Gizelle S, Breitz, Hazel B

“…This study was designed to confirm the efficacy and safety of picoplatin, a cisplatin analog designed to overcome platinum resistance, in patients with…”
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Hypergastrinemia and colorectal carcinogenesis in the rat by Karlin, D A, McBath, M, Jones, R D, Elwyn, K E, Romsdahl, M M

“…Our objective was to determine whether chronic hypergastrinemia enhances chemical induction of rat colorectal cancers. Forty-five rats were randomized to sham…”
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Phase II Study of Picoplatin As Second-Line Therapy for Patients With Small-Cell Lung Cancer by ECKARDT, John R, BENTSION, Dimitri L, LIPATOV, Oleg N, POLYAKOV, Igor S, MACKINTOSH, Frederick R, KARLIN, David A, BAKER, Gizelle S, BREITZ, Hazel B

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Comparison of colon cleansing methods in preparation for colonoscopy by DiPalma, J A, Brady, 3rd, C E, Stewart, D L, Karlin, D A, McKinney, M K, Clement, D J, Coleman, T W, Pierson, W P

“…Colonoscopy cleansing regimens were evaluated in 197 patients randomized in two study phases to one of four methods: group 1 (64 patients), 3-day clear liquid…”
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Prolonged survival and effective palliation in patients with squamous cell carcinoma of the esophagus following endoscopic laser therapy by Karlin, D A, Fisher, R S, Krevsky, B

“…Endoscopic laser therapy provides effective symptomatic palliation for patients with squamous cell carcinoma of the esophagus. To investigate whether this…”
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Trophic effects of gastrin on colorectal neoplasms in the rat by McGregor, D B, Jones, R D, Karlin, D A, Romsdahl, M M

“…This study was designed to determine the effect of gastrin on colorectal neoplasms in the rat. Multiple colon and rectal cancers were induced in each of 57…”
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5-fluorouracil, Adriamycin, and mitomycin-C (FAM) chemotherapy for advanced adenocarcinoma of the pancreas by Smith, F P, Hoth, D F, Levin, B, Karlin, D A, MacDonald, J S, Woolley, 3rd, P V, Schein, P S

“…Thirty-nine patients with advanced metastatic adenocarcinoma of the pancreas were treated with a combination of 5-fluorouracil, Adriamycin, and mitomycin-C…”
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Breath methane excretion in patients with unresected colorectal cancer by Karlin, D A, Jones, R D, Stroehlein, J R, Mastromarino, A J, Potter, G D

“…The objective of our study was to verify or refute the observation that patients with unresected colorectal cancer are more likely to be breath methane…”
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Cis-diaminodichloroplatinum (II) chemotherapy for advanced adenocarcinoma of the upper gastrointestinal tract by Kantarjian, H, Ajani, J A, Karlin, D A

“…A phase II study of cis-diaminodichloroplatinum (II) (cis-DDP) was carried out in 55 patients with advanced adenocarcinoma of the upper gastrointestinal tract…”
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Military medicine

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Meningeal metastasis from rectal carcinoma with elevated cerebrospinal fluid carcinoembryonic antigen by Bresalier, R S, Karlin, D A

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Comparison of effects of pentagastrin and gastrin on rat colon mucosa by McGregor, D B, Jones, R D, Karlin, D A, Romsdahl, M M

“…The trophic effect of chronic endogenous hypergastrinemia is compared with that of short term injected pentagastrin on colon mucosa of rats. Hypergastrinemia…”
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Effect of dioctyl sodium sulfosuccinate feeding on rat colorectal 1,2-dimethylhydrazine carcinogenesis by Karlin, D A, O'Donnell, R T, Jensen, W E

“…The 1,2-dimethylhydrazine (DMH) rodent model for colorectal carcinogenesis was used to explore the effect of dietary dioctyl sodium sulfosuccinate (DSS) on…”
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Phase II clinical evaluation of AZQ in colorectal cancer by Bedikian, A Y, Stroehlein, J R, Karlin, D A, Korinek, J, Bodey, G P

“…Thirty patients with measurable metastatic colorectal cancer refractory to 5-fluorouracil-containing regimens, received AZQ (1,4-cyclohexadiene-1,4-dicarbamic…”
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Sequential phase II studies of chemotherapy for colorectal cancer with 5-fluorouracil and vindesine with or without methyl-1,3 cis(2 chloroethyl)-1-nitrosourea by Stroehlein, J R, Bedikian, A Y, Karlin, D A, Valdivieso, M, Bennetts, R W, Bodey, G P

“…Vindesine, a newer vinca alkaloid, has been demonstrated to have activity against colorectal cancer during phase I studies. This report describes the results…”
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Phase II evaluation of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (PCNU, NSC 95466) in patients with metastatic colorectal cancer by Bedikian, A Y, Stroehlein, J R, Karlin, D A, Bennetts, R W, Stewart, D J, Bodey, G P

“…Thirty-two patients with measurable metastatic colorectal cancer refractory to 5-fluorouracil-containing regimens received PCNU…”
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