Search Results - "Karle, N."

Hereditary spastic paraplegia: Clinicogenetic lessons from 608 patients by Schüle, Rebecca, Wiethoff, Sarah, Martus, Peter, Karle, Kathrin N., Otto, Susanne, Klebe, Stephan, Klimpe, Sven, Gallenmüller, Constanze, Kurzwelly, Delia, Henkel, Dorothea, Rimmele, Florian, Stolze, Henning, Kohl, Zacharias, Kassubek, Jan, Klockgether, Thomas, Vielhaber, Stefan, Kamm, Christoph, Klopstock, Thomas, Bauer, Peter, Züchner, Stephan, Liepelt-Scarfone, Inga, Schöls, Ludger

“…Objective Hereditary spastic paraplegias (HSPs) are genetically driven disorders with the hallmark of progressive spastic gait disturbance. To investigate the…”
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Systematic analysis of virga and its impact on surface particulate matter observations by Karle, Nakul N, Sakai, Ricardo K, Fitzgerald, Rosa M, Ichoku, Charles, Mercado, Fernando, Stockwell, William R

“…Studies focusing on virga are rare, even though it is a commonly occurring phenomenon. In this study, we investigated aerosol backscatter profiles from a…”
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3D MAPPING OF BURIED PIPES IN MULTI-CHANNEL GPR DATA by Karle, N., Boldt, M., Thiele, A., Thoennessen, U.

“…Ground Penetrating Radar (GPR) allows a non-destructive analysis of the subsurface by using electromagnetic waves. GPR is used in application fields such as…”
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Electronic and Structural Properties of C60 and Sc3N@C80 Supported on Graphene Nanoflakes by Reveles, J. Ulises, Karle, Nakul N, Baruah, Tunna, Zope, Rajendra R

“…A theoretical study on the geometric and electronic structure of C60 and Sc3N@C80 absorbed on pristine graphene nanoflakes (GNFs) is presented. C60 is found to…”
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Reinterpreting Trends: The Impact of Methodological Changes on Reported Sea Salt Aerosol Levels by Karle, Nakul N., Sakai, Ricardo K., Chiao, Sen, Fitzgerald, Rosa M., Stockwell, William R.

“…Since 2017, there has been a considerable increase in the recorded sea salt aerosol (SSA) levels across the United States, particularly the economically…”
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Autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS): expanding the genetic, clinical and imaging spectrum by Synofzik, Matthis, Soehn, Anne S, Gburek-Augustat, Janina, Schicks, Julia, Karle, Kathrin N, Schüle, Rebecca, Haack, Tobias B, Schöning, Martin, Biskup, Saskia, Rudnik-Schöneborn, Sabine, Senderek, Jan, Hoffmann, Karl-Titus, MacLeod, Patrick, Schwarz, Johannes, Bender, Benjamin, Krüger, Stefan, Kreuz, Friedmar, Bauer, Peter, Schöls, Ludger

“…Mutations in SACS, leading to autosomal-recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), have been identified as a frequent cause of recessive…”
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Spastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP model by Füger, Petra, Sreekumar, Vrinda, Schüle, Rebecca, Kern, Jeannine V, Stanchev, Doychin T, Schneider, Carola D, Karle, Kathrin N, Daub, Katharina J, Siegert, Vera K, Flötenmeyer, Matthias, Schwarz, Heinz, Schöls, Ludger, Rasse, Tobias M

“…Hereditary spastic paraplegias (HSPs) comprise a group of genetically heterogeneous neurodegenerative disorders characterized by spastic weakness of the lower…”
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Pure and syndromic optic atrophy explained by deep intronic OPA1 mutations and an intralocus modifier by BONIFERT, Tobias, KARLE, Kathrin N, WOLF, Julia, GONZALEZ, Michael A, SPEZIANI, Fiorella, SCHÜLE, Rebecca, ZÜCHNER, Stephan, SCHÖLS, Ludger, WISSINGER, Bernd, SYNOFZIK, Matthis, TONAGEL, Felix, BATRA, Marion, WILHELM, Christian, THEURER, Yvonne, SCHOENFELD, Caroline, KLUBA, Torsten, KAMENISCH, York, CARELLI, Valerio

“…The genetic diagnosis in inherited optic neuropathies often remains challenging, and the emergence of complex neurological phenotypes that involve optic…”
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Environmental Assessment and Monitoring of Heavy Metals in New York City Potable Water Systems: Case Study at Medgar Evers College, Correlation Analysis, and Public Health Impacts by Blaszczak-Boxe, Christopher S, Karle, Nakul N, Wang, Shujie, Yu, Manzhu, Golosov, Nikolay, Riyad, Mohammed, Smith, Kayla, Hollet, Ty, Abdul-Hamid, Bishara, St. Hillaire, Dickens, Sen, Paramita

“…Reinforced by this study, New York City has one of the cleanest water systems in the world. Medgar Evers College (MEC) serves 7000 students/1050 faculty/staff…”
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Particulate Matter in the American Southwest: Detection and Analysis of Dust Storms Using Surface Measurements and Ground-Based LIDAR by Guzman-Gonzalez, Joscelyne, Fitzgerald, Rosa M., Karle, Nakul N., Sakai, Ricardo K., Stockwell, William R.

“…This research study focuses on the coupling between particulate matter and the planetary boundary layer. Particulate matter affects human health and it is a…”
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Socioeconomic and sociodemographic correlations to COVID-19 variability in the United States in 2020 by Golosov, Nikolay, Wang, Shujie, Yu, Manzhu, Karle, Nakul N, Ideki, Oye, Abdul-Hamid, Bishara, Blaszczak-Boxe, Christopher

“…The COVID-19 pandemic provided an additional spotlight on the longstanding socioeconomic/health impacts of redlining and has added to the myriad of…”
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Winter and Wildfire Season Optical Characterization of Black and Brown Carbon in the El Paso-Ciudad Juárez Airshed by Lara, Pamela, Fitzgerald, Rosa M., Karle, Nakul N., Talamantes, Jose, Miranda, Miranda, Baumgardner, Darrel, Stockwell, William R.

“…Black (EBC) and Brown (BrC) Carbon are ubiquitous constituents of atmospheric particulate matter that affect people’s health, disrupt ecosystems, and modulate…”
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Multi-Scale Atmospheric Emissions, Circulation and Meteorological Drivers of Ozone Episodes in El Paso-Juárez Airshed by Karle, Nakul N., Fitzgerald, Rosa M., Sakai, Ricardo K., Sullivan, David W., Stockwell, William R.

“…Ozone pollution has been prevalent in the El Paso-Juárez Airshed (EPJA), especially in the past few decades, and it has been on the rise recently. The spatial…”
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DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients undergoing alcohol treatment by Brückmann, Christof, Islam, Sumaiya A., MacIsaac, Julia L., Morin, Alexander M., Karle, Kathrin N., Di Santo, Adriana, Wüst, Richard, Lang, Immanuel, Batra, Anil, Kobor, Michael S., Nieratschker, Vanessa

“…Several studies have shown an association of alcohol dependence with DNA methylation (DNAm), suggesting that environmentally-induced changes on epigenomic…”
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Amplicon-based high-throughput pooled sequencing identifies mutations in CYP7B1 and SPG7 in sporadic spastic paraplegia patients by Schlipf, NA, Schüle, R, Klimpe, S, Karle, KN, Synofzik, M, Schicks, J, Riess, O, Schöls, L, Bauer, P

“…Schlipf NA, Schüle R, Klimpe S, Karle KN, Synofzik M, Schicks J, Riess O, Schöls L, Bauer P. Amplicon‐based high‐throughput pooled sequencing identifies…”
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In Silico Docking and Admet Prediction of a Novel Antibacterial Derivatives (Schiff Base) Targeting Dihydropteroate Synthase (1aj2) by Shubham N Karle, Megha T Salve

“…Schiff base-containing (imine or azomethine–C=N–) derivatives have been investigated in relation to a broad range of activity, including antibacterial…”
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Investigation of the Successive Ozone Episodes in the El Paso–Juarez Region in the Summer of 2017 by Karle, Nakul N., Mahmud, Suhail, Sakai, Ricardo K., Fitzgerald, Rosa M., Morris, Vernon R., Stockwell, William R.

“…The adjacent cities of El Paso in Texas, USA, and Juarez in Mexico commonly experience pollution episodes, especially during the summer months. In the summer…”
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Axonal transport deficit in a KIF5A–/– mouse model by Karle, Kathrin N., Möckel, Diana, Reid, Evan, Schöls, Ludger

“…Hereditary spastic paraplegia (HSP) is a neurodegenerative disorder preferentially affecting the longest corticospinal axons. More than 40 HSP genetic loci…”
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Imaging features in conventional MRI, spectroscopy and diffusion weighted images of hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) by Bender, Benjamin, Klose, Uwe, Lindig, Tobias, Biskup, Saskia, Nägele, Thomas, Schöls, Ludger, Karle, Kathrin N.

“…Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) is a rare autosomal dominant disease caused by mutations within the colony stimulating…”
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A spastic paraplegia mouse model reveals REEP1-dependent ER shaping by Beetz, Christian, Koch, Nicole, Khundadze, Mukhran, Zimmer, Geraldine, Nietzsche, Sandor, Hertel, Nicole, Huebner, Antje-Kathrin, Mumtaz, Rizwan, Schweizer, Michaela, Dirren, Elisabeth, Karle, Kathrin N, Irintchev, Andrey, Alvarez, Victoria, Redies, Christoph, Westermann, Martin, Kurth, Ingo, Deufel, Thomas, Kessels, Michael M, Qualmann, Britta, Hübner, Christian A

“…Axonopathies are a group of clinically diverse disorders characterized by the progressive degeneration of the axons of specific neurons. In hereditary spastic…”
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