Search Results - "Karki, Megha"
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Phosphorylation, oligomerization and self-assembly in water under potential prebiotic conditions
Published in Nature chemistry (01-02-2018)“…Prebiotic phosphorylation of (pre)biological substrates under aqueous conditions is a critical step in the origins of life. Previous investigations have had…”
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Nitrogenous Derivatives of Phosphorus and the Origins of Life: Plausible Prebiotic Phosphorylating Agents in Water
Published in Life (Basel, Switzerland) (29-07-2017)“…Phosphorylation under plausible prebiotic conditions continues to be one of the defining issues for the role of phosphorus in the origins of life processes. In…”
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Bromination of Olefins with HBr and DMSO
Published in Journal of organic chemistry (03-04-2015)“…A simple and inexpensive methodology is reported for the conversion of alkenes to 1,2-dibromo alkanes via oxidative bromination using HBr paired with dimethyl…”
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Cyclophospholipids Enable a Protocellular Life Cycle
Published in ACS nano (12-12-2023)“…There is currently no plausible path for the emergence of a self-replicating protocell, because prevalent formulations of model protocells are built with fatty…”
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Cyclophospholipids Increase Protocellular Stability to Metal Ions
Published in Small (Weinheim an der Bergstrasse, Germany) (01-07-2020)“…Model protocells have long been constructed with fatty acids, because these lipids are prebiotically plausible and can, at least theoretically, support a…”
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A sensitive quantitative analysis of abiotically synthesized short homopeptides using ultraperformance liquid chromatography and time-of-flight mass spectrometry
Published in Journal of Chromatography A (25-10-2020)“…•Developed new analytical tool for the analysis of short homopeptides.•Analytical figures of merit experiments were performed to validate the method.•Achieved…”
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Development of Oxidation Reactions Based on Vanadium Pentoxide, Dimethylsulfoxide, and Synthetic Iron-Rich Clays
Published 01-01-2015“…In this dissertation we offer a discussion on the development of three novel oxidation methods. Chapter 1 presents the dehydroaromatization of N-heterocycles…”
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Dissertation -
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Data set for "Cyclophospholipids enable a protocellular life cycle"
Published 19-11-2023“…Publication in ACS Nano can be found here. Toparlaka ÖD, Sebastianelli L, Egas Ortunoc V, Karkic M, Szostak JW, Krishnamurthy R, Mansy SS (2023)…”
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Data Set