Search Results - "Karlawish, Jason H.T."

Identifying ambulatory cancer patients at risk of impaired capacity to consent to research by Casarett, David J, Karlawish, Jason H.T, Hirschman, Karen B

“…Ethicists and others have expressed concerns that some patients with cancer might lack adequate decision-making capacity to give consent for research. Although…”
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Current state of research on decision-making competence of cognitively impaired elderly persons by Kim, Scott Y H, Karlawish, Jason H T, Caine, Eric D

“…As the number of cognitively impaired elderly persons increases, the need for evidence-based assessments of their capacity to consent to medical treatment and…”
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Research Involving Cognitively Impaired Adults by Karlawish, Jason H.T

“…Although the federal government funds research to improve the lives of critically ill adults and of the people who care for them, recent investigations show…”
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Do Alzheimer's Disease Patients Want to Participate in a Treatment Decision, and Would Their Caregivers Let Them? by Hirschman, Karen B., Joyce, Colette M., James, Bryan D., Xie, Sharon X., Karlawish, Jason H. T.

“…Purpose: This study was designed to examine the factors associated with the preferences of Alzheimer's disease patients to participate in a decision to use an…”
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Are Special Ethical Guidelines Needed For Palliative Care Research? by Casarett, David J, Karlawish, Jason H.T

“…Recent studies have made it clear that there are substantial opportunities to improve end-of-life care. Doing so will require solid evidence on which to base…”
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Hypertensive patients' willingness to participate in placebo-controlled trials: implications for recruitment efficiency by Halpern, Scott D, Karlawish, Jason H.T, Casarett, David, Berlin, Jesse A, Townsend, Raymond R, Asch, David A

“…Underenrollment and selective enrollment plague many clinical trials. Little is known about why hypertensive patients agree or refuse to participate in…”
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A consensus-based approach to providing palliative care to patients who lack decision-making capacity by KARLAWISH, J. H. T, QUILL, T, MEIER, D. E

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Conducting Research That Involves Subjects at the End of Life Who Are Unable to Give Consent by Karlawish, Jason H.T

“…This paper examines the conditions that describe when it is appropriate to conduct research that enrolls a subject near the end-of-life who cannot provide an…”
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Cognitive performance characteristics of individuals with normal or pathological CSF and MRI biomarkers of Alzheimer's disease by Moelter, Stephen T, Davatzikos, Christos, Moberg, Paul J, Koka, Deepthi, Shaw, Leslie M, Trojanowski, John Q, Arnold, Steven E, Karlawish, Jason H.T, Clark, Christopher M

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P3-007: Instability of a diagnosis of mild cognitive impairment based on a brief screening assessment of English- and Spanish-speaking individuals in a general care clinic by Cartmell, Su P, Xie, Sharon X, Martinez, Patricia, Nunez, Jessica, Janis, Peter, Baek, Young, Karlawish, Jason H.T, Arnold, Steven E, Clark, Christopher M

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Addressing the challenges of transforming laboratory advances into Alzheimer's Disease treatments by KARLAWISH, Jason H. T, CLARK, Christopher M

“…This essay addresses the challenges of clinical trials to develop treatments for Alzheimer's Disease (AD). The issues covered are enrolling subjects, defining…”
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Protection of Research Subjects by Kaufman, Jeffrey L, Bateman, Brian T, Meyers, Philip M, Schumacher, H. Christian, Berger, Jeffrey T, Karlawish, Jason H.T, Campbell, Duncan J, Karnad, Anand, Sudbo, Jon, Miller, Franklin G, Rosenstein, Donald L, Tremaine, William J, Noble, John H, Sharav, Vera H, Pesando, John M, Drazen, Jeffrey M

“…To the Editor: Regarding the study by the Acute Respiratory Distress Syndrome (ARDS) Network, discussed by Steinbrook (April 3 issue), 1 some may wonder…”
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The Continuing Unethical Conduct of Underpowered Clinical Trials by Halpern, Scott D, Karlawish, Jason H. T, Berlin, Jesse A

“…Despite long-standing critiques of the conduct of underpowered clinical trials, the practice not only remains widespread, but also has garnered increasing…”
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Identifying the Factors That Facilitate or Hinder Advance Planning by Persons With Dementia by HIRSCHMAN, Karen B, KAPO, Jennifer M, KARLAWISH, Jason H. T

“…We performed semistructured interviews with 30 family members of patients with advanced dementia to identify the factors that facilitate or hinder advance…”
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Alzheimer disease: Current concepts and emerging diagnostic and therapeutic strategies by CLARK, Christopher M, KARLAWISH, Jason H. T

“…Alzheimer disease is a complex neurodegenerative dementing illness. It has become a major public health problem because of its increasing prevalence, long…”
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Determining When Quality Improvement Initiatives Should Be Considered Research: Proposed Criteria and Potential Implications by Casarett, David, Karlawish, Jason H. T, Sugarman, Jeremy

“…Quality improvement initiatives have become a major force in shaping health care. These initiatives are diverse but share a common goal of generating knowledge…”
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Why doesn't a family member of a person with advanced dementia use a substituted judgment when making a decision for that person? by Hirschman, Karen B, Kapo, Jennifer M, Karlawish, Jason H T

“…The objective of this study was to identify what standard of decision making a family member uses when making medical decisions for their relative with…”
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Alzheimer's Disease Patients' and Caregivers' Capacity, Competency, and Reasons to Enroll in an Early-Phase Alzheimer's Disease Clinical Trial by Karlawish, Jason H. T., Casarett, David J., James, Bryan D.

“…OBJECTIVES: To examine the capacity, competency, and reasons for enrolling of patients with Alzheimer's disease (AD) and of their caregivers in an early phase…”
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How do patients with Alzheimer disease rate their overall quality of life? by James, Bryan D, Xie, Sharon X, Karlawish, Jason H T

“…The authors asked how Alzheimer disease (AD) patients assess their overall quality of life (QOL) and sought to determine the characteristics associated with…”
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Rate of Decline in Alzheimer Disease Measured by a Dementia Severity Rating Scale by XIE, Sharon X, EWBANK, Douglas C, CHITTAMS, Jesse, KARLAWISH, Jason H. T, ARNOLD, Steven E, CLARK, Christopher M

“…To measure clinically relevant change in Alzheimer disease (AD) using a family member-completed Dementia Severity Rating Scale (DSRS) questionnaire. Measuring…”
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