Search Results - "Karkoska, Kristine"

Molecular and environmental contributors to neurological complications in sickle cell disease by Karkoska, Kristine A, Gollamudi, Jahnavi, Hyacinth, Hyacinth I

“…Sickle cell disease (SCD) is an inherited hemoglobinopathy in which affected hemoglobin polymerizes under hypoxic conditions resulting in red cell distortion…”
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Inherited disorders of hemoglobin: A review of old and new diagnostic methods by Franco, Emily, Karkoska, Kristine A, McGann, Patrick T

“…The genetic regulation of hemoglobin is complex and there are a number of genetic abnormalities that result in clinically important hemoglobin disorders. Here,…”
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Academic Challenges and School Service Utilization in Children with Sickle Cell Disease by Karkoska, Kristine A., Haber, Kenneth, Elam, Megan, Strong, Sarah, McGann, Patrick T.

“…To describe the academic concerns and risk strata of children with sickle cell disease (SCD) as identified through a parent-directed screening tool and to…”
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Quantifying dilated perivascular spaces in children with sickle cell disease by Karkoska, Kristine A, Gollamudi, Jahnavi, Sawyer, Russell P, Woo, Daniel, Hyacinth, Hyacinth I

“…Sickle cell disease (SCD)-related neurological effects are particularly devastating. Dilated perivascular spaces (dPVS) are a well-described component of…”
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Uncovering an undisclosed diagnosis: a glucose‐6‐phosphate dehydrogenase deficiency diagnosis in a critically ill adult by Kasturiarachi, Brittany M., Robinson, David, Karkoska, Kristine, Gollamudi, Jahnavi

“…Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency affects over 400 million people worldwide. The most common variant of G6PD deficiency in the United States…”
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A bone to pick-cellular and molecular mechanisms of bone pain in sickle cell disease by Gollamudi, Jahnavi, Karkoska, Kristine A, Gbotosho, Oluwabukola T, Zou, Wei, Hyacinth, Hyacinth I, Teitelbaum, Steven L

“…The bone is one of the most commonly affected organs in sickle cell disease (SCD). Repeated ischemia, oxidative stress and inflammation within the bone is…”
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Effect of Blood Transfusion on Cerebral Hemodynamics and Vascular Topology Described by Computational Fluid Dynamics in Sickle Cell Disease Patients by Sawyer, Russell P, Pun, Sirjana, Karkoska, Kristine A, Clendinen, Cherita A, DeBaun, Michael R, Gutmark, Ephraim, Barrile, Riccardo, Hyacinth, Hyacinth I

“…The main objective of this study was to demonstrate that computational fluid dynamics (CFD) modeling can be used to study the contribution of covert and overt…”
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Neuroprotection: further evidence for the early and universal use of hydroxyurea in children with sickle cell disease by Karkoska, Kristine

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Characterization of a genomic divergence island between black-and-yellow and gopher Sebastes rockfishes by BUONACCORSI, VINCENT P., NARUM, SHAWN R., KARKOSKA, KRISTINE A., GREGORY, STEVEN, DEPTOLA, TRAVIS, WEIMER, ALEXANDER B.

“…Islands of high genomic divergence that contain genes of evolutionary significance may form between diverging species. The gopher rockfish, Sebastes carnatus,…”
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Changing Trends in Sickle Cell Disease-Related Mortality in the United States over Four Decades by Karkoska, Kristine, McGann, Patrick T.

“…Introduction: Sickle cell disease (SCD) causes significant morbidity and early mortality. The Cooperative Study of Sickle Cell Disease estimated median life…”
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Trends in Sickle Cell Disease Mortality: 1979–2020 by Karkoska, Kristine A., McGann, Patrick T.

“…BACKGROUND AND OBJECTIVES: Although sickle cell disease (SCD)-related childhood mortality in the United States significantly improved in the 1990s, unclear is…”
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Abstract 718: Cerebral Small Vessel Disease In Children With Sickle Cell Disease by Hyacinth, Hyacinth I, Karkoska, Kristine A, Sawyer, Russell P

“…Abstract only Introduction: The neurological complications of sickle cell disease (SCD) are particularly devastating and range from “overt stroke” to cerebral…”
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Quantifying Dilated Perivascular Spaces in Children with Sickle Cell Disease by Karkoska, Kristine Anne, Sawyer, Russell, Hyacinth, Hyacinth I

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Early Hydroxyurea Use May be Neuroprotective in Children with Sickle Cell Anemia by Karkoska, Kristine Anne, Pfeiffer, Amanda, McGann, Patrick T.

“…Introduction: The neurologic changes of sickle cell anemia (SCA) are particularly devastating and include acute stroke, silent infarctions, and cerebral…”
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How I approach disease‐modifying therapy in children with sickle cell disease in an era of novel therapies by Karkoska, Kristine, McGann, Patrick T.

“…Finally,after decades of stagnation, the therapeutic landscape for sickle cell disease (SCD) is changing with an increasing number of novel therapeutics…”
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Academic Challenges and Concerns for Children with Sickle Cell Disease: Analysis of a Hospital-Based School Intervention Program by Karkoska, Kristine Anne, Haber, Kenneth, McGann, Patrick T.

“…Introduction: Neurocognitive deficits are a well-known complication in patients with sickle cell disease (SCD) and are often associated with overt stroke and…”
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Severe infusion‐related reaction to crizanlizumab in an adolescent with sickle cell disease by Karkoska, Kristine, Quinn, Charles T., Clapp, Kelly, McGann, Patrick T.

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Improving Transition of Emerging Adults with Sickle Cell Disease to Adult Care through a Multidisciplinary Process: The Development of a Transition Clinic to Support Transition Success by Fenchel, Lynette, Jackson, Felisha, Walker, Brittany, Manuel, Chandra, Hooks, Dajia, Allen, Tyesha, Thant, Mamie Myo, Karkoska, Kristine, Smart, Luke R., Joffe, Naomi E, Niss, Omar

“…The transition period from pediatric to adult care is challenging for people with sickle cell disease (SCD). Emerging adults with SCD who do not successfully…”
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Early hydroxyurea use is neuroprotective in children with sickle cell anemia by Karkoska, Kristine, Pfeiffer, Amanda, Beebe, Dean W., Quinn, Charles T., Niss, Omar, McGann, Patrick T.

“…Children with sickle cell disease (SCD) who began hydroyxurea before age five years scored no differently on a measure of cognitive funciton than age, sex, and…”
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Academic Challenges and School Service Utilization in Children With Sickle Cell Disease by Karkoska, Kristine

“…Objectives: To describe the academic concerns and risk strata of a pediatric sickle cell population as identified through a parent-directed screening tool and…”
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